Charles H. Langely

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Charles H. Langley, often known as "Chuck", is an American geneticist and evolutionary biologist who is currently a Distinguished Professor of Genetics at the University of California, Davis. His work focuses on the evolutionary forces shaping genetic variation, including mutation, recombination, natural selection, and linkage effects. He is known for integrating theoretical, computational, and empirical approaches in population genetics and genomics.

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Early life and education

Langley earned his Ph.D. from the University of Texas at Austin in 1971, and subsequently conducted postdoctoral research at the University of Wisconsin–Madison. [1]

Career

Langley began his career at the National Institute of Environmental Health Sciences (NIEHS) in Research Triangle Park, North Carolina, before joining the University of California, Davis in 1989. [2]

At UC Davis, Langley’s research has centered on evolutionary genetics and population genomics, with particular emphasis on the structure of genetic variation in natural populations of Drosophila . He contributed to the development of approaches to infer recombination rates, detect selection, and interpret genome-wide variation. Langley was among the first to propose and document the existence of centromere-spanning haplotypes (cenhaps) in both humans and Drosophila. [3]

Awards and honors

Mentorship and influence

Langley has mentored numerous students and postdoctoral researchers in evolutionary genetics. Among his notable doctoral students is Manyuan Long, known for research on the origin and evolution of new genes. [6]

Selected research areas

References

  1. ↑ "Charles H. Langley". Simons Institute for the Theory of Computing. Retrieved 17 October 2025.
  2. ↑ "Geneticist to deliver top senate lecture". University of California, Davis. 10 April 2009. Retrieved 17 October 2025.
  3. ↑ "Charles Langley, Ph.D." Simons Foundation Autism Research Initiative. 3 August 2022. Retrieved 17 October 2025.
  4. ↑ Drake, John (2000). "The 1999 Genetics Society of America Medal: Charles H. Langley". Genetics. 154 (1): 1–3. doi:10.1093/genetics/154.1.3. PMC   1460899 . PMID   10681181.
  5. ↑ "Charles Hunt Langley". American Academy of Arts and Sciences. 25 September 2025. Retrieved 17 October 2025.
  6. ↑ Long, Manyuan; Langley, Charles H. (1993-04-02). "Natural Selection and the Origin of jingwei , a Chimeric Processed Functional Gene in Drosophila" . Science. 260 (5104): 91–95. Bibcode:1993Sci...260...91L. doi:10.1126/science.7682012. ISSN   0036-8075. PMID   7682012.
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