| Singles | |
|---|---|
| 2022 Open de Rennes | |
| Champion |  Ugo Humbert |
| Runner-up |  Dominic Thiem |
| Score | 6–3, 6–0 |
Benjamin Bonzi was the defending champion [1] but chose not to defend his title.
Ugo Humbert won the title after defeating Dominic Thiem 6–3, 6–0 in the final.
Hugo Gaston (semifinals)
Peter Gojowczyk (semifinals) Hugo Grenier (second round) Ugo Humbert (champion)
Ryan Peniston (second round) Grégoire Barrère (quarterfinals) Benoît Paire (quarterfinals)
Gijs Brouwer (quarterfinals)| Semifinals | Final | ||||||||||||
| 1 | Hugo Gaston | 2 | 5 | ||||||||||
| WC | Dominic Thiem | 6 | 7 | ||||||||||
| WC | Dominic Thiem | 3 | 0 | ||||||||||
| 4 | Ugo Humbert | 6 | 6 | ||||||||||
| 4 | Ugo Humbert | 6 | 6 | ||||||||||
| 2 | Peter Gojowczyk | 3 | 4 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | H Gaston | 7 | 6 | ||||||||||||||||||||||||
| Q |  Y Mertens | 5 | 4 | 1 | H Gaston | 6 | 4 | 6 | |||||||||||||||||||
| WC | G Debru | 4 | 6 | 6 | WC | G Debru | 2 | 6 | 3 | ||||||||||||||||||
| M Rosenkranz | 6 | 3 | 4 | 1 | H Gaston | 6 | 6 | ||||||||||||||||||||
| Q | M Topo | 6 | 65 | 3 | 7 | B Paire | 3 | 1 | |||||||||||||||||||
| C Tabur | 1 | 77 | 6 | C Tabur | 3 | 3 | |||||||||||||||||||||
| D Added | 63 | 6 | 5 | 7 | B Paire | 6 | 6 | ||||||||||||||||||||
| 7 | B Paire | 77 | 4 | 7 | 1 | H Gaston | 2 | 5 | |||||||||||||||||||
| 3 | H Grenier | 6 | 6 | WC | D Thiem | 6 | 7 | ||||||||||||||||||||
| Q | Maxime Mora | 2 | 2 | 3 | H Grenier | 6 | 3 | 64 | |||||||||||||||||||
 A Andreev | 3 | 77 | 77 | A Andreev | 4 | 6 | 77 | ||||||||||||||||||||
| M Janvier | 6 | 65 | 61 | A Andreev | 6 | 3 | 2 | ||||||||||||||||||||
| WC | D Thiem | 4 | 6 | 6 | WC | D Thiem | 3 | 6 | 6 | ||||||||||||||||||
| G Simon | 6 | 3 | 2 | WC | D Thiem | 6 | 6 | ||||||||||||||||||||
| A Escoffier | 3 | 65 | 5 | R Peniston | 3 | 4 | |||||||||||||||||||||
| 5 | R Peniston | 6 | 77 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 8 | G Brouwer | 63 | 6 | 6 | |||||||||||||||||||||||
| Q | MH Rehberg | 77 | 4 | 4 | 8 | G Brouwer | 7 | 3 | 6 | ||||||||||||||||||
| WC | C Chidekh | 6 | 5 | 6 | WC | C Chidekh | 5 | 6 | 3 | ||||||||||||||||||
 G Décamps | 2 | 7 | 1 | 8 | G Brouwer | 1 | 65 | ||||||||||||||||||||
 A Bellier | 6 | 6 | 4 | U Humbert | 6 | 77 | |||||||||||||||||||||
 A Vatutin | 4 | 4 | A Bellier | 4 | 1 | ||||||||||||||||||||||
| Q |  K Friberg | 3 | 4 | 4 | U Humbert | 6 | 6 | ||||||||||||||||||||
| 4 | U Humbert | 6 | 6 | 4 | U Humbert | 6 | 6 | ||||||||||||||||||||
| 6 | G Barrère | 6 | 6 | 2 | P Gojowczyk | 3 | 4 | ||||||||||||||||||||
 H Moriya | 3 | 2 | 6 | G Barrère | 77 | 6 | |||||||||||||||||||||
| E Furness | 77 | 6 | E Furness | 62 | 4 | ||||||||||||||||||||||
| Q | F Bergevi | 63 | 2 | 6 | G Barrère | 62 | 6 | 5 | |||||||||||||||||||
| D Masur | 69 | 6 | 6 | 2 | P Gojowczyk | 77 | 4 | 7 | |||||||||||||||||||
| J De Loore | 711 | 2 | 4 | D Masur | 6 | 3 | 5 | ||||||||||||||||||||
| K de Schepper | 77 | 3 | 2 | 2 | P Gojowczyk | 2 | 6 | 7 | |||||||||||||||||||
| 2 | P Gojowczyk | 64 | 6 | 6 | |||||||||||||||||||||||
Jaume Munar was the defending champion but chose not to defend his title.
Uladzimir Ignatik was the defending champion but lost in the second round to Ugo Humbert.
Maximilian Marterer was the defending champion but chose not to defend his title.
Novak Djokovic defeated Stefanos Tsitsipas in the final, 6–3, 6–4 to win the men's singles tennis title at the 2019 Madrid Open. With the win, Djokovic tied Rafael Nadal's record of 33 Masters 1000 singles titles. He did not lose a single set in the entire tournament.
Jérémy Chardy was the defending champion but chose not to defend his title.
Damir Džumhur was the defending champion, but retired from his quarterfinal match against Jordan Thompson.
Corentin Moutet was the defending champion but chose not to defend his title.
Hubert Hurkacz was the defending champion but chose not to defend his title.
Reilly Opelka was the defending champion, but lost to Jason Jung in the quarterfinals.
Kevin Krawietz and Andreas Mies were the defending champions and successfully defended their title, defeating Mate Pavić and Bruno Soares in the final, 6–3, 7–5.
Mikael Ymer was the defending champion but chose not to defend his title.
Ugo Humbert was the defending champion but chose not to defend his title.
Carlos Alcaraz defeated the defending champion Alexander Zverev in the final, 6–3, 6–1 to win the men's singles tennis title at the 2022 Madrid Open. Alcaraz also became the first man to defeat Rafael Nadal and Novak Djokovic in the same clay court tournament, which he did in the quarterfinals and semifinals, respectively.
Altuğ Çelikbilek was the defending champion but lost in the first round to Alejandro Moro Cañas.
Benjamin Bonzi was the defending champion but chose not to defend his title.
Benjamin Bonzi was the defending champion but chose not to defend his title.
Marc-Andrea Hüsler defeated Holger Rune in the final, 6–4, 7–6(10–8) to win the singles tennis title at the 2022 Sofia Open. It was his maiden ATP Tour title, and he saved two match points en route, in his quarterfinal match against Kamil Majchrzak. Hüsler became the fourth Swiss man, after Roger Federer, Stan Wawrinka and Marc Rosset, to win an ATP Tour title in the 21st century.
Benjamin Bonzi was the defending champion but chose not to defend his title.
Ugo Humbert was the defending champion but chose not to defend his title.
Alexei Popyrin was the defending champion but chose not to defend his title.