Asperger syndrome (AS), also known as Asperger's, was the name of a neurodevelopmental disorder no longer recognised as a diagnosis in itself, having been merged into autism spectrum disorder (ASD). It was characterized by significant difficulties in social interaction and nonverbal communication, along with restricted and repetitive patterns of behaviour and interests. It was said to differ from other diagnoses that were merged into ASD by relatively unimpaired language and intelligence. The syndrome was named after the Austrian pediatrician Hans Asperger, who, in 1944, described children in his care who struggled to form friendships, did not understand others' gestures or feelings, engaged in one-sided conversations about their favourite interests, and were clumsy.
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. Chelation therapy has a long history of use in clinical toxicology and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of mercury and other metals through the brain and other parts of the body by the use of weak chelating agents that unbind with metals before elimination, exacerbating existing damage. To avoid mobilization, some practitioners of chelation use strong chelators, such as selenium, taken at low doses over a long period of time.
Bernard Rimland was an American research psychologist, writer, lecturer, and influential person in the field of developmental disorders. Rimland's first book, Infantile Autism, sparked by the birth of a son who had autism, was instrumental in changing attitudes toward the disorder. Rimland founded and directed two advocacy groups: the Autism Society of America (ASA) and the Autism Research Institute. He promoted several since disproven theories about the causes and treatment of autism, including vaccine denial, facilitated communication, chelation therapy, and false claims of a link between secretin and autism. He also supported the ethically controversial practice of using aversives on autistic children.
High-functioning autism (HFA) is an autism classification where a person exhibits no intellectual disability, but may exhibit deficits in communication, emotion recognition and expression, and social interaction. HFA is not included in either the American Psychological Association's DSM-5 or the World Health Organization's ICD-10, neither of which subdivides autism based on intellectual capabilities.
Generation Rescue is a nonprofit organization that advocates the scientifically disproven view that autism and related disorders are primarily caused by environmental factors, particularly vaccines. The organization was established in 2005 by Lisa and J.B. Handley. Today, Generation Rescue is known as a platform for Jenny McCarthy's autism related anti-vaccine advocacy.
The following outline is provided as an overview of and topical guide to autism:
The Autism Society of America (ASA) was founded in 1965 by Bernard Rimland and Ivar Lovaas together with Ruth C. Sullivan and a small group of other parents of children with autism. Its original name was the National Society for Autistic Children; the name was changed to emphasize that children with autism grow up. The ASA's stated goal is to increase public awareness about autism and the day-to-day issues faced by autistic people as well as their families and the professionals with whom they interact. Although the group has promoted the pseudoscientific belief that vaccines cause autism in the past, it now affirms that there is no link between vaccination and autism. In 2021, the ASA launched a new brand including a logo consisting of multicolor lines forming a fabric with a new slogan, "The Connection Is You".
Autism therapies include a wide variety of therapies that claim to help people with autism, or their families. Such methods of therapy also seek the increase of functional independence in autistic people. Many therapies marketed towards autistic people and/or their parents claim outcomes that have not been supported by Level of Research (LOE) Level 1 Level 1 research includes evidence from a systematic review or meta-analysis of all relevant RCTs or evidence-based clinical practice guidelines based on systematic reviews of RCTs or three or more RCTs of good quality that have similar results.
Derrick Lonsdale is an American pediatrician and researcher into the benefits of certain nutrients in preventing disease and psychotic behavior. He is a Fellow of the American College of Nutrition (FACN), and also a Fellow of the American College for Advancement in Medicine (FACAM)
Alternative therapies for developmental and learning disabilities include a range of practices used in the treatment of dyslexia, ADHD, autism spectrum disorders, Down syndrome and other developmental and learning disabilities. Treatments include changes in diet, dietary supplements, biofeedback, chelation therapy, homeopathy, massage and yoga. These therapies generally rely on theories that have little scientific basis, lacking well-controlled, large, randomized trials to demonstrate safety and efficacy; small trials that have reported beneficial effects can be generally explained by the ordinary waxing and waning of the underlying conditions.
