Celine Marmion

Last updated
Celine J. Marmion
Alma mater University of Surrey (PhD)
Kingston University (PGCE)
Scientific career
Institutions St Mary's University, Twickenham
Royal College of Surgeons in Ireland

Celine J. Marmion is a Professor of Chemistry at the Royal College of Surgeons in Ireland and President of the Institute of Chemistry of Ireland. She is a Fellow of the Royal Society of Chemistry and the Institute of Chemistry of Ireland. Marmion is involved with the design of new chemotherapeutic drugs.

Contents

Early life and education

Marmion earned her doctoral degree at the University of Surrey in 1994. [1] Her PhD research involved investigations into vanadium complexes and nitrogen fixation. In 1994 Marmion was appointed as a lecturer at St Mary's University, Twickenham, where she worked until 1995. [2] She returned to study in 1995, and earned a Postgraduate Certificate in Education (PGCE) at Kingston University. [3]

Research and career

In 1997 Marmion joined Royal College of Surgeons in Ireland as a lecturer in the Department of Chemistry. [2] She was promoted to Associate Professor in 2013 and Professor in 2018. Her research considers the design of metal-based chemotherapeutic drugs. In particular, this has included the design of targeted PtIV prodrugs. [4] [5] Immunodeficient cancer patients are at risk of developing infections, which occasionally require antimicrobial prophylaxis. To better serve these patients Marmion developed a family of metallo-antibiotics, based on a Cu-N,N-framework, which can bind to DNA, has DNA oxidant properties and has antiproliferative and antimicrobial properties. [6] Her research has been supported by the Science Foundation Ireland (SFI) to create a prodrug strategy for multi-modal chemotherapeutics. [7]

Awards and honours

Her awards and honours include:

Selected publications

Her publications include:

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References

  1. ↑ Dublin, T. U. "TU Dublin News". www.dit.ie. Retrieved 2020-01-13.
  2. 1 2 "Dr Celine Marmion – Biography". www.ucd.ie. Retrieved 2020-01-13.
  3. 1 2 "Profile". www.rcsi.com. Retrieved 2020-01-13.
  4. ↑ Kenny, Reece G.; Chuah, Su Wen; Crawford, Alanna; Marmion, Celine J. (2017). "Platinum(IV) Prodrugs – A Step Closer to Ehrlich's Vision?". European Journal of Inorganic Chemistry. 2017 (12): 1596–1612. doi: 10.1002/ejic.201601278 . ISSN   1099-0682.
  5. ↑ Kenny, Reece G.; Marmion, Celine J. (2019-01-23). "Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens?". Chemical Reviews. 119 (2): 1058–1137. doi:10.1021/acs.chemrev.8b00271. ISSN   0009-2665. PMID   30640441.
  6. ↑ Ude, Ziga; Kavanagh, Kevin; Twamley, Brendan; Pour, Milan; Gathergood, Nicholas; Kellett, Andrew; Marmion, Celine J. (2019-06-18). "A new class of prophylactic metallo-antibiotic possessing potent anti-cancer and anti-microbial properties". Dalton Transactions. 48 (24): 8578–8593. doi:10.1039/C9DT00250B. ISSN   1477-9234. PMID   30946409.
  7. ↑ Harrington, James (2018-10-30). "€3.5m investment in research commercialisation unveiled". Engineers Journal. Retrieved 2020-01-13.
  8. 1 2 3 "Speakers – Celebrating Research – Past, Present, Future – Royal College Surgeons in Ireland". rcsi.ie. Retrieved 2020-01-13.
  9. ↑ Kenny, Reece G.; Chuah, Su Wen; Crawford, Alanna; Marmion, Celine J. (2017). "Platinum(IV) Prodrugs – A Step Closer to Ehrlich's Vision?". European Journal of Inorganic Chemistry. 2017 (12): 1596–1612. doi: 10.1002/ejic.201601278 . ISSN   1099-0682.
  10. ↑ "RCSI Dean's Academic Award". www.rcsi.ie. Retrieved 2020-01-13.
  11. ↑ inmedlogin. "Past Recipients". Irish Network of Healthcare Educators. Retrieved 2020-01-13.
  12. ↑ "Annual General Meeting 2017 | Photo gallery | Institute of Chemistry of Ireland". www.chemistryireland.org. Retrieved 2020-01-13.
  13. ↑ "Meet…". EuChemS Newsletters. 2019-11-06. Retrieved 2020-01-13.
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