Bankole Johnson

Last updated

Bankole A. Johnson, DSc, MD, MPhil, FRCPsych (born 5 November 1959) is a Nigerian psychiatrist. He served as Alumni Professor and Chairman of the Department of Psychiatry and Neurobehavioral Sciences at the University of Virginia and is known for his research into addiction.

Contents

Johnson's primary area of research expertise is the psychopharmacology of medications for treating addictions, and he is well known in the field for his discovery that topiramate, a gamma-aminobutyric acid (GABA) facilitator and glutamate antagonist, is an effective treatment for alcoholism. [1] [2] Johnson also received national media attention for his appearance in the Home Box Office (HBO) original documentary feature, "Addiction", which won a Governors Award, a special Emmy Award, from the Academy of Television Arts and Sciences. [3] Johnson recently accepted an appointment to join the University of Maryland as the Chairman of Psychiatry and to lead a Brain Science Research Consortium in the neurosciences.


Biography

Johnson was born on 5 November 1959 in Nigeria. Johnson attended King's College in Lagos, Nigeria and received his diploma in 1975. He then went on to Davies' College in Sussex, England followed by the Institute Catholique de Paris in Paris, France. Johnson graduated from the University of Glasgow in Scotland in 1982 with a Medicinae Baccalaureum et Chirurgie Baccalaureum degree. He went on to train in psychiatry at the Royal London and Maudsley and Bethlem Royal Hospitals, and to train in research at the Institute of Psychiatry (University of London). In 1991, Johnson graduated from the University of London with a Master of Philosophy degree in neuropsychiatry. Johnson conducted his doctoral research at Oxford University and obtained a doctorate degree in medicine, Medicinae Doctorem, from the University of Glasgow in 1993. Most recently, in 2004, Johnson earned his Doctor of Science degree in medicine from the University of Glasgow – the highest degree that can be granted in science by a British university.

Johnson joined the faculty at the University of Texas Health Science Center in Houston in 1993 and later became the Deputy chairman for Research and Chief of the Division of Alcohol and Drug Addiction in the Department of Psychiatry at the University of Texas Health Science Center in San Antonio in 1998. In 2001, Johnson received the Dan Anderson Research Award from the Hazelden Foundation for his "distinguished contribution as a researcher who has advanced the scientific knowledge of addiction recovery." [4] In 2002, Johnson received the Distinguished Senior Scholar of Distinction Award from the National Medical Association. Johnson was inducted into the Texas Hall of Fame in 2003 for his contributions to science, mathematics, and technology. [5] On 1 September 2004, Johnson accepted an appointment to serve as Alumni Professor and Chairman of the Department of Psychiatric Medicine at the University of Virginia. [6] Johnson became a fellow of the Royal College of Psychiatrists in 2007. In 2009 Johnson was named associate editor of the editorial board of The American Journal of Psychiatry, and from 2010 to 2011 he served as field editor-in-chief of Frontiers in Psychiatry.

In 2019, Johnson received the R. Brinkley Smithers award from the American Association of Addiction Medicine. [7]

Research

Johnson's research focus is on the neuropsychopharmacology of addiction. His work integrates the neuroscience and behavioural aspects of addiction medicine with the goal of formulating a more thorough understanding of the basis of drug-seeking behaviour and developing effective treatments. Central to his research is the role of and interaction between midbrain monoamine systems with a focus on serotonin, gamma-aminobutyric acid (GABA)/glutamate and dopamine.

Johnson's Journal of the American Medical Association (JAMA) paper, titled "Topiramate for treating alcohol dependence: a randomized controlled trial" and published in 2007, gained national and international media attention. The 14-week US multi-site clinical trial involved 371 male and female alcoholics. Those patients taking topiramate had reduced heavy drinking and showed better results with lowering cholesterol, body mass index, liver enzymes, and blood pressure than those taking the placebo. [8] The study results were featured on Reuters, MSNBC, CBS, ABC, CNN, Fox News, USA Today, the Associated Press, and many other media outlets. [9] [10] [11] [12] [13] [14]

Johnson’s current research involves clinical trials and human laboratory studies, and includes neuroimaging and molecular genetics. He now incorporates neuroimaging evaluations into his drug interaction studies to identify the site-specific effects of abused drugs and to evaluate the effectiveness of potential medications for the treatment of addiction. Current studies include a clinical trial aimed at determining the effectiveness of ondansetron, a serotonin-3 antagonist, for the treatment of subtypes of alcoholics, as well as a human laboratory project trying to elucidate the effects of naltrexone and acamprosate on hepatic and renal function in alcohol-dependent individuals.

