Atanu Kumar Pati is an Indian zoologist, served as the Vice-Chancellor Gangadhar Meher University (GMU), Sambalpur, Odisha from 2017 till 2020. [1]
Pati did his B.Sc. from Utkal University and M.Sc. (1977) and Ph.D. (1982) in Zoology from Banaras Hindu University. He has also received the UGC Research Award in 2002. He has also been elected as Fellow of the National Academy of Sciences, India (FNASc) in 2003. He presided the Indian Society for Chronobiology as its president from 2008 till 2017. He served the International Society of Subterranean Biology [Société Internationale de Biospéologie] as its Council Member, from 2004 to 2010. He is also Professor, Head, Dean, School of Life Sciences Pandit Ravishankar Shukla University (on lien).
BSc (1975) - Utkal University; MSc (1977) - Banaras Hindu University; PhD (1982) - Banaras Hindu University; Cours de Chronobiologie (1986) - L’Université V, Paris. Post-doctoral research at Hôpital Paul Brousse, Villejuif (L’Université V, Paris). Faculty — School of Life Sciences - (1983- Present). Council Member, World Federation of Societies of Chronobiology, 2002–2006. Recipient of UGC Research Award, 2002. Fellow of the National Academy of Sciences (FNASc), India, 2003. Council Member, International Society of Subterranean Biology, 2004–2010. Member, International Scientific Board, 1st, 2nd, 3rd International Congress of Applied Chronobiology and Chronomedicine. Editor-in-Chief, Newsletter, Indian Society for Chronobiology, 1995–1997, 2000–2009. Editor-in-Chief, Journal of Ravishankar University, Part B (Science) from 2009–present. President, Indian Society for Chronobiology, from 2009–present.
The main focus of his research involves study of circadian clocks in shift workers, cancer patients and cave fish. In addition, he studies cognitive abilities, with reference to short-interval judgment, in human subjects. He also studied cognitive abilities involving case construction behavior in a species of bagworm moth. He demonstrated alteration in temporal organization in human subjects, who carry out rotational shift duties. He reported disruption of circadian rhythm in cognitive judgment of short-time intervals in shift workers. He proposed a model for optimization of human shift work. He reported that shift work might reduce human longevity. He reported disruption of circadian clock in cancer patients and suggested implementation of patient-specific chronotherapeutic protocol. He demonstrated functional circadian oscillators in cave fish and reinterpreted findings of others to rule out the hypothesis of clock regression in hypogean fish. He reported rhythmic pattern in case architecture of bagworm moth. He proposed a model illustrating the ability of this moth to process thorn length and distance signals hierarchically during case construction through toggling its preference between thorns and cut-twigs.
A circadian rhythm, or circadian cycle, is a natural oscillation that repeats roughly every 24 hours. Circadian rhythms can refer to any process that originates within an organism and responds to the environment. Circadian rhythms are regulated by a circadian clock whose primary function is to rhythmically co-ordinate biological processes so they occur at the correct time to maximize the fitness of an individual. Circadian rhythms have been widely observed in animals, plants, fungi and cyanobacteria and there is evidence that they evolved independently in each of these kingdoms of life.
Advanced Sleep Phase Disorder (ASPD), also known as the advanced sleep-phase type (ASPT) of circadian rhythm sleep disorder, is a condition that is characterized by a recurrent pattern of early evening sleepiness and very early morning awakening. This sleep phase advancement can interfere with daily social and work schedules, and results in shortened sleep duration and excessive daytime sleepiness. The timing of sleep and melatonin levels are regulated by the body's central circadian clock, which is located in the suprachiasmatic nucleus in the hypothalamus.
Light therapy, also called phototherapy or bright light therapy is the exposure to direct sunlight or artificial light at controlled wavelengths in order to treat a variety of medical disorders, including seasonal affective disorder (SAD), circadian rhythm sleep-wake disorders, cancers, and skin wound infections. Treating skin conditions such as neurodermatitis, psoriasis, acne vulgaris, and eczema with ultraviolet light is called ultraviolet light therapy.
Shift work is an employment practice designed to keep a service or production line operational at all times. The practice typically sees the day divided into shifts, set periods of time during which different groups of workers perform their duties. The term "shift work" includes both long-term night shifts and work schedules in which employees change or rotate shifts.
A zeitgeber is any external or environmental cue that entrains or synchronizes an organism's biological rhythms, usually naturally occurring and serving to entrain to the Earth's 24-hour light/dark and 12-month cycles.
Melatonin receptors are G protein-coupled receptors (GPCR) which bind melatonin. Three types of melatonin receptors have been cloned. The MT1 (or Mel1A or MTNR1A) and MT2 (or Mel1B or MTNR1B) receptor subtypes are present in humans and other mammals, while an additional melatonin receptor subtype MT3 (or Mel1C or MTNR1C) has been identified in amphibia and birds. The receptors are crucial in the signal cascade of melatonin. In the field of chronobiology, melatonin has been found to be a key player in the synchrony of biological clocks. Melatonin secretion by the pineal gland has circadian rhythmicity regulated by the suprachiasmatic nucleus (SCN) found in the brain. The SCN functions as the timing regulator for melatonin; melatonin then follows a feedback loop to decrease SCN neuronal firing. The receptors MT1 and MT2 control this process. Melatonin receptors are found throughout the body in places such as the brain, the retina of the eye, the cardiovascular system, the liver and gallbladder, the colon, the skin, the kidneys, and many others. In 2019, X-ray crystal and cryo-EM structures of MT1 and MT2 were reported.
