Chad Mirkin | |
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Born | Phoenix, Arizona, U.S. | November 23, 1963
Alma mater | Dickinson College, Pennsylvania State University |
Awards | Lemelson-MIT Prize, 2009; Linus Pauling Award, 2013; Raymond and Beverly Sackler Prize in Convergence Research, 2015; Dan David Prize, 2016; Wilhelm Exner Medal, 2017; William H. Nichols Medal Award, 2017; Kabiller Prize, 2019; Perkin Medal 2019; AAAS Philip Hauge Abelson Prize 2020; King Faisal Prize 2023 |
Scientific career | |
Fields | Chemistry, Materials science, and Nanotechnology |
Institutions | Northwestern University |
Notable students |
External videos | |
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"Nanotechnology: Moving Beyond Small Thinking", Chad Mirkin, Air Force Office of Scientific Research (AFOSR) |
Chad Alexander Mirkin (born November 23, 1963) is an American chemist. He is the George B. Rathmann professor of chemistry, professor of medicine, professor of materials science and engineering, professor of biomedical engineering, and professor of chemical and biological engineering, and director of the International Institute for Nanotechnology and Center for Nanofabrication and Molecular Self-Assembly at Northwestern University. [2]
Mirkin is known for his development of nanoparticle-based biodetection schemes, the invention of dip-pen nanolithography (recognized by National Geographic as one of the top 100 scientific discoveries that changed the world), and contributions to supramolecular chemistry, nanoelectronics, and nanooptics. In 2010, he was listed as the most cited chemist in the world over the last decade in terms of total citations, the second highest most cited chemist [3] in terms of impact factor, [4] and the top most cited nanomedicine researcher. [5]
Mirkin was born November 23, 1963, in Phoenix, Arizona. [6] He received his B.S. degree from Dickinson College in 1986 and his PhD from Penn State University in 1989. [2] [7] He was a NSF postdoctoral research fellow at Massachusetts Institute of Technology where he worked with Professor Mark S. Wrighton on microelectrode devices for electrocatalysis. [8] He became a professor at Northwestern University in 1991. [7]
The focus of Mirkin's research is on developing methods for controlling the architecture of molecules and materials on the 1 – 100 nm length scale and utilizing such structures in the development of analytical tools that can be used in the areas of chemical and biological sensing, lithography, catalysis, and optics. Mirkin has pioneered the use of DNA and nanoparticles as synthons in materials science and the development of nanoparticle-based biodiagnostics. [2] [7]
A common strategy used by Mirkin's group is the use of the unique properties of spherical nucleic acids (SNAs), spherical arrangements of nucleic acids with or without organic or inorganic nanoparticle cores, to enable the synthesis of novel materials and colloidal crystals, the development of high sensitivity probes for chemical and medical diagnostic purposes, and single-entity structures capable of intracellular gene regulation. His 1996 work with SNA-gold nanoparticle conjugates introduced the concept of a nanoparticle as an atom and nucleic acids as bonds, and it laid the ground work for the fields of colloidal crystal engineering with DNA and molecular diagnostics based upon well-defined nanoparticle and nanocrystal bioconjugates. SNAs are the cornerstone of Luminex's FDA-cleared Verigene system (now used in over half of the world's top hospitals), EMD Millipore's SmartFlare platform (licensed to AuraSense, Inc. and Holden Pharma), and seven drugs in human clinical trials. In addition, his inventions of DPN, Polymer Pen Lithography (PPL), and Beam Pen Lithography (BPL) are the basis for the TERA-fab M and E series commercial patterning tools, known as desktop fabs (TERA-print, LLC).
