Daniel Brat

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Daniel Jay Brat is an American neuropathologist and brain tumor investigator. He is the Magerstadt Professor and Chair of Pathology at Northwestern University Feinberg School of Medicine and Northwestern Memorial Healthcare.

Contents

Education

Brat earned his medical degree from the Mayo Medical School and doctoral degree from the Mayo Graduate School in 1994. He subsequently completed his residency in anatomic pathology and a fellowship in neuropathology at Johns Hopkins Hospital. [1]

Career

In 1999, Brat joined the faculty of Pathology and Laboratory Medicine at Emory University. [2] The next year, he became involved with the World Health Organization (WHO) Classification of Brain Tumors, and his research with the TCGA on diffuse gliomas has helped develop a new molecular classification that is used by the WHO and the subject of CAP guideline development. [3] [4] From 2009 until 2011, Brat served as vice-chair of the College of American Pathologists (CAP) Neuropathology Committee, before being elected chair from 2012 until 2015. [5] While sitting as chair, Brat was elected to the American Society for Clinical Investigation. [6]

In his final year as chair, Brat was appointed chair of the Pathology and Biospecimen Committee as he led a clinical trial that attempted to find effective responses to the brain tumour glioblastoma. [7] By 2016, Brat was honoured with the CAP lifetime achievement award. [8] He also co-authored "Practical Surgical Neuropathology: A Diagnostic Approach" with A. Perry in 2011. [9]

Brat stayed at Emory for 17 years before accepting a position as Magerstadt Professor and Chair of Pathology at the Northwestern University Feinberg School of Medicine and Pathologist-in-Chief of Northwestern Memorial Hospital. [1] In 2018, Brat and Eileen Bigio were elected president and vice president of the American Association of Neuropathologists. [10]

Related Research Articles

<span class="mw-page-title-main">Pathology</span> Study of the causes and effects of disease or injury, and how they arise

Pathology is the study of the causes and effects of disease or injury. The word pathology also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue and human cell samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases, and the affix pathy is sometimes used to indicate a state of disease in cases of both physical ailment and psychological conditions. A physician practicing pathology is called a pathologist.

<span class="mw-page-title-main">Anatomical pathology</span> Medical specialty

Anatomical pathology (Commonwealth) or Anatomic pathology (U.S.) is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues. Over the last century, surgical pathology has evolved tremendously: from historical examination of whole bodies (autopsy) to a more modernized practice, centered on the diagnosis and prognosis of cancer to guide treatment decision-making in oncology. Its modern founder was the Italian scientist Giovan Battista Morgagni from Forlì.

<span class="mw-page-title-main">Neuropathology</span> Study of disease of nervous system tissue

Neuropathology is the study of disease of nervous system tissue, usually in the form of either small surgical biopsies or whole-body autopsies. Neuropathologists usually work in a department of anatomic pathology, but work closely with the clinical disciplines of neurology, and neurosurgery, which often depend on neuropathology for a diagnosis. Neuropathology also relates to forensic pathology because brain disease or brain injury can be related to cause of death. Neuropathology should not be confused with neuropathy, which refers to disorders of the nerves themselves rather than the tissues. In neuropathology, the branches of the specializations of nervous system as well as the tissues come together into one field of study.

<span class="mw-page-title-main">Feinberg School of Medicine</span> Medical school of Northwestern University

Northwestern University Feinberg School of Medicine is the medical school of Northwestern University and is located in the Streeterville neighborhood of Chicago, Illinois. Founded in 1859, Feinberg offers a full-time Doctor of Medicine degree program, multiple joint degree programs, graduate medical education, and continuing medical education.

James Watson Kernohan, M.D. (1896–1981) was an Irish-American pathologist born October 1, 1896 in County Antrim, Ireland. He studied medicine at Queen's University Belfast, and in 1922 he emigrated to the United States and subsequently worked as a pathologist at the Mayo Clinic in Rochester, Minnesota. Kernohan retired from active medical practice in 1962 and died May 5, 1981.

<span class="mw-page-title-main">Myrtelle Canavan</span> American physician (1879-1953)

Myrtelle May Moore Canavan was an American physician and medical researcher. She was one of the first female pathologists and is best known for publishing a description of Canavan disease in 1931.

