Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. Infection of other organs can cause a wide range of symptoms.
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection.
Encephalitis is inflammation of the brain. The severity can be variable with symptoms including reduction or alteration in consciousness, headache, fever, confusion, a stiff neck, and vomiting. Complications may include seizures, hallucinations, trouble speaking, memory problems, and problems with hearing.
Herd immunity is a form of indirect protection that applies only to contagious diseases. It occurs when a sufficient percentage of a population has become immune to an infection, whether through previous infections or vaccination, thereby reducing the likelihood of infection for individuals who lack immunity.
Whooping cough, also known as pertussis or the 100-day cough, is a highly contagious, vaccine-preventable bacterial disease. Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or three months of severe coughing fits. Following a fit of coughing, a high-pitched whoop sound or gasp may occur as the person breathes in. The violent coughing may last for 10 or more weeks, hence the phrase "100-day cough". The cough may be so hard that it causes vomiting, rib fractures, and fatigue. Children less than one year old may have little or no cough and instead have periods where they cannot breathe. The incubation period is usually seven to ten days. Disease may occur in those who have been vaccinated, but symptoms are typically milder.
Varicella zoster virus (VZV), also known as human herpesvirus 3 or Human alphaherpesvirus 3 (taxonomically), is one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young adults, and shingles in adults but rarely in children. As a late complication of VZV infection, Ramsay Hunt syndrome type 2 may develop in rare cases. VZV infections are species-specific to humans. The virus can survive in external environments for a few hours.
The American Society for Microbiology (ASM), originally the Society of American Bacteriologists, is a professional organization for scientists who study viruses, bacteria, fungi, algae, and protozoa as well as other aspects of microbiology. It was founded in 1899. The Society publishes a variety of scientific journals, textbooks, and other educational materials related to microbiology and infectious diseases. ASM organizes annual meetings, as well as workshops and professional development opportunities for its members.
Mycoplasmataceae is a family of bacteria in the order Mycoplasmatales. This family consists of the genera Mycoplasma and Ureaplasma.
Medical microbiology, the large subset of microbiology that is applied to medicine, is a branch of medical science concerned with the prevention, diagnosis and treatment of infectious diseases. In addition, this field of science studies various clinical applications of microbes for the improvement of health. There are four kinds of microorganisms that cause infectious disease: bacteria, fungi, parasites and viruses, and one type of infectious protein called prion.
Anita Rachlis, M.D. is a Canadian HIV/AIDS researcher and is the principal author of the HIV treatment guidelines in Canada. She is an associate scientist at the Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, in Toronto, Ontario, Canada.
Allan R. Ronald is a Canadian doctor and microbiologist. He has been instrumental in the investigation into sexually transmitted infections in Africa, particularly in the fields of HIV/AIDS. Ronald is the recipient of multiple awards and honours.
Clostridioides difficile is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. It is known also as C. difficile, or C. diff, and is a Gram-positive species of spore-forming bacteria. Clostridioides spp. are anaerobic, motile bacteria, ubiquitous in nature and especially prevalent in soil. Its vegetative cells are rod-shaped, pleomorphic, and occur in pairs or short chains. Under the microscope, they appear as long, irregular cells with a bulge at their terminal ends. Under Gram staining, C. difficile cells are Gram-positive and show optimum growth on blood agar at human body temperatures in the absence of oxygen. C. difficile is catalase- and superoxide dismutase-negative, and produces up to three types of toxins: enterotoxin A, cytotoxin B and Clostridioides difficile transferase. Under stress conditions, the bacteria produce spores that are able to tolerate extreme conditions that the active bacteria cannot tolerate.
Elizabeth Osborne King was an American microbiologist who discovered and described bacteria of medical importance at the United States Centers for Disease Control and Prevention from the late 1940s through the early 1960s. A 1984 CDC manual dedication referred to King as "internationally known as an authority on a variety of unusual bacteria." The genera Kingella and Elizabethkingia and several species of bacteria are named to honor her for her pioneering work. King died of cancer on April 8, 1966, in Atlanta, where she is interred in Oakland Cemetery.
The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) is a non-profit international organization with headquarters in Basel, Switzerland. An important activity of the society is the organization of the annual scientific congress ESCMID Global.
Samir Kumar Saha is an eminent Bangladeshi microbiologist and public health expert. He is the professor, senior consultant and head of the department of Diagnostic Division of Microbiology at the Dhaka Shishu Hospital for children and also the executive director of The Child Health Research Foundation (CHRF) at the Bangladesh Institute of Child Health.
Allison Joan McGeer is a Canadian infectious disease specialist in the Sinai Health System, and a professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto. She also appointed at the Dalla Lana School of Public Health and a Senior Clinician Scientist at the Lunenfeld-Tanenbaum Research Institute, and is a partner of the National Collaborating Centre for Infectious Diseases. McGeer has led investigations into the severe acute respiratory syndrome outbreak in Toronto and worked alongside Donald Low. During the COVID-19 pandemic, McGeer has studied how SARS-CoV-2 survives in the air and has served on several provincial committees advising aspects of the Government of Ontario's pandemic response.
Robin Patel is a Canadian born microbiologist and Elizabeth P. and Robert E. Allen Professor of Individualized Medicine, a Professor of Microbiology, and a Professor of Medicine at the Mayo Clinic. She is widely recognized as a leader in the field of clinical microbiology and has held a variety of leadership positions including 2019–2020 President of the American Society for Microbiology (ASM) and Director of the Antibacterial Resistance Leadership Group (ARLG) Laboratory Center of the National institutes of Health. She is currently the Vice Chair of Education in the Department of Laboratory Medicine and Pathology at the Mayo Clinic, and Director of the Mayo Clinic's Infectious Diseases Research Laboratory, where she studies biofilms, antimicrobial resistance, periprosthetic joint infection and diagnostic testing of bacteria.
Caroline Quach-Thanh is a Canadian pediatric microbiologist, epidemiologist and infectious diseases specialist. She is a professor in the Université de Montréal Faculty of Medicine and Medical Lead in the Infection Prevention and Control Unit at CHU Sainte-Justine. She served as the Chair of the National Advisory Committee on Immunization (NACI) before and during the COVID-19 pandemic, and oversaw the approval process of COVID-19 vaccines in Canada.
Albert Balows was an American clinical microbiologist. He was the president of the American Society for Microbiology in 1981.
Janet Gilsdorf is an American pediatric infectious diseases physician, scientist, and writer at the University of Michigan. Her research has focused on the pathogenic, molecular, and epidemiologic features of the bacterium Haemophilus influenzae. She served as the Director of the Division of Pediatric Infectious Diseases in the University of Michigan Health System from 1989 to 2012 and Co-Director of the Center for Molecular and Clinical Epidemiology of Infectious Diseases at the School of Public Health at the University of Michigan from 2000 – 2015. In addition to her scientific publications, she is also the author of two novels, one memoir, one non-fiction book, and a number of medically-oriented essays.
