Cuterebriasis

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Cuterebriasis is a parasitic disease affecting rodents, lagomorphs (hares, rabbits, pikas), felines, and canines. The etiologic agent is the larval development of botflies within the Cuterebra or Trypoderma genera, which occurs obligatorily in rodents and lagomorphs, respectively. Felines and canines serve as accidental hosts, but research suggests only by Trypoderma spp. Entrance into the body by first-instar larvae occurs via mucous membranes of natural orifices or open wounds as opposed to direct dermic penetration.

Contents

Clinical signs

In rabbits, hares, and lagomorphs, clinical signs usually do not appear. [1] Subcutaneous cysts, warbles, may present upon larval deposition out of the body at maturation. Three forms in which cuterebriasis may present in canines and felines: [1]

Diagnosis

Definitive diagnosis can only occur with positive identification of the larvae. This involves radiologic imaging (preferably MRI, which can reveal larval migration tracks and in some cases the larvae themselves), as well as surgical exploration during which larvae can be removed and examined for identification. [1] Identification of exact species is often impossible, as the instars of the various Cuterebra and Trychoderma spp. exhibit significant resemblance, but identification as a Cuterebra botfly is sufficient for diagnosis as cuterebriasis. Typically, a third larval-instar is found and identifiable by its dark, thick, heavily spined body. [3]

Treatment

Subcutaneous cysts may be surgically opened to remove less-mature bots. If matured, cysts may be opened and Cuterebra may be removed using mosquito forceps. Covering the pore in petroleum jelly may aid in removal. [3] If larvae are discovered within body tissues, rather than subcutaneously, surgical removal is the only means of treatment. Ivermectin may be administered with corticosteroids to halt larval migration in cats presenting with respiratory cuterebriasis, [1] but this is not approved for use in cats. [3] A cure for cerebrospinal cuterebriasis has not been reported.

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References

  1. 1 2 3 4 5 "Cuterebriasis". Companion Animal Parasite Council. June 2012.
  2. 1 2 3 James, Fiona M. K.; Poma, Roberto (2010). "Neurological Manifestations of Feline Cuterebriasis". The Canadian Veterinary Journal. 51 (2): 213–15. PMC   2808293 . PMID   20436872., p. 213.
  3. 1 2 3 4 Moriello, Karen A. (2013). "Cuterebra Infestation in Small Animals". The Merck Veterinary Manual.

Further reading