The Genetic Lottery

Last updated
The Genetic Lottery: Why DNA Matters for Social Equality
The Genetic Lottery.jpg
First edition
Author Kathryn Paige Harden
GenreNonfiction
Publisher Princeton University Press
Publication date
September 21, 2021 (2021-09-21)
Pages312
ISBN 9780691190808

The Genetic Lottery: Why DNA Matters for Social Equality is a book by psychologist and behavior geneticist Kathryn Paige Harden, a professor of psychology at the University of Texas at Austin. Published on September 21, 2021, by Princeton University Press, the book argues that human genetic variation needs to be acknowledged in order to create a fair and equal society. She encourages people to conceptualize genetic predispositions to greater socioeconomic status and educational attainment as "genetic luck" rather than "superiority" or individual worth. The book also aims to counter pseudoscientific ideas such as race science and eugenics that have been used to explain and justify social inequalities. [1] [2]

Contents

Reviewers said the book describes behavior genetics accurately and accessibly, but many reviewers rejected her message that accommodating genetic inequality would be a valuable to way advance egalitarianism.

Background

Harden was motivated to write The Genetic Lottery to try to change people's minds about what she considers the need for social scientists to consider genetics in their research, and to assuage fears about the negative societal consequences of doing so. [3] She told Gideon Lewis-Kraus that the book was "fundamentally defensive in a lot of ways" in cautioning against over-interpretation of genetic data, such as the results of genome-wide association studies. [4]

Reviews

Jonathan Flint reviewed The Genetic Lottery favorably, concluding, "Harden’s book provides its readers with an accessible introduction to the current state of behavioral genetics...Her well-argued text is an excellent example of how to make difficult genetic concepts clear". [5]

University of Cambridge geneticist Aylwyn Scally also reviewed the book favorably, writing in Nature Ecology & Evolution that it "provides a better basis for debate about these issues and the role of genetics in society than previous contributions in the same sphere, and a corrective to the more notorious of them, which in itself makes it valuable and welcome." [6]

Economist Jason Fletcher published a mixed review of The Genetic Lottery in the journal Population and Development Review . He stated that "The book's main messages will appeal to a variety of researchers, many of whom are uninitiated into behavioral genetics." However, he also criticized the book for what he refers to "an aggressive, persistent bait and switch" because, in the book, Harden almost never discusses sibling studies despite extensively describing genetic differences between biological siblings as a "lottery". [7]

In another mixed review, Portland State University philosopher Bryan Cwik stated, "The book is a masterly tour of the state of the art of behavioral genetics and its relevance for pressing social questions, but despite the ambition and daring nature of its central claim, its effort to make the case for an “anti-eugenic” science and policy is ultimately disappointing." [8]

A negative review of the book in Los Angeles Review of Books written by four academics stated: "While we admire Harden’s social justice aims, we remain unconvinced by her biological explanation for socioeconomic inequality. In making her case to liberals, we believe Harden extrapolates beyond what current scientific results allow. She has expanded an interesting but narrow finding — that DNA influences educational attainment and other social outcomes for individuals of European ancestry in high-income countries — into a unified theory of society and a basis for sweeping social reform." [9]

Another negative review written by Nathaniel Comfort for American Scientist stated, "For a book on applied human genetics published in 2021, The Genetic Lottery is astonishingly blinkered when it comes to race and disability. These things should be de rigueur for a book on progressive social policy." "Understanding natural differences in ability as luck, Harden argues, allows us to reject the idea that ability equals social or moral worth. We avoid eugenics by thinking of difference not as “innate superiority,” but rather as simply a better roll of the genetic dice. However, the two are not mutually exclusive. Harden’s “genetic luck” and good old-fashioned breeding are coextensive.", "All of Harden’s insights or recommendations can be reached without recourse to genetics.", "Harden offers no concrete suggestions for how taking genetics into account would benefit the disadvantaged—and not a word on how to keep it from harming them.", "Harden doesn’t address the hard stuff, such as general literacy, school funding, remedial education, charter schools, and curricular reform." that "Ultimately, the book is more a defense of behavior genetics than an introduction to a truly useful tool for education policy." He concluded: "Hereditarianism [the belief that nature is more important than nurture] has increased inequality in every era of genetics. Harden offers no reason to believe that the genome age will be any different." [2]

