Alton Ivan Sutnick (born July 6, 1928 in Trenton, New Jersey) is an American medical researcher, educator and administrator. He is the author of over 200 scholarly publications. [1]
In 1950, Alton Sutnick received his bachelor's degree in chemistry from the University of Pennsylvania and in 1954, he received his medical degree from the University of Pennsylvania School of Medicine.
In 1961 Dr. Sutnick established a laboratory for the study of pulmonary surfactant at Temple University School of Medicine. He was the first medical researcher to apply pulmonary surfactant physiological observations to adult human lung disease, including pneumonia, lung cancer and pulmonary embolism, which are all associated with atelectasis. [2] [3] [4] [5] [6] [7]
Between 1958 and 1965, Sutnick conducted research on new drug and surgical treatments for hypertension [8] [9] [10] while he was a fellow at the University of Pennsylvania School of Medicine, chief of medicine of the U.S. Army Hospital in Paris, and a faculty member at the Temple University School of Medicine. As chief of medicine at the army hospital, Sutnick observed and evaluated the first human blood marrow transplants, administered by Georges Mathé to six Yugoslav physicists who had been inadvertently exposed to lethal doses of radiation in 1959. [11] Sutnick later served as a member of the National Heart, Lung and Blood Institute's National High Blood Pressure Education Working Group.
In 1965, Sutnick joined Dr. Baruch Blumberg at The Institute for Cancer Research. Dr. Blumberg had discovered what appeared to be a persistent trait in the blood of some populations which he called "Australia antigen". Sutnick found that it was acquired and associated with inflammatory disease of the liver, drawing “the first formal connection between the mysterious antigen and hepatitis” recognizing that the antigen was likely part of a hepatitis virus. [12] Subsequent studies confirmed that it was indeed Hepatitis B virus, so Sutnick’s observation led directly to the prevention of transfusion hepatitis, the hepatitis B vaccine, and the award of the Nobel Prize to Dr. Blumberg. [13] [14] [15] [16] In 1972, Sutnick was one of the first to describe an entity that became known as hepatitis C. [17] [18]
The recognition of Hepatitis B antigen occurred in patients with Down’s Syndrome, so they became a related subject of investigation, particularly as a model for leukemia susceptibility. [19] Sutnick was the first to recognize the relationship of iron stores to cancer susceptibility, and reduced life expectancy. [20] This happened at the time when the American Oncologic Hospital became part of the Fox Chase Cancer Center. Sutnick, already Associate Director of the Institute, was appointed Director of Clinical Development for the hospital, and brought on the first full-time academic clinicians.
His susceptibility studies led him to collaborate with Dr. Daniel Miller to create Canscreen, the first cancer screening program based on risk factor analysis. [21] [22] Canscreen included not only detection, but also cancer prevention and health education, and research in cancer risk factors. In 1972 he expanded Canscreen to become the cancer control and prevention program at Fox Chase, and was asked to serve on the working group at the National Cancer Institute in planning the establishment of its National Cancer Control Program.
Sutnick was subsequently invited by the World Health Organization to help India and Indonesia develop cancer programs as well. [23] [24] [25] [26] He worked together with Soviet scientist Dr. Yuri Puchkov on the India project, the first time a Soviet-American team had addressed a health problem in another country. [27] The American Journal of Public Health recognized it as an important step of cooperation between the two rival super-powers. [28]
In 1975, Sutnick was named Dean and Professor of Medicine at The Medical College of Pennsylvania (now Drexel University College of Medicine). In 1989, he was appointed Vice President and Chief Operating Officer at the Educational Commission for Foreign Medical Graduates. Sutnick introduced a family medicine program in Moldova after the fall of the Soviet Union and also developed international programs in the United States, Israel, Spain, Ukraine and Brazil. [29] [30]
As an educator, Sutnick was a pioneer in assessing the clinical skills of medical students and residents. In the 1960s, Howard Barrows and Paula Stillman introduced the use of simulated patients so that the clinical skills of all students in a medical school class could be tested in a standardized examination. In 1989, Sutnick, collaborating with Stillman and John Norcini adapted this method so that actors in different centers could be trained to simulate the same symptoms and physical findings. This allowed the testing of large numbers of medical students and residents from around the world for U.S. certification and licensure examination purposes in multiple U.S. testing centers. They also established the validity of this clinical skills assessment by showing that the scores of students on simulated patients correlated with the subsequent ratings given by their supervisors in hospitals. [31]
He was the first to use simulated patients to demonstrate colloquial English and test the spoken English skills of graduates of foreign medical schools. [32] He introduced clinical skills examinations using simulated patients in Israel, Spain, Brazil, Russia and Ukraine, demonstrating that the examination results could be compared on the same scale across countries, languages and cultures. [33]
As the vice president of American Associates of Ben-Gurion University of the Negev, Sutnick developed partnerships for Ben Gurion with Fox Chase Cancer Center and Drexel University. [34]
Sutnick's international work has extended to over 50 nations throughout Latin America, Europe, Asia, Africa, and the Middle East. He has worked with numerous governments and universities to help them update their medical educational programs and institute higher standards of medical education and practice. For example, he helped India develop a cancer control program, worked with Indonesian officials to establish a cancer registry, and strengthened family medicine education in China, Moldova, Lithuania and Ukraine. [35] [36] [37] [38] [39] [40] These programs have improved health care services for millions of people.
