Ariel Behar and Horacio Zeballos were the defending champions but decided not to participate.
Marcelo Demoliner and Franko Škugor won the final 7–6(10–8), 6–2 against Sergio Galdós and Marco Trungelliti.
Guilherme Clezar was the defending champion, but lost to James Duckworth in the quarterfinals.
Rajeev Ram won the tournament by defeating André Ghem 4–6, 6–4, 6–3 in the final.
Marcelo Demoliner and João Souza were the defending champions but lost to Thiemo de Bakker and André Sá in the final 6–3, 6–2.
This was the first edition of the tournament.
Jérémy Chardy and Łukasz Kubot were the defending champions, but they chose to compete in Hamburg instead.
Guillermo Durán and Andrés Molteni were the defending champions but only Molteni chose to defend his title, partnering Guido Andreozzi. Molteni lost in the first round to Franco Agamenone and Federico Zeballos.
Juan Sebastián Cabal and Robert Farah were the defending champions, but lost in the final to Pablo Carreño Busta and Pablo Cuevas, 4–6, 7–5, [8–10].
Bob and Mike Bryan were the defending champions, but chose not to participate this year.
Pierre-Hugues Herbert and Nicolas Mahut were the two-time defending champions, but retired in the first round against Marcus Daniell and Marcelo Demoliner.
The doubles event at the 2017 Milo Open Cali was won by Marcelo Arévalo and Miguel Ángel Reyes-Varela. Nicolás Jarry and Hans Podlipnik-Castillo were the defending champions but chose not to defend their title and did not participate in the 2017 event. Arévalo and Reyes-Varela won the title after defeating Sergio Galdós and Fabrício Neis 6–3, 6–4 in the final.
Ariel Behar and Fabiano de Paula were the defending champions but chose to defend their title with different partners. Behar partnered Attila Balázs but lost in the semifinals to Marcelo Arévalo and Miguel Ángel Reyes-Varela. De Paula partnered Sergio Galdós but lost in the first round to Hugo Dellien and Federico Zeballos.
Andrés Molteni and Diego Schwartzman were the defending champions but only Molteni chose to defend his title, partnering Sergio Galdós. Molteni lost in the first round to Pedro Cachín and Nicolás Jarry.
Julio Peralta and Horacio Zeballos were the defending champions but chose not to defend their title.
This was the first edition of the tournament.
Ariel Behar and Fabiano de Paula were the defending champions but chose not to defend their title.
Łukasz Kubot and Marcelo Melo were the two-time defending champions, but lost in the final to Raven Klaasen and Michael Venus, 6–4, 3–6, [4–10].
Marcelo Demoliner and Santiago González were the defending champions, but chose not to participate together. Demoliner played alongside Divij Sharan, but lost in the quarterfinals to Denys Molchanov and Igor Zelenay. González teamed up with Aisam-ul-Haq Qureshi, but lost in the first round to Ivan Dodig and Filip Polášek.
Austin Krajicek and Rajeev Ram were the defending champions, but chose to compete in Stockholm and Antwerp, respectively, instead.
Roman Jebavý and Andrés Molteni were the defending champions, but Jebavý chose to compete in Montpellier instead. Molteni played alongside Leonardo Mayer, but lost in the final to Marcelo Demoliner and Matwé Middelkoop, 3–6, 6–7(4–7).
Marcelo Demoliner and Matwé Middelkoop were the defending champions, but Middelkoop decide to participate in the 2021 Open Sud de France instead. Demoliner was pairing up with Santiago González, but they lost in the first round to Guillermo Durán and Andrés Molteni.
Fabiano de Paula 