Joseph L. Graves reviewed the book in the Lancet , concluding that "Despite Harden’s talent and best intentions, in my view this book does not make a convincing case for how to advance progressive social movements" and arguing that changing the social environment of individuals will be more beneficial to creating social equality than any of the genetically based policy proposals Harden outlines in the book. [10]

In a review published in Evolution , the review authors Graham Coop and Molly Przeworski stated that the book "...leaves us unconvinced, and with the impression of genomics serving as a distraction from much more exigent political conversations." [11] This sparked a response from Kathryn Paige Harden [12] and a counter-response from the authors, arguing that the book "misinterprets findings from genome-wide association studies (GWAS) of educational attainment and overstates their relevance for our understanding of social inequalities". [13]

The April 21, 2022 issue of the New York Review of Books published a negative review of The Genetic Lottery entitled "Why Biology Is Not Destiny". Written by Marcus Feldman and Jessica Riskin, the review claimed that Harden "disguises her radically subjective view of biological essentialism as an objective fact" and compared her writing to the parable of the "boiling frog" in the way that Harden gradually proceeds from less controversial premises to more controversial conclusions. [14] In a 2021 review essay focused on the book, Daphne Martschenko argued that, contrary to the book's contentions, "embracing a political agenda in which genetics matter for social equality will not in practice advance efforts to reduce social inequality." [15]

Related Research Articles

<span class="mw-page-title-main">Heredity</span> Passing of traits to offspring from the species parents or ancestor

Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents. Through heredity, variations between individuals can accumulate and cause species to evolve by natural selection. The study of heredity in biology is genetics.

John Philippe Rushton was a Canadian psychologist and author. He taught at the University of Western Ontario until the early 1990s, and became known to the general public during the 1980s and 1990s for research on race and intelligence, race and crime, and other purported racial correlations.

Race is a categorization of humans based on shared physical or social qualities into groups generally viewed as distinct within a given society. The term came into common usage during the 16th century, when it was used to refer to groups of various kinds, including those characterized by close kinship relations. By the 17th century, the term began to refer to physical (phenotypical) traits, and then later to national affiliations. Modern science regards race as a social construct, an identity which is assigned based on rules made by society. While partly based on physical similarities within groups, race does not have an inherent physical or biological meaning. The concept of race is foundational to racism, the belief that humans can be divided based on the superiority of one race over another.

<i>The Bell Curve</i> 1994 book by Richard J. Herrnstein and Charles Murray

The Bell Curve: Intelligence and Class Structure in American Life is a 1994 book by psychologist Richard J. Herrnstein and political scientist Charles Murray, in which the authors argue that human intelligence is substantially influenced by both inherited and environmental factors and that it is a better predictor of many personal outcomes, including financial income, job performance, birth out of wedlock, and involvement in crime than are an individual's parental socioeconomic status. They also argue that those with high intelligence, the "cognitive elite", are becoming separated from those of average and below-average intelligence, and that this separation is a source of social division within the United States.

<span class="mw-page-title-main">Group selection</span> Proposed mechanism of evolution

Group selection is a proposed mechanism of evolution in which natural selection acts at the level of the group, instead of at the level of the individual or gene.

<i>The Blank Slate</i> 2002 book by Steven Pinker

The Blank Slate: The Modern Denial of Human Nature is a best-selling 2002 book by the cognitive psychologist Steven Pinker, in which the author makes a case against tabula rasa models in the social sciences, arguing that human behavior is substantially shaped by evolutionary psychological adaptations. The book was nominated for the 2003 Aventis Prizes and was a finalist for the Pulitzer Prize.

Researchers have investigated the relationship between race and genetics as part of efforts to understand how biology may or may not contribute to human racial categorization. Today, the consensus among scientists is that race is a social construct, and that using it as a proxy for genetic differences among populations is misleading.

