Michael Kohlmann and Alexander Waske were the defending champions, but chose not to participate that year.
Luis Horna and Potito Starace were the defending champions, but lost in the first round to James Cerretani and Victor Hănescu.
Paul Hanley and Jordan Kerr were the defending champions, but lost in the quarterfinals to Philipp Petzschner and Alexander Peya.
Mikhail Youzhny and Mischa Zverev were the defending champions, but Youzhny chose not to participate, and only Zverev competed that year.
Zverev partnered with Nicolas Kiefer, but they withdrew before their semifinal match against Andreas Beck and Marco Chiudinelli, due to an abdominal muscle tear for Kiefer.
Bob Bryan and Mike Bryan were the defending champions, but decided not to participate.
Scott Lipsky and Rajeev Ram won this tournament after defeating Christopher Kas and Alexander Peya 4–6, 6–4, [10–3] in the final.
The 2011 Strabag Prague Open was a professional tennis tournament played on clay courts. It was the 18th edition of the men's tournament which was part of the 2011 ATP Challenger Tour and the 10th edition of the women's tournament, part of 2011 ITF Women's Circuit. It was part of the WTA Tour in the previous year, but was degraded to ITF event this year. It took place in Prague, Czech Republic between 2 and 8 May 2011.
Carlos Berlocq and Eduardo Schwank were the defending champions, but decided not to participate.
Jürgen Melzer and Philipp Petzschner defeated Marcel Granollers and Marc López in the final, 6–3, 6–4.
Marc López and David Marrero were the defending champions, but lost in the first round to Andreas Beck and Christopher Kas.
Johan Brunström and Jarkko Nieminen were the defending champions, but Nieminen decided not to participate.
Brunström played alongside Adil Shamasdin, but they were eliminated in the semifinals by Kas and Peya.
Dustin Brown and Rogier Wassen were the defending champions, but decided not to participate together.
Brown plays alongside Michael Kohlmann, while Wassen partners up with Lukáš Rosol. Brown lost in the first round to Santiago Giraldo and Pere Riba and Wassen lost in the second round to Franco Ferreiro and André Sá.
Robert Lindstedt and Horia Tecău were the defending champions, but Lindstedt chose not to participate.
Tecău partnered with Lukáš Dlouhý, but were eliminated in the quarterfinals by Santiago González and Jamie Murray.
Jonathan Erlich and Andy Ram won the title, defeating Christopher Kas and Alexander Peya 7–6(7–2), 6–4 in the final.
Dustin Brown and Rogier Wassen were the defending champions, but decided not to participate.
Jamie Murray and André Sá won the title, defeating Lukáš Dlouhý and Marcelo Melo 6–4, 7–6(9–7) in the final.
Eric Butorac and Jean-Julien Rojer were the defending champions but were eliminated in the second round by Robin Haase and Viktor Troicki. Andy Murray and Jamie Murray won the title after beating František Čermák and Filip Polášek 6–1, 6–4 in the final.
Bob Bryan and Mike Bryan were the defending champions but decided to participate at Valencia instead.
Michaël Llodra and Nenad Zimonjić won the title, defeating Max Mirnyi and Daniel Nestor in the final.
Marcel Granollers and Tommy Robredo were the defending champions but decided not to participate.
Bob and Mike Bryan were the three-time defending champions, but lost to the unseeded pair Leander Paes and Radek Štěpánek, 7–6(7–1), 6–2, in the final. With this win Paes completed the career grand slam in Men's doubles.
Santiago González and Scott Lipsky were the defending champions but decided not to participate together.
González partnered up with Christopher Kas but lost in the Quarterfinals, while Lipsky played alongside Rajeev Ram but lost in the first round.
Mariusz Fyrstenberg and Marcin Matkowski won the tournament defeating Marcel Granollers and Marc López in the final.
Simone Bolelli and Horacio Zeballos were the defending champions but decided not to participate. Bolelli entered the Estoril Open instead, while Zeballos competes in the Tunis Open.
František Čermák and Filip Polášek won the tournament defeating Xavier Malisse and Dick Norman 6–4, 7–5 in the final.
Bob Bryan and Mike Bryan were the defending champions but decided not to participate.
Andre Begemann and Martin Emmrich won the title, defeating Julian Knowle and Filip Polášek 6–4, 3–6, [10–4] in the final.
Christopher Kas and Philipp Kohlschreiber were the defending champions, but they lost in semifinals to Tomáš Berdych and Jan Hájek.
Berdych and Hájek went on to win the title, defeating Alexander Peya and Bruno Soares in the final, 6–2, 6–4.
František Čermák 
Christopher Kas 
Alexander Peya 
