Capillaria plica

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Capillaria plica
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Eukaryota
Kingdom: Animalia
Phylum: Nematoda
Class: Enoplea
Order: Enoplida
Family: Capillariidae
Genus: Capillaria
Species:
C. plica
Binomial name
Capillaria plica
Rudolphi, 1819
Synonyms

Pearsonema plica

Capillaria plica (dog bladder worm) is a parasitic nematode which is most often found in the urinary bladder, and occasionally in the kidneys, of dogs and foxes. [1] It has also been found in the domestic cat, and various wild mammals. [2] [3] Its presence usually produces no clinical symptoms, but in some cases, it leads to hematuria (blood in the urine), cystitis (inflammation of the urinary bladder), or difficulty in urination.

Contents

Taxonomy and description

This species was originally described in 1819, and named Capillaria plica. In 1982, the suggestion was made that C. plica be transferred to the genus Pearsonema Freitas & Mendonça 1960, as Pearsonema plica. [4] Currently, both names are used in the literature with roughly equal frequency. For example, searches of the PubMed database performed on 22 Nov 2008 yielded the same number of hits dated 2000 or later using either Capillaria plica or Pearsonema plica.

Hosts and distribution

Capillaria plica is often found in the urine, urinary bladder or kidneys of dogs and cats in North America, Europe, Asia and Africa. It has also been identified in the urinary bladder and kidneys of several wild mammals in North America and Europe:

Life cycle

In dogs and cats, eggs of Capillaria plica are released in the urine of the mammalian definitive host. First stage larvae (L1) develop within the eggshell in 30–36 days. When eaten by the intermediate host -- earthworms of the genera Lumbricus or Dendrobaena—the L1 larvae hatch in the earthworm's intestine. The larvae burrow through the intestinal wall and become embedded in connective tissue throughout the worm's body. If the earthworm is eaten by a suitable mammalian host, the larvae molt into second stage larvae (L2), burrow through the intestinal wall, and molt again into third stage larvae (L3). The L3 are carried through the circulatory system to the glomeruli of the kidneys. From there, they travel down the ureter to the urinary bladder. By 33 days post-infection, third (L3) and fourth-stage larvae (L4) are found in the urinary bladder. Here they mature into adults and reproduce sexually, shedding fertilized eggs into the urine of the host within about 60 days of infection. [5] Detailed life cycle studies have not been carried out with wild animal definitive hosts.

Prevalence

Prevalence rates of up to 50% in wild hosts [1] and 76% in kennel dogs [6] have been reported.

Clinical symptoms

Most infected animals exhibit no clinical symptoms. In cases of heavy infestation, symptoms may include cystitis (inflammation of the urinary bladder), mild proteinuria (protein in the urine), and hematuria (blood in the urine). Mild inflammation of the ureter has also been reported. [2]

Diagnosis and treatment

Diagnosis in cases of hematuria or cystitis is made by finding eggs in the urine sediment. Successful treatment with levamisole, ivermectin or fenbendazole has been reported. [7]

Related Research Articles

<span class="mw-page-title-main">Interstitial cystitis</span> Medical condition

Interstitial cystitis (IC), a type of bladder pain syndrome (BPS), is chronic pain in the bladder and pelvic floor of unknown cause. It is the urologic chronic pelvic pain syndrome of women. Symptoms include feeling the need to urinate right away, needing to urinate often, and pain with sex. IC/BPS is associated with depression and lower quality of life. Many of those affected also have irritable bowel syndrome and fibromyalgia.

<span class="mw-page-title-main">Urinary tract infection</span> Infection that affects part of the urinary tract

A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. When it affects the lower urinary tract it is known as a bladder infection (cystitis) and when it affects the upper urinary tract it is known as a kidney infection (pyelonephritis). Symptoms from a lower urinary tract infection include pain with urination, frequent urination, and feeling the need to urinate despite having an empty bladder. Symptoms of a kidney infection include fever and flank pain usually in addition to the symptoms of a lower UTI. Rarely the urine may appear bloody. In the very old and the very young, symptoms may be vague or non-specific.

<span class="mw-page-title-main">Bladder</span> Organ in humans and vertebrates that collects and stores urine from the kidneys before disposal

The bladder is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans, the bladder is a distensible organ that sits on the pelvic floor. Urine enters the bladder via the ureters and exits via the urethra. The typical adult human bladder will hold between 300 and 500 ml before the urge to empty occurs, but can hold considerably more.