The gene-centered view of evolution, gene's eye view, gene selection theory, or selfish gene theory holds that adaptive evolution occurs through the differential survival of competing genes, increasing the allele frequency of those alleles whose phenotypic trait effects successfully promote their own propagation. The proponents of this viewpoint argue that, since heritable information is passed from generation to generation almost exclusively by DNA, natural selection and evolution are best considered from the perspective of genes.

Hereditarianism is the doctrine or school of thought that heredity plays a significant role in determining human nature and character traits, such as intelligence and personality. Hereditarians believe in the power of genetics to explain human character traits and solve human social and political problems. Hereditarians adopt the view that an understanding of human evolution can extend the understanding of human nature.

Eva Jablonka is an Israeli evolutionary theorist and geneticist, known especially for her interest in epigenetic inheritance. Born in 1952 in Poland, she emigrated to Israel in 1957. She is a professor at the Cohn Institute for the History of Philosophy of Science and Ideas at Tel Aviv University. In 1981 she was awarded the Landau prize of Israel for outstanding Master of Science (M.Sc.) work and in 1988, the Marcus prize for outstanding Ph.D. work. She is a proponent of academic freedom, recognising that on such matters, "academic and political issues cannot really be kept apart", although she is not a proponent of simplistic solutions, and shows a preference to describe her own position.

Research on the heritability of IQ inquires into the degree of variation in IQ within a population that is due to genetic variation between individuals in that population. There has been significant controversy in the academic community about the heritability of IQ since research on the issue began in the late nineteenth century. Intelligence in the normal range is a polygenic trait, meaning that it is influenced by more than one gene, and in the case of intelligence at least 500 genes. Further, explaining the similarity in IQ of closely related persons requires careful study because environmental factors may be correlated with genetic factors.

Marion Julia Lamb was Senior Lecturer at Birkbeck, University of London, before her retirement. She studied the effect of environmental conditions such as heat, radiation and pollution on metabolic activity and genetic mutability in the fruit fly Drosophila. From the late 1980s, Lamb collaborated with Eva Jablonka, researching and writing on the inheritance of epigenetic variations, and in 2005 they co-authored the book Evolution in Four Dimensions, considered by some to be in the vanguard of an ongoing revolution within evolutionary biology.

<span class="mw-page-title-main">Biosocial criminology</span> Psychosocial examination of crime

Biosocial criminology is an interdisciplinary field that aims to explain crime and antisocial behavior by exploring biocultural factors. While contemporary criminology has been dominated by sociological theories, biosocial criminology also recognizes the potential contributions of fields such as behavioral genetics, neuropsychology, and evolutionary psychology.

Natural genetic engineering (NGE) is a class of process proposed by molecular biologist James A. Shapiro to account for novelty created in the course of biological evolution. Shapiro developed this work in several peer-reviewed publications from 1992 onwards, and later in his 2011 book Evolution: A View from the 21st Century, which has been updated with a second edition in 2022. He uses NGE to account for several proposed counterexamples to the central dogma of molecular biology. Shapiro drew from work as diverse as the adaptivity of the mammalian immune system, ciliate macronuclei and epigenetics. The work gained some measure of notoriety after being championed by proponents of Intelligent Design, despite Shapiro's explicit repudiation of that movement.

<i>A Troublesome Inheritance</i> 2014 book by Nicholas Wade

A Troublesome Inheritance: Genes, Race and Human History is a 2014 book by Nicholas Wade, a British writer, journalist, and former science and health editor for The New York Times. In the book, Wade argues that human evolution has been "recent, copious and regional" and that this has important implications for social sciences. The book has been widely denounced by the scientific community for misrepresenting research into human population genetics.

Social selection is a term used with varying meanings in biology.

Kathryn Paige Harden is an American psychologist and behavior geneticist. She is Professor of Psychology at the University of Texas at Austin, where she is also the leader of the Developmental Behavior Genetics lab and the co-director of the Texas Twin Project. She is also a Faculty Research Associate at the University of Texas at Austin's Population Research Center and a Jacobs Foundation research fellow.