Sutnick has received the following honors and awards, among others: the Torch of Learning Award from the American Friends of the Hebrew University; the Philadelphia County Medical Society’s Strittmater Gold Medal; and the American Medical Association’s Dr. William Beaumont Award in Medicine. [41] [42] [43]
A pulmonary alveolus, also known as an air sac or air space, is one of millions of hollow, distensible cup-shaped cavities in the lungs where pulmonary gas exchange takes place. Oxygen is exchanged for carbon dioxide at the blood–air barrier between the alveolar air and the pulmonary capillary. Alveoli make up the functional tissue of the mammalian lungs known as the lung parenchyma, which takes up 90 percent of the total lung volume.
A pleural effusion is accumulation of excessive fluid in the pleural space, the potential space that surrounds each lung. Under normal conditions, pleural fluid is secreted by the parietal pleural capillaries at a rate of 0.6 millilitre per kilogram weight per hour, and is cleared by lymphatic absorption leaving behind only 5–15 millilitres of fluid, which helps to maintain a functional vacuum between the parietal and visceral pleurae. Excess fluid within the pleural space can impair inspiration by upsetting the functional vacuum and hydrostatically increasing the resistance against lung expansion, resulting in a fully or partially collapsed lung.
Baruch Samuel Blumberg, known as Barry Blumberg, was an American physician, geneticist, and co-recipient of the 1976 Nobel Prize in Physiology or Medicine, for his work on the hepatitis B virus while an investigator at the NIH and at the Fox Chase Cancer Center. He was president of the American Philosophical Society from 2005 until his death.
In a physical examination, medical examination, or clinical examination, a medical practitioner examines a patient for any possible medical signs or symptoms of a medical condition. It generally consists of a series of questions about the patient's medical history followed by an examination based on the reported symptoms. Together, the medical history and the physical examination help to determine a diagnosis and devise the treatment plan. These data then become part of the medical record.
Atelectasis is the collapse or closure of a lung resulting in reduced or absent gas exchange. It is usually unilateral, affecting part or all of one lung. It is a condition where the alveoli are deflated down to little or no volume, as distinct from pulmonary consolidation, in which they are filled with liquid. It is often called a collapsed lung, although that term may also refer to pneumothorax.
Dalteparin is a low molecular weight heparin. It is marketed as Fragmin. Like other low molecular weight heparins, dalteparin is used for prophylaxis or treatment of deep vein thrombosis and pulmonary embolism to reduce the risk of a stroke or heart attack. Dalteparin acts by potentiating the activity of antithrombin III, inhibiting formation of both Factor Xa and thrombin. It is normally administered by self-injection.
Southern Illinois University School of Medicine is a medical school located in Springfield, the capital of the U.S. state of Illinois. It is part of the Southern Illinois University system, which includes a campus in Edwardsville as well as the flagship in Carbondale. The medical school was founded in 1970 and achieved full accreditation in 1972. It was founded to relieve a chronic shortage of physicians in downstate Illinois.
In health care, a simulated patient (SP), also known as a standardized patient, sample patient, or patient instructor, is an individual trained to act as a real patient in order to simulate a set of symptoms or problems. Simulated patients have been successfully utilized for education, evaluation of health care professionals, as well as basic, applied, and translational medical research.
