| Third edition of the Challenge Desgrange-Colombo | |
| Details | |
|---|---|
| Dates | 18 March – 22 October |
| Location | Europe |
| Races | 10 |
| Champions | |
| Individual champion |  Ferdinand Kübler (SUI) (Fréjus) |
| Nations' champion |  Italy |
The 1950 Challenge Desgrange-Colombo was the third edition of the Challenge Desgrange-Colombo. It included ten races: all the races form the 1949 edition were retained with no additions.
| Date | Race | Country | Winner | Team | Report |
|---|---|---|---|---|---|
| 18 March | Milan–San Remo | Italy | Gino Bartali (ITA) | Bartali–Gardiol | Report |
| 2 April | Tour of Flanders |  Belgium | Fiorenzo Magni (ITA) | Ganna | Report |
| 9 April | Paris–Roubaix |  France | Fausto Coppi (ITA) | Bianchi–Ursus | Report |
| 16 April | Paris–Brussels | France/ Belgium | Rik Van Steenbergen (BEL) | Mercier–Hutchinson | Report |
| 1 May | La Flèche Wallonne | Belgium | Fausto Coppi (ITA) | Bianchi–Ursus | Report |
| 7 May | Paris–Tours | France | André Mahé (FRA) | Stella–Dunlop | Report |
| 24 May – 13 June | Giro d'Italia | Italy | Hugo Koblet (SUI) | Guerra–Ursus | Report |
| 24 June – 1 July | Tour de Suisse | Switzerland | Hugo Koblet (SUI) | Guerra–Ursus | Report |
| 13 July – 7 August | Tour de France | France | Ferdinand Kübler (SUI) | Switzerland | Report |
| 22 October | Giro di Lombardia | Italy | Renzo Soldani (ITA) | Thomann | Report |
| Cyclist | Team | Points | |
|---|---|---|---|
| 1 | Ferdinand Kübler (SUI) | 89 | |
| 2 | Fiorenzo Magni (ITA) | 68 | |
| 3 | Hugo Koblet (SUI) | 60 | |
| 4 | Fausto Coppi (ITA) | 56 | |
| 5 | Gino Bartali (ITA) | 54 | |
| 6 | Raymond Impanis (BEL) | 36 | |
| 7 |  Jean Kirchen (LUX) | 35 | |
| 8 | Stan Ockers (BEL) | 34 | |
| 9= | Louison Bobet (FRA) | 32 | |
| 9= | Guy Lapébie (FRA) | 32 |
| Nation | Points | |
|---|---|---|
| 1 | Italy | 420 |
| 2 | France | 349 |
| 3 | Belgium | 300 |