Honors and awards

Related Research Articles

<span class="mw-page-title-main">Alcoholism</span> Problematic excessive alcohol consumption

Alcoholism is the continued drinking of alcohol despite it causing problems. Some definitions require evidence of dependence and withdrawal. Problematic use of alcohol has been mentioned in the earliest historical records. The World Health Organization (WHO) estimated there were 283 million people with alcohol use disorders worldwide as of 2016. The term alcoholism was first coined in 1852, but alcoholism and alcoholic are sometimes considered stigmatizing and to discourage seeking treatment, so diagnostic terms such as alcohol use disorder or alcohol dependence are often used instead in a clinical context.

<span class="mw-page-title-main">Topiramate</span> Medication used to treat epilepsy and migraine

Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. It has also been used in alcohol dependence and essential tremor. For epilepsy this includes treatment for generalized or focal seizures. It is taken orally.

<span class="mw-page-title-main">Abram Hoffer</span> Canadian biochemist

Abram Hoffer was a Canadian biochemist, physician, and psychiatrist known for his "adrenochrome hypothesis" of schizoaffective disorders. According to Hoffer, megavitamin therapy and other nutritional interventions are potentially effective treatments for cancer and schizophrenia. Hoffer was also involved in studies of LSD as an experimental therapy for alcoholism and the discovery that high-dose niacin can be used to treat high cholesterol and other dyslipidemias. Hoffer's ideas about megavitamin therapy to treat mental illness are not accepted by the medical community.

Marc Galanter is Professor of Psychiatry at New York University School of Medicine and has served as the Founding Director of the Division of Alcoholism and Drug Abuse. His studies have addressed family therapy for substance abuse, pharmacologic treatment for addiction, and Twelve Step recovery for addiction. He is an author of over 200 peer-reviewed articles. He chairs Twelve Step Interest Groups in AAAP, ASAM, and the International Society of Addiction Medicine and teaches at the New York University School of Medicine.

Addiction medicine is a medical subspecialty that deals with the diagnosis, prevention, evaluation, treatment, and recovery of persons with addiction, of those with substance-related and addictive disorders, and of people who show unhealthy use of substances including alcohol, nicotine, prescription medicine and other illicit and licit drugs. The medical subspecialty often crosses over into other areas, since various aspects of addiction fall within the fields of public health, psychology, social work, mental health counseling, psychiatry, and internal medicine, among others. Incorporated within the specialty are the processes of detoxification, rehabilitation, harm reduction, abstinence-based treatment, individual and group therapies, oversight of halfway houses, treatment of withdrawal-related symptoms, acute intervention, and long term therapies designed to reduce likelihood of relapse. Some specialists, primarily those who also have expertise in family medicine or internal medicine, also provide treatment for disease states commonly associated with substance use, such as hepatitis and HIV infection.

The modern disease theory of alcoholism states that problem drinking is sometimes caused by a disease of the brain, characterized by altered brain structure and function. Today, alcohol use disorder (AUD) is used as a more scientific and suitable approach to alcohol dependence and alcohol-related problems.

<span class="mw-page-title-main">George Koob</span> American academic

George F. Koob is a Professor and former Chair of the Committee on the Neurobiology of Addictive Disorders at the Scripps Research Institute and Adjunct Professor of Psychology, Psychiatry, and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego. In 2014 he became the director of the National Institute on Alcohol Abuse and Alcoholism.

<span class="mw-page-title-main">Nora Volkow</span> American physician

Nora D. Volkow is a Mexican-American psychiatrist. She is currently the director of the National Institute on Drug Abuse (NIDA), which is part of the National Institutes of Health (NIH).

