Fraxetin

Last updated
Fraxetin
Fraxetin.svg
Names
Preferred IUPAC name
7,8-Dihydroxy-6-methoxy-2H-1-benzopyran-2-one
Other names
7,8-Dihydroxy-6-methoxycoumarin
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.008.525 OOjs UI icon edit-ltr-progressive.svg
EC Number
  • 209-376-2
KEGG
PubChem CID
UNII
  • InChI=1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3
    Key: HAVWRBANWNTOJX-UHFFFAOYSA-N
  • InChI=1/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3
    Key: HAVWRBANWNTOJX-UHFFFAOYAM
  • COC1=C(C(=C2C(=C1)C=CC(=O)O2)O)O
Properties
C10H8O5
Molar mass 208.169 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Fraxetin is an O-methylated coumarin. It can be found in Fraxinus rhynchophylla [1] and seeds of Datura stramonium . [2] Fraxin is a glucoside of fraxetin.

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References

  1. Thuong, PT; Pokharel, YR; Lee, MY; Kim, SK; Bae, K; Su, ND; Oh, WK; Kang, KW (2009). "Dual anti-oxidative effects of fraxetin isolated from Fraxinus rhinchophylla". Biological & Pharmaceutical Bulletin. 32 (9): 1527–32. doi: 10.1248/bpb.32.1527 . PMID   19721227.
  2. Li J, Lin B, Wang G, Gao H, Qin M (February 2012). "[Chemical constituents of Datura stramonium seeds]". Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica (in Chinese). 37 (3): 319–22. PMID   22568232.