The Semantic Web, sometimes known as Web 3.0, is an extension of the World Wide Web through standards set by the World Wide Web Consortium (W3C). The goal of the Semantic Web is to make Internet data machine-readable.
In information science, an ontology encompasses a representation, formal naming, and definitions of the categories, properties, and relations between the concepts, data, or entities that pertain to one, many, or all domains of discourse. More simply, an ontology is a way of showing the properties of a subject area and how they are related, by defining a set of terms and relational expressions that represent the entities in that subject area. The field which studies ontologies so conceived is sometimes referred to as applied ontology.
A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the order of the four bases: G (guanine), C (cytosine), A (adenine) and T (thymine). This is then reported as a text string, called a read. Some DNA sequencers can be also considered optical instruments as they analyze light signals originating from fluorochromes attached to nucleotides.
F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth-largest pharmaceutical company in the world by revenue and the leading provider of cancer treatments globally.
QIAGEN is a provider of sample and assay technologies for molecular diagnostics, applied testing, academic and pharmaceutical research. The company operates in more than 35 offices in over 25 countries. QIAGEN N.V., the global corporate headquarter of the QIAGEN group, is located in Venlo, The Netherlands. European, American, and Asian regional headquarters are located in respectively Hilden, Germany; Germantown, Maryland United States; and Shanghai, China. QIAGEN's shares are listed at the NYSE and at the Frankfurt Stock Exchange in the Prime Standard. Thierry Bernard is the company's Chief Executive Officer(CEO). The main operative headquarters are located in Hilden, Germany.
Ontotext is a software company with offices in Europe and USA. It is the semantic technology branch of Sirma Group. Its main domain of activity is the development of software based on the Semantic Web languages and standards, in particular RDF, OWL and SPARQL. Ontotext is best known for the Ontotext GraphDB semantic graph database engine. Another major business line is the development of enterprise knowledge management and analytics systems that involve big knowledge graphs. Those systems are developed on top of the Ontotext Platform that builds on top of GraphDB capabilities for text mining using big knowledge graphs.
BIOVIA is a software company headquartered in the United States, with representation in Europe and Asia. It provides software for chemical, materials and bioscience research for the pharmaceutical, biotechnology, consumer packaged goods, aerospace, energy and chemical industries.
In computer science, the semantic desktop is a collective term for ideas related to changing a computer's user interface and data handling capabilities so that data are more easily shared between different applications or tasks and so that data that once could not be automatically processed by a computer could be. It also encompasses some ideas about being able to share information automatically between different people. This concept is very much related to the Semantic Web, but is distinct insofar as its main concern is the personal use of information.
Mostafa Ronaghi is an Iranian molecular biologist, specializing in DNA sequencing methodology. He earned his Ph.D. from the Royal Institute of Technology in Sweden in 1998.
NEPOMUK is an open-source software specification that is concerned with the development of a social semantic desktop that enriches and interconnects data from different desktop applications using semantic metadata stored as RDF. Between 2006 and 2008 it was funded by a European Union research project of the same name that grouped together industrial and academic actors to develop various Semantic Desktop technologies.
Convera was formed in December 2000 by the merger of Intel's Interactive Services division and Excalibur Technologies Corporation. Until 2007, Convera's primary focus was the enterprise search market through its flagship product, RetrievalWare, which is widely used within the secure government sector in the United States, UK, Canada and a number of other countries. Convera sold its enterprise search business to FAST Search & Transfer in August 2007 for $23 million, at which point RetrievalWare was officially retired. Microsoft Corporation continues to maintain RetrievalWare for its existing customer base.
Biovista Inc. is a private drug development services company based in Charlottesville, Virginia, US. Biovista's core business activities include drug repositioning and drug de-risking as well as disease cohort analysis, adverse event prediction and clinical hold analysis services. Biovista is also applying its technology platform to develop its own drug repositioning programs in the areas of central nervous system (CNS), diabetes/obesity, eye disorders, and oncology.
BORO is an approach to developing ontological or semantic models for large complex operational applications that consists of a top ontology as well as a process for constructing the ontology. It was originally developed as a method for mining ontologies from multiple legacy systems – as the first stage in an architectural transformation or software modernization. It has also been used to enable semantic interoperability between legacy systems. It is described in detail in. It is the analysis method used in the development and maintenance of the U.S. Department of Defense Architecture Framework (DoDAF) Meta Model (DM2), where a data modeling working group of over 350 members was able to systematically resolve a broad spectrum of knowledge representation issues.
Model Driven Interoperability (MDI) is a methodological framework, which provides a conceptual and technical support to make interoperable enterprises using ontologies and semantic annotations, following model driven development (MDD) principles.
Amneal Pharmaceuticals, Inc. is an American publicly traded generics and specialty pharmaceutical company. The company is headquartered in Bridgewater, New Jersey.
Open PHACTS was a European initiative public–private partnership between academia, publishers, enterprises, pharmaceutical companies and other organisations working to enable better, cheaper and faster drug discovery. It has been funded by the Innovative Medicines Initiative, selected as part of three projects to "design methods for common standards and sharing of data for more efficient drug development and patient treatment in the future".
The High-performance Integrated Virtual Environment (HIVE) is a distributed computing environment used for healthcare-IT and biological research, including analysis of Next Generation Sequencing (NGS) data, preclinical, clinical and post market data, adverse events, metagenomic data, etc. Currently it is supported and continuously developed by US Food and Drug Administration, George Washington University, and by DNA-HIVE, WHISE-Global and Embleema. HIVE currently operates fully functionally within the US FDA supporting wide variety (+60) of regulatory research and regulatory review projects as well as for supporting MDEpiNet medical device postmarket registries. Academic deployments of HIVE are used for research activities and publications in NGS analytics, cancer research, microbiome research and in educational programs for students at GWU. Commercial enterprises use HIVE for oncology, microbiology, vaccine manufacturing, gene editing, healthcare-IT, harmonization of real-world data, in preclinical research and clinical studies.
The Open Semantic Framework (OSF) is an integrated software stack using semantic technologies for knowledge management. It has a layered architecture that combines existing open source software with additional open source components developed specifically to provide a complete Web application framework. OSF is made available under the Apache 2 license.
The INTEROP V-Lab is a network of organizations, which links scientists, research centers, representatives of industry, and small and medium-sized enterprises. The members come from several European countries as well as China and represent 250 scientists and 70 organizations.
Liminal BioSciences Inc., formerly known as Prometic Life Sciences Inc., is a Canadian biopharmaceutical company.
