The German Commission E is a scientific advisory board of the Federal Institute for Drugs and Medical Devices formed in 1978. The commission gives scientific expertise for the approval of substances and products previously used in traditional, folk and herbal medicine.
The commission became known beyond Germany in the 1990s for compiling and publishing 380 monographs evaluating the safety and efficacy of herbs for licensed medical prescribing in Germany. The monographs were published between 1984 and 1994 in the Bundesanzeiger ; they have not been updated since then but are still considered valid. A summary of the publications is available on the website of the commission; unofficial copies of the monographs are available at the Heilpflanzen-Welt Bibliothek. [1] The monographs are a collection of official documents compiled over nearly two decades by a committee composed of twenty four scientific experts that was set up in 1978 to evaluate the safety and efficacy of herbal medicines by reviewing the extant literature.
There is an English translation [2] by the American Botanical Council.
The Commission E monographs were imported into the United States with considerable fanfare in 1998 by The American Botanical Council. They were unequivocally endorsed in a foreword by Varro Eugene Tyler, a professor of pharmacognosy at Purdue University. Tyler states in his foreword that "...safety data were reviewed by the Commissioners according to a "doctrine of absolute proof" and efficacy according to a "doctrine of reasonable certainty."
"Certainly worth studying, the Commission E monographs detail which herbs are approved or disapproved, along with their uses, dosages, contraindications, adverse effects, drug interactions, and pharmacologic actions. The therapeutic, taxonomic, and chemical indexes are helpful, as is the glossary." - Journal of the American Medical Association, 1999 [3]
The 1998 book mentioned 10 but omitted 11 possible fatal reactions to the medicines described. [3]
"All [of the monographs] lack literature references. . .." [3]
One critic of Commission E is Jonathan Treasure, a UK-licensed medical herbalist [4] and author of numerous herbalism monographs. [5]
Treasure's lengthy review [6] (31 K) claims that "The failure to include verifiable scientific primary sources necessarily places the entire Commission E Monograph corpus irredeemably outside the most elementary accepted standards of academic requirements for rigorous scientific publications."
Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Unlike modern medicine, which employs the scientific method to test plausible therapies by way of responsible and ethical clinical trials, producing repeatable evidence of either effect or of no effect, alternative therapies reside outside of medical science and do not originate from using the scientific method, but instead rely on testimonials, anecdotes, religion, tradition, superstition, belief in supernatural "energies", pseudoscience, errors in reasoning, propaganda, fraud, or other unscientific sources. Frequently used terms for relevant practices are New Age medicine, pseudo-medicine, unorthodox medicine, holistic medicine, fringe medicine, and unconventional medicine, with little distinction from quackery.
A dietary supplement is a manufactured product intended to supplement one's diet by taking a pill, capsule, tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources or that are synthetic in order to increase the quantity of their consumption. The class of nutrient compounds includes vitamins, minerals, fiber, fatty acids, and amino acids. Dietary supplements can also contain substances that have not been confirmed as being essential to life, but are marketed as having a beneficial biological effect, such as plant pigments or polyphenols. Animals can also be a source of supplement ingredients, such as collagen from chickens or fish for example. These are also sold individually and in combination, and may be combined with nutrient ingredients. The European Commission has also established harmonized rules to help insure that food supplements are safe and appropriately labeled.
Echinacea is a genus of herbaceous flowering plants in the daisy family. It has ten species, which are commonly called coneflowers. They are found only in eastern and central North America, where they grow in moist to dry prairies and open wooded areas. They have large, showy heads of composite flowers, blooming in summer. The generic name is derived from the Greek word ἐχῖνος, meaning "sea urchin", due to the spiny central disk. These flowering plants and their parts have different uses. Some species are cultivated in gardens for their showy flowers. Two of the species, E. tennesseensis and E. laevigata, are listed in the United States as endangered species.
Chinese herbology is the theory of traditional Chinese herbal therapy, which accounts for the majority of treatments in traditional Chinese medicine (TCM). A Nature editorial described TCM as "fraught with pseudoscience", and said that the most obvious reason why it has not delivered many cures is that the majority of its treatments have no logical mechanism of action.