<span class="mw-page-title-main">Cystoscopy</span> Medical procedure; endoscopy of the urinary bladder via the urethra

Cystoscopy is endoscopy of the urinary bladder via the urethra. It is carried out with a cystoscope.

<span class="mw-page-title-main">Urinalysis</span> Array of tests performed on urine

Urinalysis, a portmanteau of the words urine and analysis, is a panel of medical tests that includes physical (macroscopic) examination of the urine, chemical evaluation using urine test strips, and microscopic examination. Macroscopic examination targets parameters such as color, clarity, odor, and specific gravity; urine test strips measure chemical properties such as pH, glucose concentration, and protein levels; and microscopy is performed to identify elements such as cells, urinary casts, crystals, and organisms.

<span class="mw-page-title-main">Hematuria</span> Medical condition

Hematuria or haematuria is defined as the presence of blood or red blood cells in the urine. "Gross hematuria" occurs when urine appears red, brown, or tea-colored due to the presence of blood. Hematuria may also be subtle and only detectable with a microscope or laboratory test. Blood that enters and mixes with the urine can come from any location within the urinary system, including the kidney, ureter, urinary bladder, urethra, and in men, the prostate. Common causes of hematuria include urinary tract infection (UTI), kidney stones, viral illness, trauma, bladder cancer, and exercise. These causes are grouped into glomerular and non-glomerular causes, depending on the involvement of the glomerulus of the kidney. But not all red urine is hematuria. Other substances such as certain medications and foods can cause urine to appear red. Menstruation in women may also cause the appearance of hematuria and may result in a positive urine dipstick test for hematuria. A urine dipstick test may also give an incorrect positive result for hematuria if there are other substances in the urine such as myoglobin, a protein excreted into urine during rhabdomyolysis. A positive urine dipstick test should be confirmed with microscopy, where hematuria is defined by three or more red blood cells per high power field. When hematuria is detected, a thorough history and physical examination with appropriate further evaluation can help determine the underlying cause.

Dysuria refers to painful or uncomfortable urination.

<span class="mw-page-title-main">Feline lower urinary tract disease</span> Any disorder affecting the bladder or urethra of cats

Feline lower urinary tract disease (FLUTD) is a generic category term to describe any disorder affecting the bladder or urethra of cats.

<span class="mw-page-title-main">Hemorrhagic cystitis</span> Medical condition

Hemorrhagic cystitis or haemorrhagic cystitis is an inflammation of the bladder defined by lower urinary tract symptoms that include dysuria, hematuria, and hemorrhage. The disease can occur as a complication of cyclophosphamide, ifosfamide and radiation therapy. In addition to hemorrhagic cystitis, temporary hematuria can also be seen in bladder infection or in children as a result of viral infection.

<i>Dioctophyme renale</i> Species of roundworm

Dioctophyme renale, commonly referred to as the giant kidney worm, is a parasitic nematode (roundworm) whose mature form is found in the kidneys of mammals. D. renale is distributed worldwide, but is less common in Africa and Oceania. It affects fish eating mammals, particularly mink and dogs. Human infestation is rare, but results in kidney destruction, usually of one kidney and hence not fatal. A 2019 review listed a total of 37 known human cases of dioctophymiasis in 10 countries with the highest number (22) in China. Upon diagnosis through tissue sampling, the only treatment is surgical excision.

Urologic diseases or conditions include urinary tract infections, kidney stones, bladder control problems, and prostate problems, among others. Some urologic conditions do not affect a person for that long and some are lifetime conditions. Kidney diseases are normally investigated and treated by nephrologists, while the specialty of urology deals with problems in the other organs. Gynecologists may deal with problems of incontinence in women.

<i>Capillaria aerophila</i> Species of roundworm

Capillaria aerophila is a nematode parasite found in the respiratory tract of foxes, dogs, and various other carnivorous mammals. A few cases of human infestation have also been reported. Though it is sometimes called a "lungworm", this term usually refers to other species of nematodes. Infestation by C. aerophila is referred to as "pulmonary capillariasis", "bronchial capillariasis," or (rarely) "thominxosis." This parasite has a direct life cycle, meaning that the life cycle can be completed in a single host. C. aerophila usually causes only minor clinical symptoms, such as irritation of the respiratory tract and coughing. However, secondary bacterial infections of the respiratory tract, including pneumonia, may develop in heavy infestations. Treatment with anthelmintics, such as levamisole or fenbendazole, is usually sufficient to cure C. aerophila infestations.

