Baljet reaction

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The Baljet reaction is a qualitative and quantitative method of analysis published by Henri Baljet [1] in 1918. [2] This chemical reaction is used for the detection and colorimetric [3] determination of cardenolides. To the sample, an aqueous hydroxide solution and an ethanolic picric acid solution is combined and added, with a positive test turning orange or red. [4] [5] [ better source needed ] The mechanism involves cardenolides 1 reacting in alkaline solution with picric acid 2 to form stabilized Meisenheimer complexes, as shown with the resonance form 3a to 3c:

Baljet reaction Baljet reaction.png
Baljet reaction

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References

  1. The Etymology of Chemical Names: Tradition and Convenience vs. Rationality in Chemical Nomenclature, Walter de Gruyter & Co KG, 2019, ISBN   978-3-11-061124-3
  2. Entry on Baljet-Reaktion . at: Römpp Online . Georg Thieme Verlag, retrieved 2024-11-18.
  3. Bell, Frederick K.; Krantz, John C. (1949-02-01). "Digitalis. VIII. The Baljet Reaction, Digitoxm and Digitoxigenin". Journal of the American Pharmaceutical Association (Scientific ed.). 38 (2): 107–109. doi:10.1002/jps.3030380214. ISSN   0095-9553.
  4. Siegfried Ebel, Hermann J. Roth: Lexikon der Pharmazie 1987, Georg Thieme Verlag Stuttgart, New York, ISBN 3-13-672201-9, S. 80.
  5. "GYLCOSIDES Presented by BAHADUR SINGH HOD - ppt download". slideplayer.com. Retrieved 2024-11-18.