U.S. Route 11 or U.S. Highway 11 (US 11) is a major north–south United States Numbered Highway extending 1,645 miles (2,647 km) across the eastern U.S. The southern terminus of the route is at US 90 in Bayou Sauvage National Wildlife Refuge in eastern New Orleans, Louisiana. The northern terminus is at the Rouses Point–Lacolle 223 Border Crossing in Rouses Point, New York. The route continues across the border into Canada as Route 223. US 11, created in 1926, maintains most of its original route. The route north of Knoxville, Tennessee, follows a route similar to Interstate 81 (I-81). While it is signed as a north–south route, it physically travels in a northeast–southwest direction.
U.S. Route 43 (US 43) is a 410-mile-long (660 km) north–south United States Highway in the Southern states of Alabama and Tennessee. It travels from Prichard, Alabama, to Columbia, Tennessee. The highway's southern terminus is in Prichard, at an intersection with US 90, and its northern terminus is in Columbia at an intersection with US 31/US 412/US 412 Bus.
Interstate 22 (I-22) is a 202.22-mile-long (325.44 km) Interstate Highway in the US states of Mississippi and Alabama, connecting I-269 near Byhalia, Mississippi, to I-65 near Birmingham, Alabama. I-22 is also Corridor X of the Appalachian Development Highway System (ADHS). Designated in 2012, I-22 follows the route of older U.S. Route 78 (US 78) and is concurrent with the route for all but its eastern most 11 miles (18 km). The freeway mainly spans rural areas and passes numerous small towns along its route, including Fulton, Tupelo, New Albany, and Holly Springs in Mississippi and Jasper, Winfield, and Hamilton in Alabama.
Interstate 759 (I-759) is a part of the Interstate Highway System in the US state of Alabama. It is a spur route that runs for 4.54 miles (7.31 km) between the cities of Attalla and Gadsden in Etowah County. It begins at I-59 in Attalla and ends at U.S. Route 411 (US 411) in southern Gadsden adjacent to the Gadsden Mall. After it loses its I-759 designation, the route continues east as the at-grade thoroughfare State Route 759 (SR 759) until the route ends at SR 291 in Gadsden.
Interstate 359 (I-359) is a part of the Interstate Highway System in the US state of Alabama. It is a spur route that runs for 2.76 miles (4.44 km) entirely within the city limits of Tuscaloosa. Its terminuses are just south of I-20/I-59 interchange on the south side of town and U.S. Route 43 (US 43) in downtown Tuscaloosa. The entire length is concurrent with US 11 and State Route 69 (SR 69), with both continuing as at grade thoroughfares north and south of the shorter Interstate.
State Route 215 is a numbered state highway in Tuscaloosa County, Alabama. SR 215 partially follows the former routes of U.S. Route 82 and US 11. The route stays almost completely within the city limits of Tuscaloosa.
State Route 269 is a 41-mile-long (66 km) route that extends northwestward from Birmingham to Jasper. The route runs west of Interstate 22 (I-22) and roughly parallels that route. Other towns along the route include Maytown, Sylvan Springs, and Parrish.
State Route 69 is a 280-mile-long (450 km) state highway that extends from the southwestern to the northeastern parts of the U.S. state of Alabama. The southern terminus of the highway is at an intersection with SR 177 at Jackson. The northern terminus of the highway is at an intersection with US 431/SR 79 at Guntersville.
State Route 287 is a 6.370-mile-long (10.252 km) route that serves as a connection between Exit 37 off Interstate 65 (I-65) north of Bay Minette and U.S. Route 31 in downtown Bay Minette in Baldwin County.
State Route 186 is a 3.829-mile (6.162 km) state highway in Macon County. The western terminus of the route is at an interchange with Interstate 85 (I-85) approximately 9 miles (14 km) west of Auburn. The eastern terminus of the route is at its junction with US 29/US 80 approximately 8 miles (13 km) east of Tuskegee.
State Route 211 is a 4.607-mile (7.414 km) state highway that serves as a connection between Gadsden and Interstate 59 (I-59) in Reece City in central Etowah County. SR 211 intersects US 278 and US 431 at its southern terminus and US 11 at its northern terminus.
State Route 127 (SR 127) is a 13.510-mile (21.742 km) state highway that serves the north-central areas of Limestone County in the north-central part of the U.S. state of Alabama. SR 127 intersects SR 99 at its southern terminus in Athens and continues as Tennessee State Route 166 (SR 166) upon entering Tennessee at its northern terminus.
State Route 156 (SR 156) is a 7.186-mile (11.565 km) state highway that serves as a connection between Jachin and Pennington in northeastern Choctaw County. SR 156 intersects SR 17 at its western terminus and SR 114 at its eastern terminus.
State Route 188 is a 19.686-mile (31.682 km) state highway that serves as an east-west connection through southern Mobile County. SR 188 intersects Interstate 10 (I-10) at its western terminus and SR 193 at its eastern terminus.
State Route 184 is a 14.891-mile (23.965 km) state highway that serves as an east-west connection between Sheffield and SR 101. SR 184 intersects US 43/US 72 at its western terminus and SR 101 at its eastern terminus in Lawrence County.
State Route 170 is a 11.720-mile (18.862 km) state highway that serves as an east-west connection between Wetumpka and Eclectic through Elmore County. SR 170 intersects US 231 at its western terminus and SR 63 at its eastern terminus.
State Route 171 is an American 73.355-mile (118.053 km) state highway that serves as a north-south connection between Northport and Hamilton through Fayette, Marion and Tuscaloosa Counties. SR 171 intersects US 43 at its southern terminus and US 43/US 278/SR 17 at its northern terminus.
State Route 162 (SR 162) is a 14.080-mile (22.660 km) state highway in the northwestern part of Wilcox County. The western terminus of the highway is an intersection with SR 5 in Kimbrough. The eastern terminus of the highway is at an intersection with SR 28 southeast of Prairie.
State Route 605 (SR 605) is a 23.420-mile-long (37.691 km) state highway in Houston and Dale counties in the southeastern part of the U.S. state of Alabama. The southern terminus of the highway is at an intersection with U.S. Route 231 (US 231) south of Madrid. The northern terminus of the route is at another intersection with US 231 in Midland City.
SR 215 at Tuscaloosa 
I-20 / I-59 / US 11 / SR 5 at Bucksville 
