Anna L Gloyn is a geneticist, who is Professor of Pediatrics (Endocrinology) and Genetics at Stanford University. She was the recipient of the Minkowski Prize in 2014 for her research into causal mechanisms of diabetes pathogenesis. Her work has contributed to improved treatment options for people with rare forms of diabetes and helped advance our understanding of type 2 diabetes. [1] [2]
Gloyn studied for a BSc in Medical Biochemistry at the University of Surrey. [3] This was followed by a DPhil on the Molecular Genetics of Type 2 Diabetes at Green College at the University of Oxford, supervised by Professor Robert Turner. She worked at the University of Exeter for her post-doctoral training, supervised by Professors Andrew Hattersley & Sian Ellard, as well as Professor Franz M. Matschinsky at the University of Pennsylvania. [4]
In 2004 Gloyn returned to the University of Oxford funded by a Diabetes UK RD Lawrence Career Development Fellowship to establish a research group to examine "beta-cell function through the investigation of genetic variants causally implicated in monogenic diabetes". [5] In 2011 she was awarded a Wellcome Senior Fellowship in Basic Biomedical Science to continue her research. This was renewed in 2016. [5] Her research has focused on how human genetic variants can be used as tools to examine how insulin secretion and action are regulated. [6] In 2014 she was awarded the Minkowski Prize. [7] The same year she was promoted to Professor of Molecular Genetics & Metabolism. [8]
In 2020 Gloyn was appointed Professor of Pediatrics (Endocrinology) and, by courtesy, of Genetics, at Stanford University. [5] This appointment enabled the movement of her research group to Stanford where it now runs as the Translational Genomics of Diabetes Lab. [9]
Gloyn is a founding member of the International Common Disease Alliance (ICDA). [10] She is also a member of the executive committee of the Atlas of Variant Effects Alliance. [11]
Oskar Minkowski was a German physician and physiologist who held a professorship at the University of Breslau and is most famous for his research on diabetes. He was the brother of the mathematician Hermann Minkowski and father of astrophysicist Rudolph Minkowski.
The Minkowski Prize is given by the European Association for the Study of Diabetes (EASD) in recognition to research which has been carried out by a person normally residing in Europe, as manifested by publications which contribute to the advancement of knowledge concerning diabetes mellitus. The Prize honors the name of Oskar Minkowski (1858–1931), a physician and physiologist who was the discoverer of the role of pancreas in the control of glucose metabolism. It has been awarded annually since 1966, and the winner is invited to pronounce a Minkowski Lecture during the EASD Annual Conference. It is traditionally seen as the most prestigious European prize in the field of diabetes research.
Green Templeton College (GTC) is a constituent college of the University of Oxford in the United Kingdom. The college is located on the former Green College site on Woodstock Road next to the Radcliffe Observatory Quarter in North Oxford and is centred on the architecturally important Radcliffe Observatory, an 18th-century building, modelled on the ancient Tower of the Winds at Athens. It is the university's second newest graduate college, after Reuben College, having been founded by the historic merger of Green College and Templeton College in 2008.
The European Association for the Study of Diabetes (EASD) is a scientific association founded in Montecatini Terme, Italy in 1965 with Joseph Hoet as Founding President. The aims of the association are to encourage and support research in the field of diabetes, the rapid diffusion of acquired knowledge in that field, and to facilitate its application.
Gilean Alistair Tristram McVean is a professor of statistical genetics at the University of Oxford, fellow of Linacre College, Oxford and co-founder and director of Genomics plc. He also co-chaired the 1000 Genomes Project analysis group.
Alastair Buchan is a British neurologist and researcher in stroke medicine. His main research interest is how to make neuroprotection a reality in the clinic. From October 2008 until January 2017, he served as the Dean of Medicine and the Head of the Medical Sciences Division, University of Oxford. He currently holds the Chair of Stroke Research at the University of Oxford.
John Andrew Todd FMedSci FRS is Professor of Precision Medicine at the University of Oxford, director of the Wellcome Center for Human Genetics and the JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, in addition to Jeffrey Cheah Fellow in Medicine at Brasenose College. He works in collaboration with David Clayton and Linda Wicker to examine the molecular basis of type 1 diabetes.