He has published over 870 manuscripts, with a Google Scholar H-index of 202, [9] and has over 1200 patents and patent applications. [10]
Mirkin has been elected into all three branches of the National Academies of Sciences, Engineering, and Medicine, the 10th person so honored. [11] He has served on several editorial advisory boards, including ACS Nano, the Journal of the American Chemical Society and Angewandte Chemie. He is the founding editor of the nanotechnology journal Small, and he is an associate editor of the Journal of the American Chemical Society. [12] Mirkin is a co-founder of multiple companies, including NanoInk, [13] Nanosphere (acquired by Luminex for $83M in 2016 [14] ), Azul 3D, [15] TERA-print, [16] Exicure, [17] and Stoicheia. [18]
Information scientists at CAS, a division of the American Chemical Society, singled out Mirkin and his contributions to supramolecular chemistry and nanomaterials in an article about potential future winners of the Nobel Prize in Chemistry, saying that “Overall, Mirkin’s work set up the foundation of modern nanotechnology and development of related diagnostic, therapeutic, and material applications.” [19]
In addition to his academic and research work, Mirkin has been involved in shaping science policy decisions. From 2009 to 2017 Mirkin was appointed to President Barack Obama's President's Council of Advisors on Science and Technology (PCAST). [20] [21] He co-chaired the PCAST report titled, "Engage to Excel," focusing on teaching and engagement issues involving students who are in their first two years of undergraduate study at R-1, 2 and 4-year institutions, and community colleges. [22]
Craig Jon Hawker is an Australian-born chemist. His research has focused on the interface between organic and polymer chemistry, with emphasis on the design, synthesis, and application of well-defined macromolecular structures in biotechnology, microelectronics, and surface science. Hawker holds more than 45 U.S. patents, and he has co-authored over 300 papers in the areas of nanotechnology, materials science, and chemistry. He was listed as one of the top 100 most cited chemists worldwide over the decade 1992–2002, and again in 2000–2010.
Mostafa A. El-Sayed is an Egyptian-American physical chemist, nanoscience researcher, member of the National Academy of Sciences and US National Medal of Science laureate. He is known for the spectroscopy rule named after him, the El-Sayed rule.
George McClelland Whitesides is an American chemist and professor of chemistry at Harvard University. He is best known for his work in the areas of nuclear magnetic resonance spectroscopy, organometallic chemistry, molecular self-assembly, soft lithography, microfabrication, microfluidics, and nanotechnology. A prolific author and patent holder who has received many awards, he received the highest Hirsch index rating of all living chemists in 2011.
Tobin Jay Marks is an inorganic chemistry Professor, the Vladimir N. Ipatieff Professor of Catalytic Chemistry, Professor of Material Science and Engineering, Professor of Chemical and Biological Engineering, and Professor of Applied Physics at Northwestern University in Evanston, Illinois. Among the themes of his research are synthetic organo-f-element and early-transition metal organometallic chemistry, polymer chemistry, materials chemistry, homogeneous and heterogeneous catalysis, molecule-based photonic materials, superconductivity, metal-organic chemical vapor deposition, and biological aspects of transition metal chemistry.
John William White FAIP FRACI was an Australian chemist who was Professor of Physical and Theoretical Chemistry, Research School of Chemistry, at the Australian National University.
George Chappell Schatz, the Morrison Professor of Chemistry at Northwestern University, is a theoretical chemist best known for his seminal contributions to the fields of reaction dynamics and nanotechnology.
Vladimir Haensel was an American chemical engineer who invented the platforming process - a platinum catalytic process for reforming petroleum hydrocarbons into gasoline. In addition, he was influential in the creation of catalytic converters for automobiles.
Joseph M. DeSimone is an American chemist, inventor, and entrepreneur who has co-founded companies based on his research, including the American 3D printing technology company, Carbon, of which he was CEO from 2014 until November 2019.
Didier Astruc carried out his studies in chemistry in Rennes. After a Ph. D. with professor R. Dabard in organometallic chemistry, he did post-doctoral studies with professor R. R. Schrock at the Massachusetts Institute of Technology Cambridge, Massachusetts, in the U.S. and later a sabbatical year with professor K. P. C. Vollhardt at the University of California at Berkeley. He became a CNRS Director of research in Rennes, then in 1983 full Professor of Chemistry at the University Bordeaux 1. He is known for his work on electron-reservoir complexes and dendritic molecular batteries, catalytic processes using nanoreactors and molecular recognition using gold nanoparticles and metallodendrimers. He is the author of three books, scientific publications and the editor of five books or special issues. He has been a member of the National CNRS committee from 2000 to 2008 and the President of the Coordination Chemistry Division of the Société Française de Chimie from 2000 to 2004. Didier Astruc is on the Thompson-Reuters list of the top 100 chemists who have achieved the highest citation impact scores for their chemistry papers published between 2000 and 2010. and on the list of the Highest Cited Researchers 2015 and 2016 (Thomson-Reuters). and 2017 to 2023
Ayyappanpillai Ajayaghosh is a research scientist/academician in the domain of interdisciplinary chemistry, and the former Director of the National Institute for Interdisciplinary Science and Technology. He is known for his studies on supramolecular assemblies, organogels, photoresponsive materials, chemosensory and security materials systems and is an elected fellow of all the three major Indian science academies viz. the National Academy of Sciences, India, Indian National Science Academy and the Indian Academy of Sciences as well as The World Academy of Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Chemical Sciences in 2007. He is the first chemist to receive the Infosys Science Prize for physical sciences, awarded by the Infosys Science Foundation. He received the TWAS Prize of The World Academy of Sciences in 2013 and the Goyal prize in 2019.
