Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash. Recovery generally takes two to seven days. In a small proportion of cases, the disease develops into a more severe dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where dangerously low blood pressure occurs.
This is a timeline of the development of prophylactic human vaccines. Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market. Although vaccines exist for the diseases listed below, only smallpox has been eliminated worldwide. The other vaccine-preventable illnesses continue to cause millions of deaths each year. Currently, polio and measles are the targets of active worldwide eradication campaigns.
Arbovirus is an informal name for any virus that is transmitted by arthropod vectors. The term arbovirus is a portmanteau word. Tibovirus is sometimes used to more specifically describe viruses transmitted by ticks, a superorder within the arthropods. Arboviruses can affect both animals and plants. In humans, symptoms of arbovirus infection generally occur 3–15 days after exposure to the virus and last three or four days. The most common clinical features of infection are fever, headache, and malaise, but encephalitis and viral hemorrhagic fever may also occur.
Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Four serotypes of the virus have been found, a reported fifth has yet to be confirmed, all of which can cause the full spectrum of disease. Nevertheless, scientists' understanding of dengue virus may be simplistic as, rather than distinct antigenic groups, a continuum appears to exist. This same study identified 47 strains of dengue virus. Additionally, coinfection with and lack of rapid tests for zika virus and chikungunya complicate matters in real-world infections.
Viral hemorrhagic fevers (VHFs) are a diverse group of animal and human illnesses in which fever and hemorrhage are caused by a viral infection. VHFs may be caused by five distinct families of RNA viruses: the families Filoviridae, Flaviviridae, Rhabdoviridae, and several member families of the Bunyavirales order such as Arenaviridae, and Hantaviridae. All types of VHF are characterized by fever and bleeding disorders and all can progress to high fever, shock and death in many cases. Some of the VHF agents cause relatively mild illnesses, such as the Scandinavian nephropathia epidemica, while others, such as Ebola virus, can cause severe, life-threatening disease.
Nesiritide, sold under the brand name Natrecor, is the recombinant form of the 32 amino acid human B-type natriuretic peptide, which is normally produced by the ventricular myocardium. Nesiritide works to facilitate cardiovascular fluid homeostasis through counterregulation of the renin–angiotensin–aldosterone system, stimulating cyclic guanosine monophosphate, leading to smooth muscle cell relaxation.
The Denmark women's national handball team is the national team of Denmark. It is governed by the Dansk Håndbold Forbund (DHF).
Singapore is one of the wealthiest countries in the world, with a gross domestic product (GDP) per capita of more than $57,000. Life expectancy at birth is 82.3 and infant mortality is 2.7 per 1000 live births. The population is ageing and by 2030, 20% will be over 65. However it is estimated that about 85% of those over 65 are healthy and reasonably active. Singapore has a universal health care system.
GOG is a handball club based in the small town of Gudme on Funen, Denmark. The club is one of the most successful in the history of Danish handball having won the Danish Handball Championship 8 times and the Danish Handball Cup a record 10 times. Currently GOG competes in the men's Danish Handball League.
Niklas Landin Jacobsen is a Danish handballer for THW Kiel and the Denmark national team.
A circulatory collapse is defined as a general or specific failure of the circulation, either cardiac or peripheral in nature. Although the mechanisms, causes and clinical syndromes are different, the pathogenesis is the same—the circulatory system fails to maintain the supply of oxygen and other nutrients to the tissues and to remove the carbon dioxide and other metabolites from them. The failure may be hypovolemic or distributive.
The 2009 Bolivian dengue fever epidemic was an epidemic of dengue fever which struck Bolivia in early 2009, escalating into a national emergency by February. The BBC described it as the worst outbreak of dengue fever in the country's history. At least 18 people died and 31,000 were infected by the mosquito-transmitted arbovirus.
As of 2010 dengue fever is believed to infect 50 to 100 million people worldwide a year with 1/2 million life-threatening infections. It dramatically increased in frequency between 1960 and 2010, by 30 fold. This increase is believed to be due to a combination of urbanization, population growth, increased international travel, and global warming. The geographical distribution is around the equator with 70% of the total 2.5 billion people living in endemic areas from Asia and the Pacific. Many of the infected people during outbreaks are not virally tested, therefore their infections may also be due to chikungunya, a coinfection of both, or even other similar viruses.
Anders Eggert Magnussen is a Danish handball coach and former player. He has previously played in Denmark for GOG and Skjern Håndbold, and german side SG Flensburg-Handewitt. He was part of SG Flensburg-Handewitt team that won the 2013–14 EHF Champions League trophy. In his 11 years with SG Flensburg-Handewitt he played in 461 matches and scored 2531 times.
Morten Toft Olsen is a Danish handballer for GOG Håndbold.
Umesh Chandra Chaturvedi was an Indian virologist, immunologist, medical microbiologist, CSIR Emeritus Scientist and a former chairman of the Bharat Immunologicals and Biologicals Corporation. The founder head of the department of microbiology at King George's Medical University, he is known for his studies on Dengue virus infection. Chaturvedi is an elected fellow of all the three major Indian science academies viz. Indian Academy of Sciences, National Academy of Sciences, India and the Indian National Science Academy as well as the Royal College of Pathologists and National Academy of Medical Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1981.
The Danish Women's Handball Cup, known as the Santander Cup for sponsorship reasons, is the main domestic cup tournament for Danish women's handball clubs, which is partially organised and supervised by the Danish Handball Federation. The competition has been played annually since 1964.
The 2018 Danish Handball Cup, known as Santander Cup 2018 for sponsorship reasons, is the 55th edition of the national women's handball cup tournament. Team Esbjerg are the defending champions.