Kanner autism, or classic autism, is an outdated neurodevelopmental diagnosis which is now considered part of autism spectrum disorder. The term 'autism' was historically used to refer specifically to classic autism, but it is now more commonly used for the spectrum at large.
The autism spectrum is a range of neurodevelopmental conditions generally characterized by difficulties in social interactions and communication, repetitive behaviors, intense interests, and unusual responses to sensory stimuli. It is commonly referred to as autism or, in the context of a professional diagnosis, autism spectrum disorder (ASD), but the latter term remains controversial among neurodiversity advocates, neurodiversity researchers, and many autistic people due to the use of the word disorder and due to questions about its utility outside of diagnostic contexts.
Jeffrey A. Brent is a medical toxicologist who is a distinguished clinical professor of medicine and emergency medicine at the University of Colorado, School of Medicine. In addition, he is a professor at the Department of Environmental and Occupational Health at the Colorado School of Public Health. He is also the past president of the American Academy of Clinical Toxicology, was editor in chief of the journal Toxicological Reviews, and was a member of the board of directors of the American College of Medical Toxicology. Previously, most of Brent's research focused on the use of fomepizole as a treatment for both methanol and ethylene glycol poisoning, and he led a trial of this drug which resulted in the FDA approving it in December 1997. Currently, Brent serves as Director of the Toxicology Investigators Consortium, an NIH and FDA supported multi center research and surveillance group. Brent is also a senior editor of "Critical Care Toxicology: Diagnosis and Management of the Critically Poisoned Patient," originally published in 2005, and now in its second edition, which was published in 2017.
James Jeffrey "Jeff" Bradstreet, was an American doctor, alternative medicine practitioner, and a former preacher who ran the International Child Development Resource Center in Melbourne, Florida, a medical practice in Buford, Georgia and in Arizona, where he practiced homeopathy. He also founded the Good News Doctor Foundation, which aimed to combine Christian beliefs with his medical practice.
Daniel A. Rossignol, MD, FAAFP, is a family medicine doctor. Rossignol runs the Rossignol Medical Center, with offices in Melbourne, Florida and in Aliso Viejo, California. He also works at the Wisconsin Integrative Hyperbaric Center in Fitchburg, Wisconsin, and is a member of the physician advisory board for The Autism Community in Action. Rossignol is known for his advocacy of certain autism therapies.
James B. Adams is a President's Professor at Arizona State University, where he directs the autism/Asperger's research program, though he originally taught chemical and materials engineering there. Adams also holds a post at the Southwest College of Naturopathic Medicine. He is also the president of the Autism Society of Greater Phoenix, the co-chair of the Autism Research Institute's scientific advisory committee, and has received the Autism Service Award from the Greater Phoenix chapter of the Autism Society of America. He has been featured on Dateline NBC, and received a National Science Foundation Presidential Young Investigator Award from President George Bush in 1996.
Karoly Horvath is a Hungarian-American pediatrician and gastroenterologist who was formerly the director of the Pediatric Gastroenterology and Nutrition Laboratory at the University of Maryland School of Medicine. He is best known for proposing a link between secretin, gastrointestinal disorders and autism and for, as a result, proposing that secretin might be an effective treatment for autism.
Low-functioning autism (LFA) is a degree of autism marked by difficulties with social communication and interaction, challenging behavior, and differences in social or emotional reciprocity. Sleep problems, aggression, stereotypical, and self-injurious behavior are also common symptoms. LFA is not a recognized diagnosis in the DSM-5 or ICD-10, as neither subdivides autism based on intellectual capabilities.
CEASE therapy is a pseudoscientific practice used by naturopaths who claim that it can treat or even cure people with autism, claims which have been adjudicated by the UK's Advertising Standards Authority as "bogus". It involves a mixture of supplements, high-dose vitamin C, 'orthomolecular support', dietary restrictions, and homeopathy. The therapy was developed by Dutch doctor Tinus Smits, who claimed to have used it to treat over 300 children with autism. It became more notable in 2017/2018 because of regulatory action taken by professional bodies in The Netherlands, UK, and Canada following a series of complaints about unfounded claims.
