| Singles | |
|---|---|
| 2023 Engie Open Andrézieux-Bouthéon 42 | |
| Champion |  Océane Dodin |
| Runner-up | Audrey Albié |
| Score | 3–6, 6–2, 7–5 |
Ana Bogdan was the defending champion [1] but chose not to participate.
Océane Dodin won the title, defeating Audrey Albié in the final, 3–6, 6–2, 7–5.
Océane Dodin (champion)
Ylena In-Albon (first round) Simona Waltert (quarterfinals)
Erika Andreeva (second round) Elsa Jacquemot (second round)
Daria Snigur (semifinals) Chloé Paquet (first round) Jessika Ponchet (quarterfinals)| Semifinals | Final | ||||||||||||
| 1 | Océane Dodin | 6 | 6 | ||||||||||
| 6 | Daria Snigur | 3 | 2 | ||||||||||
| 1 | Océane Dodin | 3 | 6 | 7 | |||||||||
| Audrey Albié | 6 | 2 | 5 | ||||||||||
| Oksana Selekhmeteva | 4 | 4 | |||||||||||
| Audrey Albié | 6 | 6 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | O Dodin | 6 | 6 | ||||||||||||||||||||||||
| L Nguyen Tan | 4 | 2 | 1 | O Dodin | 77 | 6 | |||||||||||||||||||||
 A Cadanțu-Ignatik | 1 | 0 | PR | S Lansere | 64 | 2 | |||||||||||||||||||||
| PR | S Lansere | 6 | 6 | 1 | O Dodin | 4 | 6 | 7 | |||||||||||||||||||
| A Robbe | 3 | 2 | 8 | J Ponchet | 6 | 1 | 5 | ||||||||||||||||||||
| Q | A Tubello | 6 | 6 | Q | A Tubello | 611 | 5 | ||||||||||||||||||||
| WC | É Dartron | 4 | 61 | 8 | J Ponchet | 713 | 7 | ||||||||||||||||||||
| 8 | J Ponchet | 6 | 77 | 1 | O Dodin | 6 | 6 | ||||||||||||||||||||
| 4 | E Andreeva | 6 | 6 | 6 | D Snigur | 3 | 2 | ||||||||||||||||||||
| Q | M Bondarenko | 0 | 0 | 4 | E Andreeva | 4 | 64 | ||||||||||||||||||||
 Z Sönmez | 6 | 5 | 6 | Z Sönmez | 6 | 77 | |||||||||||||||||||||
| I Bara | 4 | 7 | 4 | Z Sönmez | 3 | 5 | |||||||||||||||||||||
| S Bandecchi | 6 | 6 | 6 | D Snigur | 6 | 7 | |||||||||||||||||||||
| Q | C Noël | 2 | 2 | S Bandecchi | 3 | 3 | |||||||||||||||||||||
| Q | A Mitu | 5 | 6 | 5 | 6 | D Snigur | 6 | 6 | |||||||||||||||||||
| 6 | D Snigur | 7 | 4 | 7 | |||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | C Paquet | 5 | 4 | ||||||||||||||||||||||||
| O Selekhmeteva | 7 | 6 | O Selekhmeteva | 6 | 6 | ||||||||||||||||||||||
| I Shymanovich | 6 | 6 | I Shymanovich | 3 | 1 | ||||||||||||||||||||||
| Q |  A Laboutková | 3 | 4 | O Selekhmeteva | 6 | 6 | |||||||||||||||||||||
| Q | C Naef | 3 | 6 | 6 | 3 | S Waltert | 3 | 3 | |||||||||||||||||||
| A Rushiti | 6 | 3 | 4 | Q | C Naef | 6 | 3 | 4 | |||||||||||||||||||
| WC | TS Rakotomanga Rajaonah | 2 | 4 | 3 | S Waltert | 2 | 6 | 6 | |||||||||||||||||||
| 3 | S Waltert | 6 | 6 | O Selekhmeteva | 4 | 4 | |||||||||||||||||||||
| 5/WC | E Jacquemot | 6 | 7 | A Albié | 6 | 6 | |||||||||||||||||||||
 G García Pérez | 3 | 5 | 5 | E Jacquemot | 6 | 5 | 3 | ||||||||||||||||||||
| WC | G Desperrier | 4 | 3 | A Albié | 4 | 7 | 6 | ||||||||||||||||||||
| A Albié | 6 | 6 | A Albié | 6 | 6 | ||||||||||||||||||||||
| Q | A Monnot | 6 | 5 | 6 | Q | A Monnot | 1 | 3 | |||||||||||||||||||
| Q | J Belgraver | 4 | 7 | 4 | Q | A Monnot | 6 | 5 | 6 | ||||||||||||||||||
 U Radwańska | 6 | 4 | 6 | U Radwańska | 3 | 7 | 4 | ||||||||||||||||||||
| 2 | Y In-Albon | 4 | 6 | 2 | |||||||||||||||||||||||
Monica Puig was the defending champion, but lost in the first round to Samantha Stosur.
Annika Beck was the defending champion, but lost in the first round to Anna-Lena Friedsam.
Margarita Gasparyan was the defending champion, but chose not to participate.
Angelique Kerber was the defending champion and successfully defended her title, defeating Laura Siegemund in the final, 6–4, 6–0.
Karolína Plíšková was the defending champion, but lost in the semifinals to Lucie Šafářová.
Samantha Stosur was the defending champion, but withdrew before her quarterfinal match due to a left wrist injury.
Anastasia Pavlyuchenkova was the defending champion, but lost in the quarterfinals to Dominika Cibulková.
Monica Niculescu was the defending champion, but lost to Lauren Davis in the quarterfinals.
Elitsa Kostova was the defending champion from the event's previous edition as an ITF Women's Circuit tournament, but lost in the first round of qualifying to Barbora Štefková.
Ivana Jorović was the defending champion but lost in the first round to Sabina Sharipova.
Yanina Wickmayer was the defending champion, but chose not to participate this year.
Kristina Mladenovic was the defending champion, but lost in the final to unseeded Petra Kvitová, 1–6, 2–6. As a result, Kvitová became the first left-handed player to win a singles title in Russia. She was also the first wildcard to win the event.
Petra Kvitová was the defending champion, and successfully defended her title, defeating Magdaléna Rybáriková in the final, 4–6, 6–1, 6–2.
Jil Teichmann was the defending champion, but chose not to participate.
Coco Gauff was the defending champion, but chose not to participate this year.
Elina Svitolina was the defending champion but chose not to participate.
Aryna Sabalenka was the defending champion, but she chose not to compete this year.
Cristina Bucșa was the defending champion but withdrew from the tournament.
Iga Świątek defeated Anett Kontaveit in the final, 6–2, 6–0 to win the singles title at the 2022 WTA Qatar Open. This tournament marked the beginning of an eventual 37-match and six-title winning streak by Świątek.
Mihaela Buzărnescu was the defending champion but chose not to participate.