| Doubles | |
|---|---|
| 2021 Play In Challenger | |
| Champions |  Benjamin Bonzi Antoine Hoang |
| Runners-up | Dan Added  Michael Geerts |
| Score | 6–3, 6–1 |
Romain Arneodo and Hugo Nys were the defending champions [1] but lost in the quarterfinals to Benjamin Bonzi and Antoine Hoang.
Bonzi and Hoang won the title after defeating Dan Added and Michael Geerts 6–3, 6–1 in the final.
Sander Arends / David Pel (semifinals)
Romain Arneodo / Hugo Nys (quarterfinals)
Harri Heliövaara / 
Matt Reid (withdrew) Grégoire Barrère / Albano Olivetti (first round) Quentin Halys / Tristan Lamasine (first round)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | S Arends D Pel | 4 | 6 | [10] | |||||||||||||||||||||||
| M Bourgue A Müller | 6 | 6 | M Bourgue A Müller | 6 | 3 | [5] | |||||||||||||||||||||
 P Cachin  V Durasovic | 3 | 4 | 1 | S Arends D Pel | 1 | 3 | |||||||||||||||||||||
| 4 | G Barrère A Olivetti | 2 | 4 | D Added M Geerts | 6 | 6 | |||||||||||||||||||||
| WC | M Janvier Lilian Marmousez | 6 | 6 | WC | M Janvier L Marmousez | ||||||||||||||||||||||
| D Added M Geerts | w/o | ||||||||||||||||||||||||||
| D Added M Geerts | 3 | 1 | |||||||||||||||||||||||||
| M Martineau A Reymond | 6 | 3 | [8] | B Bonzi A Hoang | 6 | 6 | |||||||||||||||||||||
| PR |  D Brown M Guinard | 2 | 6 | [10] | PR | D Brown M Guinard | 6 | 5 | [10] | ||||||||||||||||||
 J Forejtek V Šafránek | 6 | 3 | [10] | J Forejtek V Šafránek | 1 | 7 | [7] | ||||||||||||||||||||
| 5 | Q Halys T Lamasine | 2 | 6 | [2] | PR | D Brown M Guinard | 6 | 2 | [11] | ||||||||||||||||||
| WC | Jurgen Briand Cyril Vandermeersch | 3 | 1 | B Bonzi A Hoang | 4 | 6 | [13] | ||||||||||||||||||||
| B Bonzi A Hoang | 6 | 6 | B Bonzi A Hoang | 4 | 6 | [11] | |||||||||||||||||||||
| 2 | R Arneodo H Nys | 6 | 3 | [9] | |||||||||||||||||||||||
Nikola Mektić and Antonio Šančić were the defending champions but chose not to defend their title.
Sadio Doumbia and Calvin Hemery were the defending champions but chose not to defend their title.
Nikola Mektić and Franko Škugor were the defending champions but chose not to defend their title.
Andre Begemann and Jonathan Eysseric were the defending champions but only Begemann chose to defend his title, partnering Rameez Junaid. Begemann lost in the quarterfinals to Romain Arneodo and Quentin Halys.
Hugo Nys and Tim Pütz were the defending champions but only Nys chose to defend his title, partnering Romain Arneodo. Nys successfully defended his title.
Sander Arends and Tristan-Samuel Weissborn were the defending champions but lost in the semifinals to Jonathan Eysseric and Antonio Šančić.
Bradley Klahn and Peter Polansky were the defending champions but chose not to defend their title.
Marcelo Arévalo and Miguel Ángel Reyes-Varela were the defending champions, but lost in the first round to Hans Hach Verdugo and Dennis Novikov.
Romain Arneodo and Hugo Nys were the defending champions but chose not to defend their title.
Kevin Krawietz and Andreas Mies were the defending champions but chose not to defend their title.
Luke Bambridge and Jonny O'Mara were the defending champions but only O'Mara chose to defend his title, partnering Ken Skupski. O'Mara lost in the semifinals to Hans Podlipnik Castillo and Tristan-Samuel Weissborn.
Fabrice Martin and Hugo Nys were the defending champions but chose not to defend their title.
Grégoire Barrère was the defending champion but lost in the final to Zizou Bergs.
Gerard Granollers and Pedro Martínez were the defending champions but chose not to defend their title.
Nicolas Mahut and Pierre-Hugues Herbert defeated Alexander Bublik and Andrey Golubev in the final, 4–6, 7–6(7–1), 6–4, to win the men's doubles title at the 2021 French Open. It was their second French Open title and fifth major title together. They saved match points in their semifinal match against Juan Sebastián Cabal and Robert Farah. Bublik and Golubev became the first male Kazakh players to reach a major final.
Romain Arneodo and Hugo Nys were the reigning champions from when the tournament was last held in 2019, but chose to play in Gstaad instead.
Romain Arneodo and Hugo Nys were the defending champions but only Arneodo chose to defend his title, partnering Quentin Halys. Arneodo lost in the quarterfinals to Antoine Hoang and Kyrian Jacquet.
Jonny O'Mara and Ken Skupski were the defending champions but only O'Mara chose to defend his title, partnering Treat Huey. O'Mara lost in the first round to Antoine Hoang and Kyrian Jacquet.
Hugo Nys and Jan Zieliński were the defending champions but chose not to defend their title.
Benjamin Bonzi and Antoine Hoang were the defending champions but only Hoang chose to defend his title, partnering Romain Arneodo. Hoang lost in the quarterfinals to Jonathan Eysseric and Quentin Halys.