Nicholas A. Kotov is the Irving Langmuir Distinguished Professor of Chemical Sciences and Engineering at the University of Michigan in Ann Arbor, MI, USA. Prof. Nicholas Kotov demonstrated that the ability to self-organize into complex structures is the unifying property of all inorganic nanostructures. He has developed a family of bioinspired composite materials with a wide spectrum of properties that were previously unattainable in classical materials. These composite biomimetic materials are exemplified by his nacre-like ultrastrong yet transparent composites, enamel-like, stiff yet vibration-isolating composites, and cartilage-like membranes with both high strength and ion conductance.
Teri W. Odom is an American chemist and materials scientist. She is the chair of the chemistry department, the Joan Husting Madden and William H. Madden, Jr. Professor of Chemistry, and a professor of materials science and engineering at Northwestern University. She is affiliated with the university's International Institute for Nanotechnology, Chemistry of Life Processes Institute, Northwestern Initiative for Manufacturing Science and Innovation, Interdisciplinary Biological Sciences Graduate Program, and department of applied physics.
The International Institute for Nanotechnology (IIN) was established by Northwestern University in 2000. It was the first institute of its kind in the United States and is one of the premier nanoscience research centers in the world. Today, the IIN represents and unites more than $1 billion in nanotechnology research, educational programs, and supporting infrastructure.
Pierangelo Metrangolo is an Italian chemist with interests in supramolecular chemistry and functional materials. He also has an interest in crystal engineering, in particular by using the halogen bond. He is Vice-President and President-Elect of the Physical and Biophysical Chemistry Division of IUPAC.
George Christou is a British-American chemist, currently the Drago and Distinguished Professor at the University of Florida, previously the Earl Blough Professor at the Indiana University. He is also an Honorary Professor at London Centre for Nanotechnology. His current interests are in bioinorganic chemistry, materials and nanoscale magnets, and supramolecular and cluster chemistry. He was a pioneer of the field of single-molecule magnets and has been a significant figure in inorganic chemistry, with multiple papers each cited over 100 times. He has published over 600 peer-reviewed publications, with an H index of 96, and has been selected to both the Highly Cited Researchers 2014 and 2015 lists. He has received a variety of awards and honours over the years, including the recent American Chemical Society 2019 ACS Award in Inorganic Chemistry, the 2017 SEC Faculty Achievement Award, the 2016 Southern Chemist Award, and the 2016 Nyholm Prize of the UK Royal Society of Chemistry. He was named one of 15 Florida Most Influential Scientists.
Christy Lynn Haynes is a chemist at the University of Minnesota. She works at the interface of analytical, biological, and nanomaterials chemistry.
Jill Millstone is a professor of chemistry at the University of Pittsburgh. She works on metal-ligand chemistry in nanoparticle synthesis. She is the American Chemical Society Kavli Foundation Emerging Leader in Chemistry Lecturer for 2018.
Nathan C. Gianneschi is the Jacob & Rosaline Cohn Professor of Chemistry, Materials Science & Engineering, and Biomedical Engineering at Northwestern University and the Associate Director for the International Institute for Nanotechnology. Gianneschi's lab takes an interdisciplinary approach to nanomaterials research, with a focus on multifunctional materials for biomedical applications, programmed interactions with biomolecules and cells, and basic research into nanoscale materials design, synthesis and characterization.
So-Jung Park 박소정(朴昭靜) is a professor of chemistry at Ewha Womans University, Republic of Korea. Her research considers the self-assembly of nanoparticles and functional molecules for biomedical and optoelectronic devices. She serves as Associate Editor of ACS Applied Materials & Interfaces and Nanoscale.
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