Ignacio Provencio is an American neuroscientist and the discoverer of melanopsin, an opsin found in specialized photosensitive ganglion cells of the mammalian retina. Provencio served as the program committee chair of the Society for Research on Biological Rhythms from 2008 to 2010.
Cavefish or cave fish is a generic term for fresh and brackish water fish adapted to life in caves and other underground habitats. Related terms are subterranean fish, troglomorphic fish, troglobitic fish, stygobitic fish, phreatic fish, and hypogean fish.
Serge Daan was a Dutch scientist, known for his significant contributions to the field of Chronobiology.
Charles Andrew Czeisler is a Hungarian-American physician and sleep and circadian researcher. He is a leading researcher and author in the fields of the effects of light on human physiology, circadian rhythms and sleep medicine.
Colin Stephenson Pittendrigh was a British-born biologist who spent most of his adult life in the United States. Pittendrigh is regarded as the "father of the biological clock," and founded the modern field of chronobiology alongside Jürgen Aschoff and Erwin Bünning. He is known for his careful descriptions of the properties of the circadian clock in Drosophila and other species, and providing the first formal models of how circadian rhythms entrain (synchronize) to local light-dark cycles.
Eleanor Beatrice Marcy "Beazy" Sweeney was an American plant physiologist and a pioneering investigator into circadian rhythms. At the time of her death she was professor emerita at the University of California, Santa Barbara, where she had worked since 1961.
Ueli Schibler is a Swiss biologist, chronobiologist and a professor at the University of Geneva. His research has contributed significantly to the field of chronobiology and the understanding of circadian clocks in the body. Several of his studies have demonstrated strong evidence for the existence of robust, self-sustaining circadian clocks in the peripheral tissues.
In chronobiology, the circannual cycle is characterized by biological processes and behaviors recurring on an approximate annual basis, spanning a period of about one year. This term is particularly relevant in the analysis of seasonal environmental changes and their influence on the physiology, behavior, and life cycles of organisms. Adaptations observed in response to these circannual rhythms include fur color transformation, molting, migration, breeding, fattening and hibernation, all of which are inherently driven and synchronized with external environmental changes.
Achim Kramer is a German chronobiologist and biochemist. He is the current head of Chronobiology at Charité – Universitätsmedizin Berlin in Berlin, Germany.
Nicholas Mrosovsky was a Canadian zoologist known for his research in the fields of homeostasis, chronobiology, and sea turtle biology. He spent his whole professional career at the University of Toronto. His laboratory was notable for its seminal investigations of the influence of behavioural arousal on circadian rhythms. He was also the founder, in 1976, of Marine Turtle Newsletter. He received a Guggenheim Fellowship in 1973, and in 1993 he was elected a Fellow of the Royal Society of Canada.
Anil Kumar Gupta is a scientist and researcher from India who served as a professor in the Department of Geology and Geophysics at the Indian Institute of Technology Kharagpur. He was also the former director (2010–2017) of the Wadia Institute of Himalayan Geology, Dehradun, India. His teaching interests include applied micropaleontology, paleoceanography and marine geosciences.
In chronobiology, photoentrainment refers to the process by which an organism's biological clock, or circadian rhythm, synchronizes to daily cycles of light and dark in the environment. The mechanisms of photoentrainment differ from organism to organism. Photoentrainment plays a major role in maintaining proper timing of physiological processes and coordinating behavior within the natural environment. Studying organisms’ different photoentrainment mechanisms sheds light on how organisms may adapt to anthropogenic changes to the environment.
Martin R. Ralph is a circadian biologist who serves as a professor in the Psychology Department at the University of Toronto. His research primarily focuses on circadian rhythmicity in the fields of neuroscience, psychology, and endocrinology. His most notable work has been on the suprachiasmatic nucleus, now recognized as the central circadian pacemaker in mammals, but has also investigated circadian rhythms in the context of time, memory, and light.
Chronodisruption is a concept in the field of circadian biology that refers to the disturbance or alteration of the body's natural biological rhythms, for example the sleep-wake cycle, due to various environmental factors. The human body is synchronized to a 24-hour light-dark cycle, which is essential for maintaining optimal health and well-being. However, modern lifestyles —which involve exposure to artificial light, irregular sleep schedules, and shift work — can disrupt this natural rhythm, leading to a range of adverse physiological outcomes. Chronodisruption has been linked to a variety of health disorders and diseases, including neurodegenerative diseases, diabetes, mood disorders, cardiovascular disease, and cancer. Such disruptors can lead to dysregulation of hormones and neurotransmitters, though researchers continue to investigate the physiological implications of chronodisruption. Indeed, research in chronobiology is rapidly advancing, with an increasing focus on understanding the underlying mechanisms of chronodisruption and developing strategies to prevent or mitigate its adverse effects. This includes the development of pharmacological interventions, as well as lifestyle modifications such as optimizing one's sleeping environment and timing of meals and physical activity.