Herbal medicine is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. With worldwide research into pharmacology, some herbal medicines have been translated into modern remedies, such as the anti-malarial group of drugs called artemisinin isolated from Artemisia annua, a herb that was known in Chinese medicine to treat fever. There is limited scientific evidence for the safety and efficacy of many plants used in 21st century herbalism, which generally does not provide standards for purity or dosage. The scope of herbal medicine sometimes include fungal and bee products, as well as minerals, shells and certain animal parts.
A herbal is a book containing the names and descriptions of plants, usually with information on their medicinal, tonic, culinary, toxic, hallucinatory, aromatic, or magical powers, and the legends associated with them. A herbal may also classify the plants it describes, may give recipes for herbal extracts, tinctures, or potions, and sometimes include mineral and animal medicaments in addition to those obtained from plants. Herbals were often illustrated to assist plant identification.
Medicinal plants, also called medicinal herbs, have been discovered and used in traditional medicine practices since prehistoric times. Plants synthesize hundreds of chemical compounds for various functions, including defense and protection against insects, fungi, diseases, and herbivorous mammals.
The European Medicines Agency (EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of pharmaceutical products. Prior to 2004, it was known as the European Agency for the Evaluation of Medicinal Products or European Medicines Evaluation Agency (EMEA).
Kampo or Kanpō medicine, often known simply as Kanpō, is the study of traditional Chinese medicine in Japan following its introduction, beginning in the 7th century. It was adapted and modified to suit Japanese culture and traditions. Traditional Japanese medicine uses most of the Chinese methods, including acupuncture, moxibustion, traditional Chinese herbology, and traditional food therapy.
Natural skin care uses topical creams and lotions made of ingredients available in nature. Much of the recent literature reviews plant-derived ingredients, which may include herbs, roots, flowers and essential oils, but natural substances in skin care products include animal-derived products such as beeswax, and minerals. These substances may be combined with various carrier agents, preservatives, surfactants, humectants and emulsifiers.
In 1998, the Swiss government began a comprehensive Program for Evaluating Complementary Medicine to study the role and effectiveness of complementary medicine, which was playing an ever-increasing role in the Swiss medical system.
Andrographis paniculata, commonly known as creat or green chiretta, is an annual herbaceous plant in the family Acanthaceae, native to India and Sri Lanka.
The European Directorate for the Quality of Medicines & HealthCare (EDQM) is a Directorate of the Council of Europe that traces its origins and statutes to the Convention on the Elaboration of a European Pharmacopoeia.
Iberogast, also known as STW5, is a liquid formulation of nine herbs used for functional dyspepsia and irritable bowel syndrome. A proprietary blend, it was developed in Germany in 1961 and is available in other countries. Named after the genus (Iberis) of one of its ingredients, it is also claimed to possess anti-inflammatory, antioxidative and free radical-inhibiting properties as well as the ability to reduce gastric acid secretion.
Varro Eugene Tyler, of Auburn, Nebraska, was an American professor of pharmacognosy and philatelist who specialized in the study of forged postage stamps and the forgers who created them.
Because of the uncertain nature of various alternative therapies and the wide variety of claims different practitioners make, alternative medicine has been a source of vigorous debate, even over the definition of "alternative medicine". Dietary supplements, their ingredients, safety, and claims, are a continual source of controversy. In some cases, political issues, mainstream medicine and alternative medicine all collide, such as in cases where synthetic drugs are legal but the herbal sources of the same active chemical are banned.
Pulok Kumar Mukherjee is an Indian scientist working as the Director of Institute of Bioresources and Sustainable Development, an autonomous Institute under Department of Biotechnology, Govt. of India, Imphal, Manipur, India; as well as an Associate Editor of the Phytomedicine Plus; Consulting Editor of the Pharmacological Research published by Elsevier. He is the Professor of Pharmaceutical technology at the Jadavpur University and former Director of the School of Natural Product Studies, Jadavpur University, Kolkata, India.
The European Scientific Cooperative on Phytotherapy (ESCOP) was founded in 1989 as an umbrella organisation, representing national European phytotherapy associations. Associations in non-EU states can also be members of ESCOP.