Olivier Ameisen was a French-American cardiologist who wrote a best-selling book about curing alcoholism using the drug baclofen.

David M. McDowell (1963–2014) was an American psychiatrist, author and creative consultant. He co-founded the Substance Treatment and Research Service at Columbia University and served as its medical director. He also founded Columbia's Buprenorphine Program, the first such treatment program for opiate addiction in the United States, which according to The New York Times had an 88% success rate. His scholarly work has focused on co-occurring psychiatric disorders and substance abuse problems, particularly club drugs and marijuana. McDowell's book Substance Abuse: From Principles to Practice, is one of the more highly regarded and accessible books on the subject, and is excerpted in the American Psychiatric Association's textbook on substance abuse treatment.

Kevin Joseph Michael Gournay CBE FMedSci FRCN FRSM FRCPsych (Hon) PhD RN CSci Cert CBT is a registered psychologist, chartered scientist and a registered nurse by background. He is an emeritus professor at the Institute of Psychiatry, Psychology and Neuroscience; King's College London. He was a consultant psychologist at the Priory Hospital North London; retiring in December 2018. He then returned to clinical work as part of the national response to COVID19; retiring once more in 2023. He is currently an Honorary Professor at the Matilda Centre; University of Sydney. His work in Australia spans 30 years to the present and focusses on the combination of mental health problems and substance use. During the COVID19 pandemic he contributed to research on the impacts of COVID19 on mental health. He has been responsible over many years for a very wide range of research, policy and practice development in mental health care. He also works as an Expert Witness; he has provided reports on more than 300 suicides; 20 homicides and hundreds of reports on people who have suffered the consequences of traumatic events, including accidents, terrorist related incidents, natural disasters, war related events and stillbirth and perinatal death. He has also provided numerous reports on patients receiving care and treatment in high secure and Medium secure settings, including Broadmoor, Rampton and Ashworth hospitals

<span class="mw-page-title-main">Lee Robins</span> American professor

Lee Nelken Robins was an American professor of social science in psychiatry and a leader in psychiatric epidemiology research. She was affiliated with the Washington University in St. Louis for more than 50 years from 1954 until 2007.

Karl Murdock Bowman was a pioneer in the study of psychiatry. From 1944 to 1946 he was the president of the American Psychiatric Association. His work in alcoholism, schizophrenia, and homosexuality is particularly often cited.

Addiction psychiatry is a medical subspecialty within psychiatry that focuses on the evaluation, diagnosis, and treatment of people who have one or more disorders related to addiction. This may include disorders involving legal and illegal drugs, gambling, sex, food, and other impulse control disorders. Addiction psychiatrists are substance use disorder experts. Growing amounts of scientific knowledge, such as the health effects and treatments for substance use disorders, have led to advancements in the field of addiction psychiatry. These advancements in understanding the neurobiology of rewarding behavior, along with federal funding, has allowed for ample opportunity for research in the discipline of addiction psychiatry. Addiction psychiatry is an expanding field, and currently there is a high demand for substance use disorder experts in both the private and public sector.

Igor Grant is an American psychiatrist. He is Distinguished Professor in the Department of Psychiatry in the School of Medicine at the University of California, San Diego. He is Director of the HIV Neurobehavioral Research Program (HNRP) and the Center for Medicinal Cannabis Research (CMCR). Grant is the founding Editor of the Journal of the International Neuropsychological Society and founding co-editor of the journal AIDS and Behavior. His work focuses on effects of HIV and drug use, particularly alcohol, medical marijuana, and methamphetamine.

Joanna Moncrieff is a British psychiatrist and academic. She is Professor of Critical and Social Psychiatry at University College London and a leading figure in the Critical Psychiatry Network. She is a prominent critic of the modern 'psychopharmacological' model of mental disorder and drug treatment, and the role of the pharmaceutical industry. She has written papers, books and blogs on the use and over-use of drug treatment for mental health problems, the mechanism of action of psychiatric drugs, their subjective and psychoactive effects, the history of drug treatment, and the evidence for its benefits and harms. She also writes on the history and politics of psychiatry more generally. Her best known books are The Myth of the Chemical Cure and The Bitterest Pills.

