Alexandra Martha Zoya Slawin | |
---|---|
Born | 1961 (age 62–63) |
Alma mater | Loughborough University Imperial College London |
Scientific career | |
Institutions | University of St Andrews |
Thesis | The X-ray crystal structures of organic and inorganic systems (1997) |
Alexandra Martha Zoya Slawin (born 1961) is a British chemist and Professor at the University of St Andrews. Her research looks to understand the structure of supramolecular systems (e.g. rotaxanes and catenanes). She is generally considered as one of the world's leading crystallographers. She was elected Fellow of the Royal Society of Edinburgh in 2011.
Slawin studied chemistry at Imperial College London. [1] [2] After earning her bachelor's degree she worked at Imperial as an Experimental Officer on X-ray crystallography. She moved to the Loughborough University, where she completed a PhD on the crystal structures of organic and inorganic systems. [3] She demonstrated how useful single cyrstal X-ray measurements were to better understand the structures of organic and inorganic solid-state systems. [3] Toward the end of her thesis she started to focus on supramolecular chemistry, particularly macrocycles, rotaxanes and catenanes. [3]
Slawin joined the University of St Andrews in 1999. [4] She was made a professor in 2004, and serves as Director of the Molecular Structure Lab. Her lab have sophisticated fully automated instrumentation for X-Ray Diffraction, including two rotating anodes and sensitive detectors. [5] She called the system the Standard (St Andrews Automated Robotic Diffractometer), which she commercialised with Rigaku. [6]
Slawin is one of the most frequent contributors to the Cambridge Crystallographic Database, having submitted over 3,500 entries. [7] Slawin was elected Fellow of the Royal Society of Edinburgh in 2011. The Royal Society of Chemistry named her one of their Golden Authors in 2021. [8]
A polycatenane is a chemical substance that, like polymers, is chemically constituted by a large number of units. These units are made up of concatenated rings into a chain-like structure.
In macromolecular chemistry, a catenane is a mechanically interlocked molecular architecture consisting of two or more interlocked macrocycles, i.e. a molecule containing two or more intertwined rings. The interlocked rings cannot be separated without breaking the covalent bonds of the macrocycles. They are conceptually related to other mechanically interlocked molecular architectures, such as rotaxanes, molecular knots or molecular Borromean rings. Recently the terminology "mechanical bond" has been coined that describes the connection between the macrocycles of a catenane. Catenanes have been synthesised in two different ways: statistical synthesis and template-directed synthesis.
Chromium hexacarbonyl is a chromium(0) organometallic compound with the formula Cr(CO)6. It is a homoleptic complex, which means that all the ligands are identical. It is a colorless crystalline air-stable solid, with a high vapor pressure.
In chemistry, mechanically interlocked molecular architectures (MIMAs) are molecules that are connected as a consequence of their topology. This connection of molecules is analogous to keys on a keychain loop. The keys are not directly connected to the keychain loop but they cannot be separated without breaking the loop. On the molecular level, the interlocked molecules cannot be separated without the breaking of the covalent bonds that comprise the conjoined molecules; this is referred to as a mechanical bond. Examples of mechanically interlocked molecular architectures include catenanes, rotaxanes, molecular knots, and molecular Borromean rings. Work in this area was recognized with the 2016 Nobel Prize in Chemistry to Bernard L. Feringa, Jean-Pierre Sauvage, and J. Fraser Stoddart.
In chemistry, a diradical is a molecular species with two electrons occupying molecular orbitals (MOs) which are degenerate. The term "diradical" is mainly used to describe organic compounds, where most diradicals are extremely reactive and non-Kekulé molecules that are rarely isolated. Diradicals are even-electron molecules but have one fewer bond than the number permitted by the octet rule.
Dimanganese decacarbonyl, which has the chemical formula Mn2(CO)10, is a binary bimetallic carbonyl complex centered around the first row transition metal manganese. The first reported synthesis of Mn2(CO)10 was in 1954 at Linde Air Products Company and was performed by Brimm, Lynch, and Sesny. Their hypothesis about, and synthesis of, dimanganese decacarbonyl was fundamentally guided by the previously known dirhenium decacarbonyl (Re2(CO)10), the heavy atom analogue of Mn2(CO)10. Since its first synthesis, Mn2(CO)10 has been use sparingly as a reagent in the synthesis of other chemical species, but has found the most use as a simple system on which to study fundamental chemical and physical phenomena, most notably, the metal-metal bond. Dimanganese decacarbonyl is also used as a classic example to reinforce fundamental topics in organometallic chemistry like d-electron count, the 18-electron rule, oxidation state, valency, and the isolobal analogy.