Aviv Regev is a computational biologist and systems biologist and Executive Vice President and Head of Genentech Research and Early Development in Genentech/Roche. She is a core member at the Broad Institute of MIT and Harvard and professor at the Department of Biology of the Massachusetts Institute of Technology. Regev is a pioneer of single cell genomics and of computational and systems biology of gene regulatory circuits. She founded and leads the Human Cell Atlas project, together with Sarah Teichmann.
The Wellcome Centre for Human Genetics is a human genetics research centre of the Nuffield Department of Medicine in the Medical Sciences Division, University of Oxford, funded by the Wellcome Trust among others.
The various academic faculties, departments, and institutes of the University of Oxford are organised into four divisions, each with its own Head and elected board. They are the Humanities Division; the Social Sciences Division; the Mathematical, Physical and Life Sciences Division; and the Medical Sciences Division.
David Benjamin Goldstein is an American human geneticist. Goldstein is founding Director of the Institute for Genomic Medicine at the Columbia University Medical Center, Professor of Genetics and Development and directs the genomics core of Epi4K and administrative cores of Epi4K with Dan Lowenstein and Sam Berkovic.
Eleftheria Zeggini is a director of the institute of translational genomics in Helmholtz Zentrum München and a professor at the Technical University of Munich (TUM). Previously she served as a research group leader at the Wellcome Trust Sanger Institute from 2008 to 2018 and an honorary professor in the department of health sciences at the University of Leicester in the UK.
Andrew Tym Hattersley CBE FRS is a Professor of Molecular Medicine at the University of Exeter and is known for his research in monogenic diabetes. He was elected a Fellow of the Royal Society in 2010. He is also an Emeritus Senior Investigator at the National Institute for Health and Care Research (NIHR).
Nicole Soranzo is an Italian-British senior group leader in human genetics at the Wellcome Sanger Institute, Professor of Human Genetics at the University of Cambridge. She is an internationally recognised Human Geneticist who has focused on the application of cutting edge genomic technologies to study the spectrum of human genetic variation associated with cardio-metabolic and immune diseases. She has led many large-scale discovery efforts including more than 1,000 novel genetic variants associated with cardio-metabolic diseases and their risk factors as well as establishing the HaemGen consortium, which is a worldwide effort to discover genetic determinants of blood cell formation and also interpretation of the downstream consequences of sequence variation through a host of integrative analyses and functional approaches.
Miriam Cnop is a Belgian researcher and physician specializing in diabetology. She is Professor of Medicine at Université Libre de Bruxelles and Clinical Director of Erasmus Hospital’s Endocrinology Department. Her work centered on type 2 diabetes, in particular mechanisms of lipotoxicity using human islets of Langerhans and human induced pluripotent stem cell-derived β Cells. She is an associate member of the Royal Academy of Medicine of Belgium. In 2013, her work was awarded the Oskar Minkowski prize from the European Association for the Study of Diabetes.
Tao Dong is a Chinese-British immunologist who is Professor of Immunology at Oxford University. Her work focuses on the study of T-cells which respond to viral infections and viral associated cancer. She is a founding director for both the CAMS-Oxford joint International Center for Transnational Immunology and the Chinese Academy of Medical Sciences Oxford Institute (COI).
Cecilia Margareta Lindgren is a Swedish geneticist. She is a Professor of Genomic Endocrinology & Metabolism in the Nuffield Department of Population Health at the University of Oxford, where she is also Group Head at the Wellcome Centre for Human Genetics and a research fellow at St. Anne's College. She became Director of the Big Data Institute at Oxford on 1 April 2021; she had previously been a Senior Group Leader at the Institute. Lindgren is best known for her research on the genetics of obesity and other complex traits.
Hannele Yki-Järvinen is a Finnish endocrinologist, who specialises in non-alcoholic fatty liver disease (NAFLD) and the treatment of type 2 diabetes.
Jenny Carmeron Taylor is a British geneticist who is Professor of Translational Genomics at the University of Oxford. Taylor is the Director of the Oxford Biomedical Research Centre Genetics Theme. Her research considers whole genome sequencing and ways to integrate genetic research into the National Health Service.
Anne Goriely is a British geneticist who is a professor of human genetics at the University of Oxford. Her research investigates the molecular mechanisms that underpin genetic variation, particularly mutations in the male germline.
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