| Singles | |
|---|---|
| 2016 São Paulo Challenger de Tênis | |
| Champion |  Gonzalo Lama |
| Runner-up |  Ernesto Escobedo |
| Final score | 6–2, 6–2 |
Guido Pella was the defending champion but chose not to participate.
Gonzalo Lama won the title, defeating Ernesto Escobedo 6–2, 6–2 in the final.
André Ghem (first round) João Souza (second round) Guilherme Clezar (first round, retired) Thiago Monteiro (semifinals) Gonzalo Lama (champion)
Marcelo Arévalo (quarterfinals)
Christian Lindell (semifinals)
Maximiliano Estévez (second round, retired)| Semifinals | Final | ||||||||||||
| 5 | Gonzalo Lama | 5 | 6 | 6 | |||||||||
| 4 | Thiago Monteiro | 7 | 4 | 2 | |||||||||
| 5 | Gonzalo Lama | 6 | 6 | ||||||||||
| Ernesto Escobedo | 2 | 2 | |||||||||||
| 7 | Christian Lindell | 5 | 6 | 3 | |||||||||
| Ernesto Escobedo | 7 | 3 | 6 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | A Ghem | 1 | 6 | 5 | |||||||||||||||||||||||
| JI Londero | 6 | 2 | 7 | JI Londero | 6 | 6 | |||||||||||||||||||||
 G Escobar | 7 | 3 | 6 | G Escobar | 1 | 4 | |||||||||||||||||||||
| A Collarini | 5 | 6 | 4 | JI Londero | 6 | 66 | 5 | ||||||||||||||||||||
| Carlos Eduardo Severino | 6 | 6 | 5 | G Lama | 1 | 78 | 7 | ||||||||||||||||||||
| WC | Gabriel Décamps | 3 | 2 | CE Severino | 3 | 2 | |||||||||||||||||||||
 DE Galán | 2 | 3 | 5 | G Lama | 6 | 6 | |||||||||||||||||||||
| 5 | G Lama | 6 | 6 | 5 | G Lama | 5 | 6 | 6 | |||||||||||||||||||
| 4 | T Monteiro | 6 | 7 | 4 | T Monteiro | 7 | 4 | 2 | |||||||||||||||||||
| A Velotti | 3 | 5 | 4 | T Monteiro | 6 | 6 | |||||||||||||||||||||
| WC | Rafael Camilo | 2 | 5 | E Gómez | 4 | 3 | |||||||||||||||||||||
| E Gómez | 6 | 7 | 4 | T Monteiro | 6 | 3 | 6 | ||||||||||||||||||||
 M Bortolotti | 4 | 6 | 6 | M Bortolotti | 1 | 6 | 1 | ||||||||||||||||||||
| JC Sáez | 6 | 4 | 3 | M Bortolotti | 6 | 4 | 5 | ||||||||||||||||||||
| Juan Ignacio Galarza | 64 | 3 | 8 | M Estévez | 0 | 6 | 2r | ||||||||||||||||||||
| 8 | Maximiliano Estévez | 77 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | C Lindell | 6 | 6 | ||||||||||||||||||||||||
| Q | JP Sorgi | 1 | 2 | 7 | C Lindell | 6 | 7 | ||||||||||||||||||||
| WC | Wilson Leite | 3 | 4 | M Zormann | 3 | 5 | |||||||||||||||||||||
| M Zormann | 6 | 6 | 7 | C Lindell | 6 | 77 | |||||||||||||||||||||
| WC | FM Alves | 2 | 3 | J Pereira | 2 | 64 | |||||||||||||||||||||
| José Pereira | 6 | 6 | J Pereira | 6 | 6 | ||||||||||||||||||||||
| F Coria | 6 | 0 | F Coria | 3 | 2 | ||||||||||||||||||||||
| 3 | G Clezar | 3 | 0r | 7 | C Lindell | 5 | 6 | 3 | |||||||||||||||||||
| 6 | M Arévalo | 6 | 6 | E Escobedo | 7 | 3 | 6 | ||||||||||||||||||||
| Q | R Hocevar | 2 | 2 | 6 | M Arévalo | 77 | 77 | ||||||||||||||||||||
| C Zampieri | 78 | 61 | 6 | C Zampieri | 64 | 64 | |||||||||||||||||||||
| Q | A Miele | 66 | 77 | 2 | 6 | M Arévalo | 68 | 1 | |||||||||||||||||||
| F Mena | 3 | 1 | E Escobedo | 710 | 6 | ||||||||||||||||||||||
| E Escobedo | 6 | 6 | E Escobedo | 6 | 2 | 7 | |||||||||||||||||||||
| Q | Alexandre Tsuchiya | 2 | 0 | 2 | J Souza | 4 | 6 | 5 | |||||||||||||||||||
| 2 | J Souza | 6 | 6 | ||||||||||||||||||||||||
Facundo Bagnis was the defending champion, but lost in the semifinals to Marco Trungelliti.
This was the first edition of the tournament.
Juan Martín del Potro was the defending champion, but was unable to participate this year due to a wrist injury.
Austin Krajicek won his maiden ATP Challenger Tour singles title, beating João Souza 7–5, 6–3
Thomaz Bellucci was the defending champion, however he chose not to participate.
David Ferrer was the three-time defending champion, but he chose to compete in Acapulco instead.
Rafael Nadal won the title, defeating Juan Mónaco in the final, 6–4, 6–1.
Gonzalo Lama was the defending champion, but lost to Fernando Romboli in the quarterfinals.
Austin Krajicek was the defending champion, but chose to compete in the Japan Open instead of defending his title.
Federico Delbonis was the defending champion but chose not to participate.
Fernando Romboli was the defending champion but chose not to participate.
This was the first edition of the tournament.
This was the first edition of the tournament.
Gonzalo Lama was the defending champion but lost in the first round to João Souza.
Jonáš Forejtek was the defending champion, having won the previous edition in 2019, but was no longer eligible to participate in junior events.
Nicolás Jarry was the defending champion but chose not to defend his title.
This was the first edition of the tournament.
Antonio Veić was the defending champion but did not defend his title as he retired from professional tennis.
Wesley Koolhof and Neal Skupski defeated Ariel Behar and Gonzalo Escobar in the final, 7–6(7–5), 6–4, to win the men's doubles tennis title at the 2022 Adelaide International 2.
Marcel Granollers and Horacio Zeballos were the defending champions, when the event was last held in 2020, but lost to Jamie Murray and Bruno Soares in the semifinals.
Pedro Martínez defeated Sebastián Báez in the final, 4–6, 6–4, 6–4 to win the singles title at the 2022 Chile Open. It was his first ATP Tour title.