Database of protein conformational diversity

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PCDB
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Description Protein conformational diversity.
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Research center Universidad Nacional de Quilmes
LaboratoryCentro de Estudios e Investigaciones
AuthorsEzequiel I Juritz
Primary citationJuritz & al. (2011) [1]
Release date2010
Access
Website http://www.pcdb.unq.edu.ar

The Database of protein conformational diversity (PCDB) is a database of diversity of protein tertiary structures within protein domains as determined by X-ray crystallography. [1] [2] Proteins are inherently flexible and this database collects information on this subject for use in molecular research. It uses the CATH database as a source of structures for each protein and reports the range of differences in the structures based on their superposition and reports a maximum RMSD. The interface for the database allows researchers to find proteins with a range of conformational flexibility allowing them to find highly flexible proteins for example. The database is run and maintained by a group of researchers based at the Universidad Nacional de Quilmes in Argentina.[ citation needed ]

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References

  1. 1 2 Juritz EI, Alberti SF, Parisi GD (January 2011). "PCDB: a database of protein conformational diversity". Nucleic Acids Res. 39 (Database issue): D475–9. doi:10.1093/nar/gkq1181. PMC   3013735 . PMID   21097895.
  2. Galperin MY, Cochrane GR (January 2011). "The 2011 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection". Nucleic Acids Res. 39 (Database issue): D1–6. doi:10.1093/nar/gkq1243. PMC   3013748 . PMID   21177655.