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Amplification is a judged tendency of a person to amplify physical symptoms based on negative psychological factors such as anxiety or depression. A distinct interpretation of amplification could be sensory processing disorder involving differences in the way a person reacts to sensory input, a symptom associated autism spectrum disorder. [1] An indicidual’s psychological state has been documented to affect the course of upper respiratory tract infection, [2] [3] post-infectious irritable bowel syndrome, [4] and musculoskeletal pain. [5] Amplification is not recognized by the American Psychiatric Association.
Amplification is related to alexithymia. [6] [7] Amplification may also contribute to multiple-drug intolerance (if the adverse effects that are reported are non-specific). [8] It is unclear whether amplification is related to observations that Type A personality traits may be associated with delayed recovery after organic illness. [9] [10]
The somatosensory amplification scale (SSAS) has been validated to measure amplification. [1] The scale contains four items measured with a five-item Likert scale: