Christodoulos I. Stefanadis

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Christodoulos I. Stefanadis is Professor of Cardiology in the Medical School of the University of Athens. Professor of Medicine, Department of Medicine, Division of Cardiology, Emory University, Atlanta U.S.A.Professor of Internal Medicine, Cardiology, Yale University , New Haven, Connecticut, USA. He has been recognised as the top researcher in the field of Cardiovascular medicine in the last 20 years with the most original research publications in peer review journals. [1] Some of his main research interests include coronary heart disease, detection and treatment of vulnerable atheromatic plaque, aortic elastic properties, mitral valve disease, interventional treatment of resistant hypertension and designing many catheter types used for various diagnostic and therapeutic interventional procedures. [2]

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He is also a member of the Hellenic Parliament from New Democracy.

Biography

Christodoulos Stefanadis was born in Ikaria May 31,1947, Greece and attended the University of Athens Medical School from which he graduated in 1971. He completed his residency in Cardiology at the Cardiology Department of the University of Athens (1978), followed by a PhD in Athens Medical School (1981). He has been Professor of Cardiology since 2002 and Director of the 1st Department of Cardiology since 2003. [3] He has held the positions of Dean of Athens Medical School (2007–2011), President of the Hellenic Society of Cardiology (1997–1999 & 2007–2009), Board Member of the Hellenic Heart Foundation (1995–present), [4] Professor of Medicine, Department of Medicine, Division of Cardiology, Emory University, Atlanta U.S.A., [5] Professor of Internal Medicine, Cardiology, Yale University, New Haven, Connecticut, USA (July 2014–). [6]

Research

One of his several research activities include designing of at least 10 prototype cardiac catheters which were applied in various diagnostic and therapeutic interventions. Early in his career he developed the technique of retrograde non-transeptal mitral balloon valvuloplasty which has been used internationally for the interventional treatment of mitral stenosis, introduced the idea of covering metallic stents by non-thrombotic material and he developed covered stents by autologous vascular (arterial or vein) grafts. He subsequently made studies on the elastic properties of aorta and the function of left atrium. A large part of his research efforts was devoted to experimental and clinical studies on coronary heart disease, such as estimation of thermal heterogeneity of human atherosclerotic plaques using a special catheter with a thermistor tip, external non-invasive heating of stented arterial segments, and evolution and application of bevacizumab-eluting stent for the inhibition of microvessel growth in unstable atherosclerotic plaques. [3] He has been worked lately on invasive treatment methods of resistant hypertension by novel sympathetic denervation techniques of the renal arteries (chemical denervation, barodenervation). [7] He has presented his research results by more than 3,500 abstracts in international scientific conferences and has given over 260 lectures as invited speaker internationally.

Publications

Stefanadis has published 1685 research articles in international peer reviewed medical journals. [8] The h-index factor for these publications is 136. [9] According to Publons research database of Clarivate analytics, Professor Stefanadis holds the 1st place amongst researchers and authors internationally, in terms of number of verified publications with 3079 published papers. He is the editor of 6 medical books of international publications and has written chapters in 13 international books. He is Chief Editor of the Hellenic Journal of Cardiology, [10] and member of the editorial board and reviewer in Greek and International Scientific Journals.

Journal of Clinical and Diagnostic Research has published an "Analysis of Global Research Trends in

Cardiology Over the Last two Decades" listing Christodoulos Stefanadis at the first rank among top authors for clinical cardiology research. [11]

Honors and awards

Stefanadis was awarded the title of "Elite Reviewer" by the scientific journal Journal of the American College of Cardiology (JACC) in recognition of his whole contribution to the journal's publications (2005) [12] and the international journal Clinical Cardiology dedicated a special honorary article to him entitled "Profiles in Cardiology" in a 2007 issue. [3]

The American College of Cardiology awarded him the Simon Dack's Award (2011), which is given annually to the scientist with the most important contribution to the scientific journals of the American College of Cardiology (Journal of the American College of Cardiology, JACC-Cardiovascular Interventions and JACC-Cardiovascular Imaging). [13]

Selected papers

Related Research Articles

<span class="mw-page-title-main">Angioplasty</span> Procedure to widen narrow arteries or veins

Angioplasty, also known as balloon angioplasty and percutaneous transluminal angioplasty (PTA), is a minimally invasive endovascular procedure used to widen narrowed or obstructed arteries or veins, typically to treat arterial atherosclerosis.