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Zeynel A. Karcioglu is a medical and surgical practitioner, researcher and medical educator. He is a diplomate of the American Board of Ophthalmology, specializing in Ophthalmic Oncology and Pathology particularly in areas of retinoblastoma, external eye tumors, and primary and metastatic orbital neoplasms. Karcioglu is also residency and fellowship trained in Anatomic Pathology and Neuropathology and certified by the American Board of Pathology.

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<i>Journal of Clinical Pathology</i> Academic journal

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Sharon Ann Whelan Weiss is an American pathologist who is best known for her contribution to the subspecialty of soft tissue pathology. She is the main author of Soft Tissue Tumors, one of the most widely used textbooks in the field of sarcoma and soft tissue pathology. She is also well known for her seminal descriptions of multiple soft tissue tumors, such as epithelioid hemangioendothelioma and pleomorphic hyalinizing angiectatic tumor of soft parts among others. She has also mentored and trained other well-known soft tissue pathologists.

<span class="mw-page-title-main">Richard Lindenberg</span>

Richard Lindenberg (1911-1992) was a physician and pathologist, a Luftwaffe Captain during World War II, later Chief Neuropathologist of the State of Maryland. He testified before the Rockefeller Commission on the death of President John F. Kennedy.

<span class="mw-page-title-main">Joseph Godwin Greenfield</span> Scottish neuropathologist

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Nelson M. Oyesiku is a Nigerian-born professor of neurosurgery and Endocrinology. Currently, he is the chair of the department of Neurological Surgery and Professor of Medicine (Endocrinology) at the University of North Carolina, Chapel Hill, USA. Previously, he served as the director of the Inaugural Daniel Louis Barrow Chair in Neurosurgery, and Vice-Chairman, Department of Neurological Surgery, and Director of the Neurosurgical Residency Program at the Emory University School of Medicine. He was also the Director of Laboratory and Molecular Neurosurgery and Biotechnology at Emory University School of Medicine.

Valerie A. Fitzhugh is an American pathologist and Associate Professor of Pathology, Immunology, and Laboratory Medicine at Rutgers New Jersey Medical School as well as an Associate Professor of Pathology and Laboratory Medicine at Rutgers Robert Wood Johnson Medical School. She is the Chair of the Department of Pathology, Immunology, and Laboratory Medicine at Rutgers and the Chair at Rutgers Robert Wood Johnson Medical School as well. Fitzhugh specializes in bone and soft tissue pathology and cytopathology and has made the Pathology Power List by The Pathologist Magazine in 2016, 2018, and 2019. She is involved in educating pathology residents and she actively uses social media as a platform for education and for improving diversity in pathology and she also studies how effective social media is at enhancing accurate communication of science and medicine.

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References

  1. 1 2 Williams, Anna (June 2, 2017). "Distinguished Neuropathologist Named Chair of Pathology". news.feinberg.northwestern.edu. Retrieved November 28, 2019.
  2. "Daniel J Brat, MD, PhD". feinberg.northwestern.edu. Retrieved November 28, 2019.
  3. Dunne, Nora. "Precision Pathologist". magazine.nm.org. Retrieved November 28, 2019.
  4. "2019 Board of Directors Election Ballot". uscap.org. Retrieved November 28, 2019.
  5. "CAP16: All-star team presented with CAP and Foundation awards". captodayonline.com. October 2016. Retrieved November 28, 2019.
  6. "Emory faculty members join prestigious ASCI". news.emory.edu. April 24, 2014. Retrieved November 28, 2019.
  7. "Brat helps lead new global brain cancer study". winshipcancer.emory.edu. November 12, 2015. Retrieved November 28, 2019.
  8. "College of American Pathologists Honors Brat". winshipcancer.emory.edu. September 26, 2016. Retrieved November 25, 2019.
  9. Coons, Stephen W. (January 2011). "Practical Surgical Neuropathology: A Diagnostic Approach Book Review". Journal of Neuropathology & Experimental Neurology. 70 (1): 95. doi: 10.1097/NEN.0b013e318202d6f0 .
  10. Doss, Will (July 13, 2018). "Feinberg Faculty to Lead Neuropathology Society". news.feinberg.northwestern.edu. Retrieved November 28, 2019.