Modafinil, sold under the brand name Provigil among others, is a wakefulness-promoting medication used primarily to treat narcolepsy. Modafinil is also approved for stimulating wakefulness in people with sleep apnea and shift work sleep disorder. It is taken by mouth. Modafinil is not approved by the US Food and Drug Administration (FDA) for use in people under age 17.
Sanofi S.A. is a French multinational pharmaceutical and healthcare company headquartered in Paris, France. The corporation was established in 1973 and merged with Synthélabo in 1999 to form Sanofi-Synthélabo. In 2004, Sanofi-Synthélabo merged with Aventis and renamed to Sanofi-Aventis, which were each the product of several previous mergers. It changed its name back to Sanofi in May 2011. The company is a component of the Euro Stoxx 50 stock market index. In 2023, the company’s seat in Forbes Global 2000 was 89.
Medtronic plc is an Irish medical device company. The company's operational and executive headquarters are in Minneapolis, Minnesota, and its legal headquarters are in Ireland due to its acquisition of Irish-based Covidien in 2015. While it primarily operates in the United States, it operates in more than 150 countries and employs over 90,000 people. It develops and manufactures healthcare technologies and therapies.
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity such as from a spinal cord injury or multiple sclerosis. It may also be used for hiccups and muscle spasms near the end of life, and off-label to treat alcohol use disorder or opioid withdrawal symptoms. It is taken orally or by intrathecal pump. It is also sometimes used transdermally in combination with gabapentin and clonidine prepared at a compounding pharmacy.
Ipsen is a French biopharmaceutical company headquartered in Paris, France, with a focus on transformative medicines in three therapeutic areas: oncology, rare disease and neuroscience. Ipsen is one of the world's top 15 biopharmaceutical companies in terms of oncology sales.
Iduronidase, sold as Aldurazyme, is an enzyme with the systematic name glycosaminoglycan α-L-iduronohydrolase. It catalyses the hydrolysis of unsulfated α-L-iduronosidic linkages in dermatan sulfate.
Quadient is an international company specialized in mailing equipment, business process automation and customer experience management. It was originally founded as Neopost. As of 2019, the company had about 5,693 employees and annual sales of €1.14 billion. Its products and services are sold in about 90 countries. Quadient is a company listed on the Euronext Paris market. Its stock ticker is QDT.
Abiomed, Inc. is a medical device technology company that operates as a stand-alone business within Johnson & Johnson's MedTech Segment. Abiomed develops and manufactures temporary external and implantable mechanical circulatory support devices. The company is headquartered in Danvers, Massachusetts with additional offices in Woburn, Baltimore, Berlin, Aachen, and Tokyo.
Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis, systemic juvenile idiopathic arthritis, a severe form of arthritis in children, and COVID‑19. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer. Tocilizumab was jointly developed by Osaka University and Chugai, and was licensed in 2003 by Hoffmann-La Roche.
Eurazeo is a French private equity firm and investment group headquartered in Paris. With a diversified portfolio of €35 billion in assets under management, including €23 billion from third parties, invested in more than 600 companies.
Ibalizumab, sold under the brand name Trogarzo, is a non-immunosuppressive humanised monoclonal antibody that binds CD4, the primary receptor for HIV, and inhibits HIV from entering cells. It is a post-attachment inhibitor, blocking HIV from binding to the CCR5 and CXCR4 co-receptors after HIV binds to the CD4 receptor on the surface of a CD4 cell. Post-attachment inhibitors are a subclass of HIV drugs called entry inhibitors.
Withings is a French consumer electronics company headquartered in Issy-les-Moulineaux, France. It also has offices in Boston, Massachusetts, USA, and Hong Kong, and distributes its products worldwide. Withings is known for design and innovation in connected devices, such as the first Wi-Fi scale on the market, an FDA-cleared blood pressure monitor, a smart sleep system, and a line of automatic activity tracking watches. It also provides B2B services for healthcare providers and researchers.
Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa. Specifically, it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. It is used as an alternative to warfarin and does not require monitoring by blood tests or dietary restrictions. It is taken by mouth.
Newfund is a venture capital firm focused on early stage investment in France and the United States. Founded in 2008, it had raised more than 230 million euros as of September 2018, mostly from entrepreneurs, business leaders, and family offices. It typically invests between €500,000 and €2m per company. It has repeatedly been listed among the most significant venture capital funds in France.
Bertin Nahum is a French-Beninese entrepreneur in surgical robotics. He is the CEO and co-founder of Quantum Surgical based in Montpellier, France. He previously founded in 2002 Medtech S.A; specialized in the design, development and marketing of surgical assistance robots that was sold to Zimmer Biomet in 2016.
Believe is a global digital music company headquartered in France. Believe has several brands including TuneCore, Nuclear Blast, Naïve, Groove Attack, Play Two and AllPoints.
Equativ is a French advertising technology company. Created in 2001 as part of Aufeminin, it was bought by private-equity fund Cathay Capital in 2015, and then by private-equity fund Capital Croissance for a secondary LBO in 2021. It operates mostly in the US, Europe, Latin America and Asia.
The Z Event is a francophone charity project created by Adrien Nougaret and Alexandre Dachary whose goal is to bring together French streamers to collect donations that will support a charity. It is hosted on the Twitch streaming platform.
Owkin is an AI biotech company that uses artificial intelligence to identify new treatments, optimize clinical trials and develop AI diagnostics. The company uses federated learning, a type of privacy preserving technology, to access multimodal patient data from academic institutions and hospitals to train its AI models for drug discovery, development, and diagnostics. Owkin has collaborated with pharmaceutical companies around the world to improve their therapeutic programs.
SWILE is a French app-based company that focuses on improving the employee experience. Among others, the platform offers meal vouchers, gift vouchers, mobility vouchers, and business travel solutions.