<span class="mw-page-title-main">Aortic stenosis</span> Narrowing of the exit of the hearts left ventricle

Aortic stenosis is the narrowing of the exit of the left ventricle of the heart, such that problems result. It may occur at the aortic valve as well as above and below this level. It typically gets worse over time. Symptoms often come on gradually with a decreased ability to exercise often occurring first. If heart failure, loss of consciousness, or heart related chest pain occur due to AS the outcomes are worse. Loss of consciousness typically occurs with standing or exercising. Signs of heart failure include shortness of breath especially when lying down, at night, or with exercise, and swelling of the legs. Thickening of the valve without narrowing is known as aortic sclerosis.

Hypertrophic cardiomyopathy is a condition in which muscle tissues of the heart become thickened without an obvious cause. The parts of the heart most commonly affected are the interventricular septum and the ventricles. This results in the heart being less able to pump blood effectively and also may cause electrical conduction problems. Specifically, within the bundle branches that conduct impulses through the interventricular septum and into the Purkinje fibers, as these are responsible for the depolarization of contractile cells of both ventricles.

<span class="mw-page-title-main">Diastole</span> Part of the cardiac cycle

Diastole is the relaxed phase of the cardiac cycle when the chambers of the heart are refilling with blood. The contrasting phase is systole when the heart chambers are contracting. Atrial diastole is the relaxing of the atria, and ventricular diastole the relaxing of the ventricles.

<span class="mw-page-title-main">Aortic regurgitation</span> Medical condition

Aortic regurgitation (AR), also known as aortic insufficiency (AI), is the leaking of the aortic valve of the heart that causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle. As a consequence, the cardiac muscle is forced to work harder than normal.

<span class="mw-page-title-main">Interventional cardiology</span>

Interventional cardiology is a branch of cardiology that deals specifically with the catheter based treatment of structural heart diseases. Andreas Gruentzig is considered the father of interventional cardiology after the development of angioplasty by interventional radiologist Charles Dotter.

Intravascular ultrasound (IVUS) or intravascular echocardiography is a medical imaging methodology using a specially designed catheter with a miniaturized ultrasound probe attached to the distal end of the catheter. The proximal end of the catheter is attached to computerized ultrasound equipment. It allows the application of ultrasound technology, such as piezoelectric transducer or CMUT, to see from inside blood vessels out through the surrounding blood column, visualizing the endothelium of blood vessels.

<span class="mw-page-title-main">Aortic valvuloplasty</span>

Aortic valvuloplasty, also known as balloon aortic valvuloplasty (BAV), is a procedure used to improve blood flow through the aortic valve in conditions that cause aortic stenosis, or narrowing of the aortic valve. It can be performed in various patient populations including fetuses, newborns, children, adults, and pregnant women. The procedure involves using a balloon catheter to dilate the narrowed aortic valve by inflating the balloon.

<span class="mw-page-title-main">Percutaneous coronary intervention</span> Medical techniques used to manage coronary occlusion

Percutaneous coronary intervention (PCI) is a minimally invasive non-surgical procedure used to treat narrowing of the coronary arteries of the heart found in coronary artery disease. The procedure is used to place and deploy coronary stents, a permanent wire-meshed tube, to open narrowed coronary arteries. PCI is considered 'non-surgical' as it uses a small hole in a peripheral artery (leg/arm) to gain access to the arterial system, an equivalent surgical procedure would involve the opening of the chest wall to gain access to the heart area. The term 'coronary angioplasty with stent' is synonymous with PCI. The procedure visualises the blood vessels via fluoroscopic imaging and contrast dyes. PCI is performed by an interventional cardiologists in a catheterization laboratory setting.

The history of invasive and interventional cardiology is complex, with multiple groups working independently on similar technologies. Invasive and interventional cardiology is currently closely associated with cardiologists, though the development and most of its early research and procedures were performed by diagnostic and interventional radiologists.

<span class="mw-page-title-main">Intima–media thickness</span>

Intima–media thickness (IMT), also called intimal medial thickness, is a measurement of the thickness of tunica intima and tunica media, the innermost two layers of the wall of an artery. The measurement is usually made by external ultrasound and occasionally by internal, invasive ultrasound catheters. Measurements of the total wall thickness of blood vessels can also be done using other imaging modalities.

The following outline is provided as an overview of and topical guide to cardiology, the branch of medicine dealing with disorders of the human heart. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease and electrophysiology. Physicians who specialize in cardiology are called cardiologists.

Nicholas George Kounis is professor emeritus of cardiology in the University of Patras and scientific cardiology advisor at Saint Andrews State General Hospital Patras and at the Department of cardiology of University of Patras Medical School, Patras, Greece.

Transradial catheterization is an endovascular procedure or catheterization procedure performed to diagnose and treat arterial disease. Endovascular procedure can be performed achieving access in to body’s arterial system from either femoral artery, brachial artery or radial artery in the wrist. The transfemoral approach to perform cardiac catheterization has typically been more prevalent in invasive cardiology. But radial access has gained popularity due to technical advances with catheters and lower complication rates than transfemoral access. The European Society of Cardiology and the American Heart Association both support a radial-first approach in acute coronary syndrome.