John Derek Woollins is a chemist who was Provost of Khalifa University, Abu Dhabi having previously been Vice Principal, Provost of St Leonard's College, at the University of St Andrews. Woollins' reagent is named after him.
Cyclobis(paraquat-p-phenylene) belongs to the class of cyclophanes, and consists of aromatic units connected by methylene bridges. It is able to incorporate small guest molecule and has played an important role in host–guest chemistry and supramolecular chemistry.
Debbie C. Crans is a Professor of Organic, Inorganic and Biological Chemistry and of Cell and Molecular Biology at Colorado State University, where she also is a Professor Laureate of the College of Natural Sciences. Crans specializes in the fundamental chemistry and biochemistry of drugs, with particular focus on vanadium and other transition metal ions as metals in medicine and investigation of their mechanisms of toxicity.
Polyrotaxane is a type of mechanically interlocked molecule consisting of strings and rings, in which multiple rings are threaded onto a molecular axle and prevented from dethreading by two bulky end groups. As oligomeric or polymeric species of rotaxanes, polyrotaxanes are also capable of converting energy input to molecular movements because the ring motions can be controlled by external stimulus. Polyrotaxanes have attracted much attention for decades, because they can help build functional molecular machines with complicated molecular structure.
Vy Maria Dong is a Vietnamese-American Chancellor's Professor of Chemistry at the University of California, Irvine (UCI). Dong works on enantioselective catalysis and natural product synthesis. She received the Royal Society of Chemistry's Merck, Sharp & Dohme Award in 2020, the American Chemical Society's Elias James Corey Award in 2019, and the UCI's Distinguished Alumni Award in 2018.
Dorothea Fiedler is a chemical biologist and also the first female director of the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin, Germany.
Julia A. Kovacs is an American chemist specializing in bioinorganic chemistry. She is professor of chemistry at the University of Washington. Her research involves synthesizing small-molecule mimics of the active sites of metalloproteins, in order to investigate how cysteinates influence the function of non-heme iron enzymes, and the mechanism of the oxygen-evolving complex (OEC).
Guillaume De Bo is a Professor and a Royal Society University Research Fellow in the Department of Chemistry at the University of Manchester. His research is in the field of polymer mechanochemistry, where he investigates the chemistry of molecules under tension for application in synthetic chemistry, materials and mechanosensors.
Kristin Susan Bowman-James is an American chemist who is a distinguished professor at the University of Kansas. Her research makes use of host–guest chemistry to design new molecules for biology and the environment. She was awarded the 2021 American Chemical Society Award in Inorganic Chemistry.
Connie C. Lu is a Taiwanese-American inorganic chemist and a professor of chemistry at the University of Bonn. She was previously a professor of chemistry at the University of Minnesota, Twin Cities. Lu's research focuses on the synthesis of novel bimetallic coordination complexes, as well as metal-organic frameworks. These molecules and materials are investigated for the catalytic conversion of small molecules like as N2 and CO2 into value-added chemicals like ammonia and methanol. Lu is the recipient of multiple awards for her research, including the National Science Foundation CAREER Award and the Sloan Research Fellowship in 2013, and an Early Career Award from the University of Minnesota's Initiative for Renewable Energy and the Environment in 2010.
Suzanne Cathleen Bart an American chemist who is a professor of inorganic chemistry at Purdue University. Her group's research focuses on actinide organometallic chemistry, and especially the characterization of low-valent organouranium complexes, actinide complexes with redox-active ligands, and discovery of new reactions that utilize these compounds. Bart's research has applications in the development of carbon-neutral fuel sources and the remediation of polluted sites.
Hanadi Farouk Sleiman is a Canadian chemist who is Canada Research Chair in DNA Nanoscience at McGill University. Her research makes use of DNA as a template for nanomaterials. She was awarded the Natural Sciences and Engineering Research Council Polanyi Award in 2021.
Daniela A. Wilson is a Romanian scientist of organic chemistry known for her research regarding self-assembly, polymer chemistry and nanomotors. She currently holds the position of professor of systems chemistry at Radboud University Nijmegen and holds a chair at the Institute for Molecules and Materials.
Paulette Clancy is a British physicist who is Professor of Materials Science at Johns Hopkins University. Her research investigates the development of machine learning strategies to advance innovation in materials design, with a focus on complex situations.
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