<i>Blueprint</i> (Plomin book) 2018 book by behavioral geneticist Robert Plomin

Blueprint: How DNA Makes Us Who We Are is a book by behavioral geneticist Robert Plomin, first published in 2018 by the MIT Press and Allen Lane. The book argues that genetic factors, and specifically variations in individuals' DNA, have a large effect on human psychological traits, accounting for approximately half of all variation in such traits. The book also claims that genes play a more important role in people's personalities than does the environment. In Blueprint, Plomin argues that environmental effects on human psychological differences, although they exist, are "...mostly random – unsystematic and unstable – which means that we cannot do much about them."

<i>How to Be an Antiracist</i> 2019 nonfiction book by Ibram X. Kendi

How to Be an Antiracist is a 2019 nonfiction book by American author and historian Ibram X. Kendi, which combines social commentary and memoir. It was published under Random House's One World imprint. The book discusses concepts of racism and Kendi's proposals for anti-racist individual actions and systemic changes.

Fredrik deBoer is an American author.

References

  1. Harden KP (2021-09-21). The Genetic Lottery. Princeton University Press. ISBN   9780691190808 . Retrieved 2022-07-09.
  2. 1 2 Comfort N (2022-02-03). "The House Always Wins". American Scientist . Retrieved 2022-07-09.
  3. Latson J (2021-08-11). "Are Some People Born Lucky? A UT Psychologist Argues Inequality's Genetic Roots". Texas Monthly . Retrieved 2022-07-09.
  4. "Can Progressives Be Convinced That Genetics Matters?". The New Yorker . Condé Nast. 2021-09-03. Retrieved 2022-07-09.
  5. Flint J (March 2022). "Behavioral genetics in the 21st century". Current Biology . 32 (5): R202–R203. doi: 10.1016/j.cub.2022.01.051 . S2CID   247441283.
  6. Scally A (December 2021). "Reforming social genetics". Nature Ecology & Evolution . 5 (12): 1563. doi:10.1038/s41559-021-01589-8. ISSN   2397-334X. S2CID   243863447.
  7. Fletcher J (March 2022). "Backdoor to a Dead End: A Review Essay". Population and Development Review . 48 (1): 253–258. doi:10.1111/padr.12487. ISSN   0098-7921. S2CID   247459153.
  8. Cwik B (June 2022). "The Genetic Lottery: Why DNA Matters for Social Equality Kathryn Paige Harden Princeton: Princeton University Press, 2021. 320 pp. ISBN 9780691190808. $29.95 (Hardcover)". Bioethics . 36 (5): 608–609. doi:10.1111/bioe.13031. ISSN   0269-9702. S2CID   248253265.
  9. Henn BM, Merchant EK, O'Connor A, Rulli T (2021-09-21). "Why DNA Is No Key to Social Equality: On Kathryn Paige Harden's "The Genetic Lottery"". Los Angeles Review of Books . Retrieved 2022-07-09.
  10. Graves JL (January 2022). "Does it really matter if you win or lose the genetic lottery?". The Lancet . 399 (10319): 16–17. doi:10.1016/S0140-6736(21)02830-0. S2CID   245591678.
  11. Coop G, Przeworski M (February 2022). "Lottery, luck, or legacy. A review of "The Genetic Lottery: Why DNA matters for social equality"". Evolution . 76 (4): 846–853. doi:10.1111/evo.14449. PMC   9313868 . PMID   35225362. S2CID   247156853.
  12. Harden, Kathryn Paige (October 2022). "On genetics and justice: A reply to Coop and Przeworski (2022)". Evolution. 76 (10): 2469–2474. doi:10.1111/evo.14589. ISSN   0014-3820. PMC   10337657 . PMID   35913435. S2CID   251222110.
  13. Coop, Graham; Przeworski, Molly (October 2022). "Luck, lottery, or legacy? The problem of confounding. A reply to Harden". Evolution. 76 (10): 2464–2468. doi:10.1111/evo.14588. ISSN   0014-3820. PMC   9627830 . PMID   35915930.
  14. Feldman MW, Riskin J. "Why Biology Is Not Destiny". New York Review of Books . ISSN   0028-7504 . Retrieved 2022-07-09.
  15. Martschenko DO (November 2021). "Social Equality in an Alternate World". The Hastings Center Report . 51 (6): 54–55. doi:10.1002/hast.1307. PMC   9210985 . PMID   34904740.