<span class="mw-page-title-main">Coronary CT angiography</span> Use of computed tomography angiography to assess the coronary arteries of the heart

Coronary CT angiography is the use of computed tomography (CT) angiography to assess the coronary arteries of the heart. The patient receives an intravenous injection of radiocontrast and then the heart is scanned using a high speed CT scanner, allowing physicians to assess the extent of occlusion in the coronary arteries, usually in order to diagnose coronary artery disease.

The Ikaria Study is a small-scale survey by the University of Athens School of Medicine of the diet and lifestyle of Greek people over age 80 on the island of Ikaria. The study found that the Ikarian diet includes olive oil, red wine, fish, coffee, herbal tea, honey, potatoes, garbanzo beans, black-eyed peas, lentils, and a limited amount of meat, sugar and dairy products, except goat milk.

Srihari S. Naidu is an American physician and Professor of Medicine at New York Medical College who is known for his work on hypertrophic cardiomyopathy including the procedure known as alcohol septal ablation, and for helping to construct the universal diagnostic criteria for cardiogenic shock.

Alain Cribier, FACC, FESC was a French interventional cardiologist, Professor of Medicine and Director of Cardiology at the University of Rouen's Charles Nicolle Hospital. Alain Cribier was best known for performing the world's first transcatheter aortic valve implantation in 2002, first transcatheter mitral commissurotomy in 1995, and first balloon aortic valvuloplasty in 1986.

Sanjiv M. Narayan is a British-born American physician, biomedical engineer, and academic researcher. He is a Professor of Medicine at Stanford University. Narayan's work is focused on treating patients with heart rhythm disorders, particularly those with atrial fibrillation. His research applies bioengineering and computational methods to develop improved diagnostic tools and therapy.

<span class="mw-page-title-main">Günter Breithardt</span> German physician, cardiologist and university professor

Günter Breithardt is a German physician, cardiologist and emeritus university professor. He is known for his research in the field of rhythmology, especially the diagnosis and pharmacological and non-pharmacological therapy of cardiac arrhythmias and acute cardiac death, in particular the identification of arrhythmia-triggering gene mutations. For 21 years he headed the Medical Clinic and Polyclinic C at Münster University Hospital. A number of his academic students hold university management and chief physician positions.

References

  1. Kapoor, Rohit; Sachdeva, Soumya; Zacks, Jerome S. (January 2015). "An Analysis of Global Research Trends in Cardiology Over the Last two Decades". Journal of Clinical and Diagnostic Research. 9 (1): OC06–09. doi:10.7860/JCDR/2015/11223.5453. ISSN   2249-782X. PMC   4347106 . PMID   25738015.
  2. "First Cardiology Department, University of Athens Medical School". Archived from the original on 2014-07-14. Retrieved 2014-04-26.
  3. 1 2 3 "Clinical Cardiology Journal, Profiles in Cardiology" (PDF). Archived from the original (PDF) on 2014-07-14. Retrieved 2014-06-19.
  4. "Hellenic Heart Foundation Board members (greek page)". Archived from the original on 2016-10-17. Retrieved 2014-04-26.
  5. "Christodoulos Stefanadis profile on Emory University Online Directory, Department of Cardiology". Archived from the original on 2016-03-04. Retrieved 2015-03-06.
  6. "Christodoulos Stefanadis Profile on Yale University". Archived from the original on 2015-03-09. Retrieved 2015-03-05.
  7. "Editorial on Hellenic Journal of Cardiology: Renal Denervation in Resistant Hypertension: Radiofrequency Ablation and Chemical Denervation" (PDF). Archived from the original (PDF) on 2016-03-04. Retrieved 2014-04-26.
  8. "Scopus Author Search (PubMed)".
  9. "Google Scholar Stefanadis Christodoulos".
  10. "Hellenic Journal of Cardiology Editorial Committee". Archived from the original on 2014-09-21. Retrieved 2014-04-26.
  11. Kapoor, Rohit; Sachdeva, Soumya; Zacks, Jerome S (January 2015). "An Analysis of Global Research Trends in Cardiology Over the Last two Decades". Journal of Clinical and Diagnostic Research. 9 (1): OC06–OC09. doi:10.7860/JCDR/2015/11223.5453. ISSN   2249-782X. PMC   4347106 . PMID   25738015.
  12. "JACC award for Christodoulos I Stefanadis". Archived from the original on 2016-03-04. Retrieved 2014-04-26.
  13. "Simon Dack award for Christodoulos Stefanadis". Archived from the original on 2016-03-04. Retrieved 2014-04-26.