Drexel University College of Medicine is the medical school of Drexel University, a private research university in Philadelphia, Pennsylvania. The medical school represents the consolidation of two medical schools: Hahnemann Medical College, originally founded as the nation's first college of homeopathy, and the Woman's Medical College of Pennsylvania, the first U.S. medical school for women, which became the Medical College of Pennsylvania when it admitted men in 1970; these institutions merged in 1993, became affiliated with Drexel University College of Medicine in 1998, and were fully absorbed into the university in 2002.
The University of North Carolina School of Medicine is a professional school within the University of North Carolina at Chapel Hill. It offers a Doctor of Medicine degree along with combined Doctor of Medicine / Doctor of Philosophy or Doctor of Medicine / Master of Public Health degrees.
A fellowship is the period of medical training, in the United States and Canada, that a physician, dentist, or veterinarian may undertake after completing a specialty training program (residency). During this time, the physician is known as a fellow. Fellows are capable of acting as an attending physician or a consultant physician in the specialist field in which they were trained, such as internal medicine or pediatrics. After completing a fellowship in the relevant sub-specialty, the physician is permitted to practice without direct supervision by other physicians in that sub-specialty, such as cardiology or oncology.
The United States Preventive Services Task Force (USPSTF) is "an independent panel of experts in primary care and prevention that systematically reviews the evidence of effectiveness and develops recommendations for clinical preventive services". The task force, a volunteer panel of primary care clinicians with methodology experience including epidemiology, biostatistics, health services research, decision sciences, and health economics, is funded, staffed, and appointed by the U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality.
Hepatitis B vaccine is a vaccine that prevents hepatitis B. The first dose is recommended within 24 hours of birth with either two or three more doses given after that. This includes those with poor immune function such as from HIV/AIDS and those born premature. It is also recommended that health-care workers be vaccinated. In healthy people, routine immunization results in more than 95% of people being protected.
The University of Florida College of Medicine – Jacksonville is the largest of the three University of Florida Health Science Center Jacksonville colleges — medicine, nursing and pharmacy. The college's 16 clinical science departments house more than 440 faculty members and 380 residents and fellows. The college offers 34 accredited graduate medical education programs and 10 non-standard programs.
Karen H. Antman is an American physician. She is the dean of Boston University School of Medicine and provost of the Boston University Medical Campus. Antman developed standards for the treatment of patients receiving chemotherapy including pharmacology, growth factors and mobilization of peripheral blood derived stem cells for blood and marrow transplant.
Robert Palmer Beasley was a physician, public health educator and epidemiologist whose work on hepatitis B involved extensive investigations in Taiwan. That work established that hepatitis B virus (HBV) is a primary cause of liver cancer and that hepatitis B virus is transmitted from mother to infant during childbirth. Beasley and his colleagues also proved that HBV mother-to-infant transmission is preventable by at-birth vaccination. Due to this work, the World Health Assembly designated HBV as the seventh global vaccine in 1992. He later became the author of HBV immunization policies for the World Health Organization.
Reading Hospital is a 738-bed non-profit teaching hospital located in West Reading, Pennsylvania. The hospital was established in 1867 and is the anchor institution of Tower Health.
Raman Viswanathan (1899–1982) was an Indian chest physician, medical mycologist and pulmonologist, considered by many as the father of Chest Medicine in India. He was the founder director of Vallabhbhai Patel Chest Institute, a postgraduate medical institute based in Delhi. An elected fellow of the American College of Chest Physicians, Royal College of Physicians of London, Indian National Science Academy and the Academy of Medical Sciences, United Kingdom, he was a recipient of several honors including the Forlanini Medal by Italian Tuberculosis Association and the Eugeno Morelli Prize of the National Academy of Sciences, Italy. The Government of India awarded him the third highest civilian honour of the Padma Bhushan, in 1974, for his contributions to medicine.
Sanjeev Arora, MD, MACP, FACG, an Indian American physician, is the founder and director of Project ECHO, a global tele-mentoring nonprofit dedicated to disseminating knowledge in rural and under-resourced communities.
The 2020 Nobel Prize in Physiology or Medicine was awarded to the American virologists Harvey J. Alter, Michael Houghton and Charles M. Rice "for the discovery of Hepatitis C virus." During the award ceremony on December 10, 2020, Prof. Gunilla Karlsson-Hedestam said:
"The discovery of the Hepatitis C virus by this year’s Laureates laid the foundation for our current understanding about how the virus survives in its niche during the long chronic phase of the infection, and how liver disease develops. And importantly, it led to the development of highly effective anti-viral medicines that now cure the infection in almost all treated persons."