Carol Brayne

Carol Elspeth Goodeve Brayne CBE is a British epidemiologist, academic, physician and medical researcher. Her current position is Professor Emeritus and Senior Visiting Fellow in the Department of Psychiatry at University of Cambridge.

Early life, family and education

Brayne received a degree in medicine from the Royal Free Hospital School of Medicine, University of London, ^[1] in 1981. ^[2] She subsequently earned a masters of science in epidemiology. ^[3]

Career

Brayne was the Professor of Public Health Medicine at the University of Cambridge from 2001 to 2024. ^[3] She joined Cambridge in 1985. ^[3] She has been Chair of Wellcome's Population and Public Health Review Group. ^[4] She was Director of the Cambridge Institute of Public Health. ^[3] She has been a special advisor for the Royal College of Physicians and a senior investigator at the National Institute for Health Research (NIHR). ^[1]

Brayne has worked for the National Health Service. ^[2] She also spent six months as a visiting fellow in Australia in 1997. ^[2]

Honors and awards

In the 2017 Birthday Honours, ^[3] Brayne was appointed CBE, "[f]or services to Public Health Medicine". ^{[4] [5]}

Personal life

Brayne and her husband have raised four children. ^[2]

Selected publications

• Wharton SB, Simpson JE, Brayne C, et al. (January 2015). "Age-Associated White Matter Lesions: The MRC Cognitive Function and Ageing Study". Brain Pathol. 25 (1): 35–43. doi:10.1111/bpa.12219. PMC   8029351 . PMID   25521175.
• Norton S, Matthews FE, Barnes DE, et al. (August 2014). "Potential for primary prevention of Alzheimer's disease: an analysis of population-based data" (PDF). Lancet Neurol. 13 (8): 788–94. doi:10.1016/S1474-4422(14)70136-X. PMID   25030513.
• D'Alton S, Hunter S, Whitehouse P, et al. (2014). "Adapting to dementia in society: a challenge for our lifetimes and a charge for public health". J Alzheimers Dis. 42 (4): 1151–63. doi:10.3233/JAD-140213. PMID   25024316.
• Stephan BC, Minett T, Muniz Terrera G, et al. (January 2015). "Dementia prediction for people with stroke in populations: is mild cognitive impairment a useful concept?". Age Ageing. 44 (1): 78–83. doi:10.1093/ageing/afu085. PMC   4255614 . PMID   25002454.
• Noel-Storr AH, McCleery JM, Richard E, et al. (July 2014). "Reporting standards for studies of diagnostic test accuracy in dementia: The STARDdem Initiative". Neurology . 83 (4): 364–73. doi:10.1212/WNL.0000000000000621. PMC   4115600 . PMID   24944261.
• Escott-Price V, Bellenguez C, Wang LS, et al. (12 June 2014). "Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease". PLOS ONE. 9 (6): e94661. Bibcode:2014PLoSO...994661E. doi: 10.1371/journal.pone.0094661 . PMC   4055488 . PMID   24922517.
• Garwood CJ, Simpson JE, Al Mashhadi S, et al. (December 2014). "DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort". Neuropathol Appl Neurobiol. 40 (7): 802–14. doi:10.1111/nan.12156. PMID   24861546.
• Janaway BM, Simpson JE, Hoggard N, et al. (April 2014). "Brain haemosiderin in older people: pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds". Neuropathol Appl Neurobiol. 40 (3): 258–69. doi:10.1111/nan.12062. PMC   4282337 . PMID   23678850.
• Wimo A, Ballard C, Brayne C, et al. (March 2014). "Health economic evaluation of treatments for Alzheimer's disease: impact of new diagnostic criteria". J Intern Med. 275 (3): 304–16. doi:10.1111/joim.12167. PMID   24605810.
• Perales J, Cosco TD, Stephan BC, et al. (February 2014). "Health-related quality of life in the Cambridge City over-75s Cohort (CC75C): development of a dementia-specific scale and descriptive analyses". BMC Geriatr. 10 (14): 18. doi: 10.1186/1471-2318-14-18 . PMC   3922243 . PMID   24512291.
• Lima TA, Adler AL, Minett T, et al. (March 2014). "C-reactive protein, APOE genotype and longitudinal cognitive change in an older population". Age Ageing. 43 (2): 289–92. doi:10.1093/ageing/aft193. PMC   3927773 . PMID   24305621.
• Liu G, Yao L, Liu J, et al. (April 2014). "Cardiovascular disease contributes to Alzheimer's disease: evidence from large-scale genome-wide association studies". Neurobiology of Aging. 35 (4): 786–92. doi:10.1016/j.neurobiolaging.2013.10.084. PMID   24231519.
• Sachdev PS, Lipnicki DM, Kochan NA, et al. (November 2013). "COSMIC (Cohort Studies of Memory in an International Consortium): an international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups". BMC Neurol. 6 (13): 165. doi: 10.1186/1471-2377-13-165 . PMC   3827845 . PMID   24195705.
• Lambert JC, Ibrahim-Verbaas CA, Harold D, et al. (December 2013). "Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease". Nat Genet. 45 (12): 1452–8. doi:10.1038/ng.2802. PMC   3896259 . PMID   24162737.
• Wardlaw JM, Smith EE, Biessels GJ, et al. (August 2013). "Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration". Lancet Neurol. 12 (8): 822–38. doi:10.1016/S1474-4422(13)70124-8. PMC   3714437 . PMID   23867200.

References

1. "Professor Carol Brayne". phpc.cam.ac.uk. Department of Public Health and Primary Care, University of Cambridge. Archived from the original on 1 May 2019. Retrieved 28 June 2017.
2. Pincock, Stephen (19 July 2008). "Carol Brayne: studying dementia in the brain and in populations" (PDF). The Lancet . 372 (9634): 197. doi:10.1016/S0140-6736(08)61057-0. PMID   18640444 . Retrieved 4 February 2025.
3. "Carol Brayne". cpc.cam.ac.uk. Cambridge Public Health, University of Cambridge. 12 December 2022. Retrieved 4 February 2025.
4. "Awards for Wellcome community in Queen's Birthday Honours". wellcome.ac.uk. Wellcome. 19 June 2017. Retrieved 28 June 2017.
5. "Cambridge scientists among those honoured by Queen | Anglia". itv.com. ITV News. 16 June 2017. Retrieved 28 June 2017.