<span class="mw-page-title-main">Charles P. O'Brien</span> American research scientist, medical educator (born 1939)

Charles P. O'Brien is a research scientist, medical educator and a leading expert in the science and treatment of addiction. He is board certified in neurology, psychiatry and addiction psychiatry. He is currently the Kenneth E. Appel Professor of Psychiatry, and vice chair of psychiatry, in the Perelman School of Medicine at the University of Pennsylvania.

Nancy M. Petry was a psychologist known for her research on behavioral treatments for addictive disorders, behavioral pharmacology, impulsivity and compulsive gambling. She was Professor of Medicine at the University of Connecticut Health Center. Petry served as a member of the American Psychiatric Association Workgroup on Substance Use Disorders for the DSM-5 and chaired the Subcommittee on Non-Substance Behavioral Addictions. The latter category includes Internet addiction disorder and problem gambling. She also served as a member of the Board of Advisors of Children and Screens: Institute of Digital Media and Child Development.

John F. Kelly is an American-based researcher and professor of addiction medicine at Harvard Medical School. He is the Founder and Director of the Massachusetts General Hospital Recovery Research Institute, Associate Director of the MGH Center for Addiction Medicine, and Program Director of the MGH Addiction Recovery Management Service.

<span class="mw-page-title-main">Joseph R. Volpicelli</span> American psychiatrist

Joseph R. Volpicelli is an American psychiatrist, research scientist, medical academic, and expert in the treatment of addictive disorders. He is Professor Emeritus, Perelman School of Medicine at the University of Pennsylvania. He is board certified in neurology, psychiatry and addiction psychiatry. He currently is Medical Director at Volpicelli Center, an out-patient addiction treatment facility in Plymouth Meeting, Pennsylvania, as well as the Executive Director at Institute of Addiction Medicine, a non-profit research entity also in Plymouth Meeting, Pennsylvania.

References

  1. "www.healthsystem.virginia.edu/internet/psychiatric/staffandfaculty/research.cfm?uva_id=bj4x&hideintro=1".
  2. Johnson BA, Ait-Daoud N, Bowden CL, et al. 2003. Oral topiramate for treatment of alcohol dependence: A randomised controlled trial. Lancet 361, 1677–1685
  3. "NIH received two emmy awards for the addiction project" 16 September 2007. http://www.medicalnewstoday.com/articles/82613.php
  4. "www.hbo.com/addiction/thefilm/bios/6423_Bankole_Johnson.html".
  5. "Drs. Bankole Johnson, Wen-Hwa Lee join luminaries in Texas Hall of Fame". February 2003. http://www.uthscsa.edu/mission/article.asp?id=123
  6. "Dr. Bankole Johnson, new chairman of Psychiatric Medicine". 2004. "Dr. Bankole Johnson, new chairman of psychiatric medicine: 09-03-2004". Archived from the original on 24 July 2008. Retrieved 2008-11-10.
  7. "Dr. Bankole Johnson ( Miami/Fort Lauderdale )". Haute Living . Retrieved 28 September 2020.
  8. Johnson BA, Rosenthal N, Capece JA, et al. 2008. Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial. Archives of Internal Medicine. 168: 1188–1199.
  9. "A Pill to Cure Alcoholism?" . Retrieved 22 June 2023.
  10. "Topiramate may help treat alcohol dependence" 10 October 2007. http://www.medicalnewstoday.com/printerfriendlynews.php?newsid=85202
  11. "Study: Migraine pill helps some alcoholics taper off" 9 October 2007. "Study: Migraine pill helps some alcoholics taper off - CNN.com". CNN . Archived from the original on 19 December 2008. Retrieved 2008-11-10.
  12. "Pill helps alcoholics taper off drinking" 9 October 2007. http://www.foxnews.com/printer_friendly_wires/2007Oct09/0,4675,AlcoholismPill,00.html
  13. "Migraine Drug May Treat Alcoholism, Too". ABC News. Retrieved 22 June 2023.
  14. "Migraine pill helps curb drinking without detox: New approach called promising, but side effects still a problem, study finds" 9 October 2007.