External links
- Crislyn D'Souza-Schorey publications indexed by Google Scholar
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Crislyn D'Souza-Schorey | |
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| Education | University of Texas Health Science Center at San Antonio (PhD, 1992) |
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| Institutions | University of Notre Dame |
Crislyn D'Souza-Schorey is an American-Indian biologist. She is the Morris Pollard Professor and former Department Chair of Biological Sciences at the University of Notre Dame. D'Souza-Schorey researches how membrane trafficking impacts cell motility under normal conditions and in disease states.
D'Souza-Schorey was born and raised in Bombay,India. She completed her bachelor's degree in India at the age of 19 and remained there for her Master's degree. [1] D'Souza-Schorey then moved to the United States where she completed her PhD at the University of Texas Health Science Center at San Antonio in 1992. [2]
Following her PhD,D'Souza-Schorey accepted a postdoctoral fellowship at Washington University School of Medicine. In this role,she began researching therapeutics and diagnostics tools to cure cancer,specifically ARF6. [1] Her research led to the discovery that ARF6 played a role in endosomal membrane trafficking and also governed structural organization at the cell surface. [3]
Following her postdoctoral fellowship,D'Souza-Schorey joined the University of Notre Dame faculty as the Walther Cancer Institute Junior Chair in 1998. [4] Upon starting her own laboratory,she found that ARF6 regulated cell-cell contact. [3] D'Souza-Schorey then began looking into how epithelial cells developed by examining how the protein affected and altered tumor cells. [5] [6]
In 2009,she published a paper which identified a unique population of microvesicles that are enriched in proteases-mediators of tissue degradation. The release of these microvesicles provides a mechanism of tissue breakdown and remodeling at distant sites. [7] As a result of her academic accomplishments,D'Souza-Schorey was elected a Fellow of the American Association for the Advancement of Science in 2012. [8]
In 2014,D'Souza-Schorey became the first woman to be appointed the Department Chair of Biological Sciences at Notre Dame. [9] [10] While serving in this role,she received a patent for a method for detecting invasive microvesicles derived from tumor cells. [11] In 2020,D'Souza-Schorey was recognized with the school's Faculty Award for her "outstanding service to the University such as through leadership activities,mentoring faculty colleagues,or exemplary dedication to students." [12] Later that year,she stepped down as department chair and was replaced by Jason Rohr. [13] In 2022,D'Souza-Schorey was named co-editor-in-chief of the Federation of American Societies for Experimental Biology BioAdvances journal. [14]
D'Souza-Schorey is married to biologist Jeffrey Schorey and they have one son together. [9]
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