159 may refer to:
- 159 (year)
- 159 (number), the natural number following 158 and preceding 160
- UFC 159, a mixed martial arts event held by the Ultimate Fighting Championship
- Alfa Romeo 159, a compact executive car
- Alfa Romeo 159, a Grand Prix racing car
- 159 series, an electric multiple unit rain type
- Lectionary 159, a Greek manuscript of the New Testament
This disambiguation page lists articles associated with the same number.
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