<i>Capillaria <span style="font-style:normal;">(nematode)</span></i> Genus of roundworms

Capillaria is a genus of nematodes in the family Capillariidae .

Feline idiopathic cystitis (FIC) or feline interstitial cystitis or cystitis in cats, is one of the most frequently observed forms of feline lower urinary tract disease (FLUTD). Feline cystitis means "inflammation of the bladder in cats". The term idiopathic means unknown cause; however, certain behaviours have been known to aggravate the illness once it has been initiated. It can affect both males and females of any breed of cat. It is more commonly found in female cats; however, when males do exhibit cystitis, it is usually more dangerous.

<span class="mw-page-title-main">Cystitis cystica</span> Medical condition

Cystitis cystica is an uncommon chronic reactive inflammatory disease that is believed to be brought on by a tumor, calculi, infection, or obstruction of the urothelium. Cystitis glandularis is a proliferative progression of cystitis cystica that is distinguished by urothelial glandular metaplasia.

<span class="mw-page-title-main">Eosinophilic cystitis</span> Medical condition

Eosinophilic cystitis is a rare type of interstitial cystitis first reported in 1960 by Edwin Brown. Eosinophilic cystitis has been linked to a number of etiological factors, including allergies, bladder tumors, trauma to the bladder, parasitic infections, and chemotherapy drugs, though the exact cause of the condition is still unknown. The antigen-antibody response is most likely the cause of eosinophilic cystitis. This results in the generation of different immunoglobulins, which activate eosinophils and start the inflammatory process.

<span class="mw-page-title-main">Emphysematous cystitis</span> Medical condition

Emphysematous cystitis is a rare type of infection of the bladder wall by gas-forming bacteria or fungi. The most frequent offending organism is E. coli. Other gram negative bacteria, including Klebsiella and Proteus are also commonly isolated. Fungi, such as Candida, have also been reported as causative organisms. Citrobacter and Enterococci have also been found to cause emphysematous cystitis. Although it is a rare type of bladder infection, it is the most common type of all gas-forming bladder infections. The condition is characterized by the formation of air bubbles in and around the bladder wall. The gas found in the bladder consists of nitrogen, hydrogen, oxygen, and carbon dioxide. The disease most commonly affects elderly diabetic and immunocompromised patients. The first case was identified in a post-mortem examination in 1888.

<i>Capillaria feliscati</i> Species of roundworm

Capillaria feliscati (also known as Pearsonema feliscati, the cat bladder worm is a worm that affects cats, and seldom dogs. Its main final hosts are wild carnivores. It is a urinary tract nematode, though its occurrence is rare. C. feliscati are small, delicate, yellowish, thread-like worms. Adults are approximately between 16 and 53 millimetres in length.

<span class="mw-page-title-main">Cat worm infections</span> Worm infections in cats

Cat worm infections, the infection of cats (Felidae) with parasitic worms, occur frequently. Most worm species occur worldwide in both domestic and other cats, but there are regional, species and lifestyle differences in the frequency of infestation. According to the classification of the corresponding parasites in the zoological system, infections can be divided into those caused by nematode and flatworms - in the case of the latter, mainly cestoda and trematoda - while other strains are of no veterinary significance. While threadworms usually do not require an intermediate host for their reproduction, the development cycle of flatworms always proceeds via alternate hosts.

<span class="mw-page-title-main">Nematode infection in dogs</span> Threadworm infections of dogs are frequent

Nematode infection in dogs - the infection of dogs with parasitic nemamotodes - are, along with tapeworm infections and infections with protozoa, frequent parasitoses in veterinary practice. Nematodes, as so-called endoparasites, colonize various internal organs - most of them the digestive tract - and the skin. To date, about 30 different species of nematode have been identified in domestic dogs; they are essentially also found in wild dog species. However, the majority of them often cause no or only minor symptoms of disease in adult animals. The infection therefore does not necessarily have to manifest itself in a worm disease (helminthosis). For most nematodes, an infection can be detected by examining the feces for eggs or larvae. Roundworm infection in dogs and the hookworm in dogs is of particular health significance in Central Europe, as they can also be transmitted to humans (zoonosis). Regular deworming can significantly reduce the frequency of infection and thus the risk of infection for humans and dogs.

References

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