The Center of Expertise on Gender Dysphoria (CEGD), or the Kennis- en Zorgcentrum Genderdysforie (KZcG), is a transgender clinic at Amsterdam University Medical Centers, location VUmc in Amsterdam, Netherlands. [1] [2] It opened in 1975 [3] and is one of the largest transgender clinics and research institutes in the world. [1] [2] Initially for adults only, [4] from 1987 onwards, a practice dedicated to adolescents opened in Utrecht. [5] :301 The children's clinic merged with the adult clinic in 2002, moving to Amsterdam. [5] :301-302; [Note 1]
As of 2021, it has treated about 10,000 transgender people since it opened almost 50 years previously. [2] The clinic was first headed by Louis Gooren. [6]
Hormone therapy for transgender women was initially done using high-dose estrogen therapy with oral estrogens. Progestogens were also sometimes included. [7] The antiandrogen and progestogen cyproterone acetate was first used in transgender women by 1977. [8] [9] [10] Its use was standard at the CEGD by 1985. [11] [12]