Cadralazine

Last updated
Cadralazine
Cadralazine.svg
Cadralazine-3D-spacefill.png
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
  • Ethoxy-N'-{6-[ethyl(2-hydroxypropyl)amino]pyridazin-3-yl}carbohydrazide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C12H21N5O3
Molar mass 283.332 g·mol−1
3D model (JSmol)
  • O=C(OCC)NNc1nnc(N(CC(O)C)CC)cc1
  • InChI=1S/C12H21N5O3/c1-4-17(8-9(3)18)11-7-6-10(13-15-11)14-16-12(19)20-5-2/h6-7,9,18H,4-5,8H2,1-3H3,(H,13,14)(H,16,19) X mark.svgN
  • Key:QLTVVOATEHFXLT-UHFFFAOYSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Cadralazine is an antihypertensive of the hydrazinophthalazine chemical class. [1]

Related Research Articles

ATC code C02Antihypertensives is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. Subgroup C02 is part of the anatomical group C Cardiovascular system.

<span class="mw-page-title-main">Hydralazine</span> Anti-hypertension medication

Hydralazine, sold under the brand name Apresoline among others, is a medication used to treat high blood pressure and heart failure. This includes high blood pressure in pregnancy and very high blood pressure resulting in symptoms. It has been found to be particularly useful in heart failure, together with isosorbide dinitrate, for treatment of people of African descent. It is given by mouth or by injection into a vein. Effects usually begin around 15 minutes and last up to six hours.

<span class="mw-page-title-main">Pyridazine</span> Heterocyclic organic compound (C4H4N2)

Pyridazine is an aromatic, heterocyclic, organic compound with the molecular formula C4H4N2. It contains a six-membered ring with two adjacent nitrogen atoms. It is a colorless liquid with a boiling point of 208 °C. It is isomeric with two other diazine rings, pyrimidine and pyrazine.

<span class="mw-page-title-main">Hydrazinophthalazine</span> Drug class

Hydrazinophthalazines are a class of antihypertensive drugs including:

The molecular formula C12H21N5O3 (molar mass: 283.33 g/mol, exact mass: 283.1644 u) may refer to:

References

  1. ↑ McTavish D, Young RA, Clissold SP (October 1990). "Cadralazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of hypertension". Drugs. 40 (4): 543–60. doi:10.2165/00003495-199040040-00005. PMID   2083513.
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