Cephalosporolide

Last updated December 11, 2025

Chemical structures of selected cephalosporolides

Cephalosporolide B

Cephalosporolide C

Cephalosporolide D

Cephalosporolide E

Cephalosporolide F

Cephalosporolide G

Cephalosporolides are novel lactones isolated from marine Penicillium .^[1]

Because of their unusual chemical structures and potential pharmacological effects, several laboratory syntheses for various cephalosporolides have been developed.^[2]^[3]^[4]

References

↑ Halle, M. B.; Fernandes, R. A. (2016). "Total Synthesis of Marine Natural Products: Cephalosporolides" . Asian Journal of Organic Chemistry. 5 (7): 839–854. doi:10.1002/ajoc.201600208.
↑ Halle, Mahesh B.; Fernandes, Rodney A. (2016). "Total Synthesis of Marine Natural Products: Cephalosporolides". Asian Journal of Organic Chemistry. 5 (7): 839–854. doi:10.1002/ajoc.201600208.
↑ Yao, Hongliang; Wang, Jian; Tong, Rongbiao (2017). "Recent Developments in Total Syntheses of Cephalosporolides, Penisporolides, and Ascospiroketals". The Chemical Record. 17 (11): 1109–1123. doi:10.1002/tcr.201700001. PMID 28272766.
↑ Harkala, Karna Ji; Eppakayala, Laxminarayana; Maringanti, Thirumala Chary (2014). "Stereoselective synthesis of (-) Cephalosporolide D" (PDF). European Journal of Chemistry. 5: 127–132. doi:10.5155/eurjchem.5.1.127-132.1002.

External links

Li, X.; Yao, Y.; Zheng, Y.; Sattler, I.; Lin, W. (2007). "Cephalosporolides H and I, Two Novel Lactones from a Marine-Derived Fungus, Penicillium sp". Archives of Pharmacal Research. 30 (7): 812–815. doi:10.1007/BF02978829. PMID 17703730.
ChemSpider - Cephalosporolide H
ChemSpider - Cephalosporolide I

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[1] Halle, M. B.; Fernandes, R. A. (2016). "Total Synthesis of Marine Natural Products: Cephalosporolides" . Asian Journal of Organic Chemistry. 5 (7): 839–854. doi:10.1002/ajoc.201600208.

[2] Halle, Mahesh B.; Fernandes, Rodney A. (2016). "Total Synthesis of Marine Natural Products: Cephalosporolides". Asian Journal of Organic Chemistry. 5 (7): 839–854. doi:10.1002/ajoc.201600208.

[3] Yao, Hongliang; Wang, Jian; Tong, Rongbiao (2017). "Recent Developments in Total Syntheses of Cephalosporolides, Penisporolides, and Ascospiroketals". The Chemical Record. 17 (11): 1109–1123. doi:10.1002/tcr.201700001. PMID 28272766.

[4] Harkala, Karna Ji; Eppakayala, Laxminarayana; Maringanti, Thirumala Chary (2014). "Stereoselective synthesis of (-) Cephalosporolide D" (PDF). European Journal of Chemistry. 5: 127–132. doi:10.5155/eurjchem.5.1.127-132.1002.

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