David Redish

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Aaron David Redish is a Distinguished McKnight University Professor of Neuroscience at the University of Minnesota. [1]

Contents

Education

Redish graduated from Johns Hopkins University in 1991, having completed a double major in Computer Science and Writing Seminars. He then earned a PhD in Computer Science from Carnegie Mellon University, where he was part of the first class of the nascent Center for the Neural Basis of Cognition. After receiving his PhD in 1997, he did postdoctoral work with Carol A. Barnes at the University of Arizona. He joined the Department of Neuroscience at the University of Minnesota as an assistant professor in 2000 and has been there since. [2]

Career and research

Redish is a Distinguished McKnight University Professor of Neuroscience at the University of Minnesota. He was the Director of Graduate Studies for the Department of Neuroscience from 2014 to 2019.

Redish is a published and cited researcher in Computational Neuroscience and Computational Psychiatry, with over 120 publications and over 9,000 citations. [3] His first published papers were computational models of the head direction system in the rodent (see [4] [5] ) which have since been confirmed in both mammals (see [6] ) and drosophila (see [7] ).  Redish then shifted his focus to computational models of rodent navigation and the role of the hippocampus, culminating in a large-scale synthesis which unified the conflicting perspectives on spatial navigation and episodic memory in hippocampus into a single computational model (see [8] ). He studies planning and decision making in rodents, and has argued that this planning system is one of multiple decision-systems. Much of Redish's more recent work has addressed how the computational processes underlying multiple decision-making systems impact fields beyond neuroscience, including economics (see [9] [10] ). Redish is also well known for his work in computational psychiatry, starting from his groundbreaking research in addiction (see [11] [12] [13] ). 

In 2015, Redish organized a Strungmann Forum on Computational Psychiatry with NIH Director Joshua Gordon, bringing together practicing clinicians and computational neuroscientists. [14] He currently co-directs the NeuroPlasticity Research in Support of Mental Health (NeuroPRSMH group, which is known for translational neuroscience and cross-species translation. [15] [16] [17] [18]

Books

David Redish has published several books in his academic field. ISBN   0-7475-3269-9

Awards and honors

2021 Academy of Excellence, University of Minnesota [19]

2014-2015 Hebb Lecture, McGill University [20]

2010-2013 Human Frontiers Science Program Project Award [21]

2003-2005 Alfred P. Sloan Fellow [22]

2002-2004 McKnight Technology Innovation in Neuroscience Award [23]

1998 Distinguished Thesis Award: Computer Science Department, Carnegie Mellon University [24]

Related Research Articles

<span class="mw-page-title-main">Neuroscience</span> Scientific study of the nervous system

Neuroscience is the scientific study of the nervous system, its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences.

<span class="mw-page-title-main">Hippocampus</span> Vertebrate brain region involved in memory consolidation

The hippocampus is a major component of the brain of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus is part of the limbic system, and plays important roles in the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation. The hippocampus is located in the allocortex, with neural projections into the neocortex, in humans as well as other primates. The hippocampus, as the medial pallium, is a structure found in all vertebrates. In humans, it contains two main interlocking parts: the hippocampus proper, and the dentate gyrus.

Computational neuroscience is a branch of neuroscience which employs mathematics, computer science, theoretical analysis and abstractions of the brain to understand the principles that govern the development, structure, physiology and cognitive abilities of the nervous system.

<span class="mw-page-title-main">Dentate gyrus</span> Region of the hippocampus in the brain

The dentate gyrus (DG) is part of the hippocampal formation in the temporal lobe of the brain, which also includes the hippocampus and the subiculum. The dentate gyrus is part of the hippocampal trisynaptic circuit and is thought to contribute to the formation of new episodic memories, the spontaneous exploration of novel environments and other functions.

<span class="mw-page-title-main">Behavioral neuroscience</span> Field of study

Behavioral neuroscience, also known as biological psychology, biopsychology, or psychobiology, is the application of the principles of biology to the study of physiological, genetic, and developmental mechanisms of behavior in humans and other animals.

<span class="mw-page-title-main">Adult neurogenesis</span> Generating of neurons from neural stem cells in adults

Adult neurogenesis is the process in which neurons are generated from neural stem cells in the adult. This process differs from prenatal neurogenesis.

<span class="mw-page-title-main">David S. Touretzky</span>

David S. Touretzky is a research professor in the Computer Science Department and the Center for the Neural Basis of Cognition at Carnegie Mellon University. He received a BA in Computer Science at Rutgers University in 1978, and earned a master's degree and a Ph.D. (1984) in Computer Science at Carnegie Mellon University. Touretzky has worked as an Internet activist in favor of freedom of speech, especially what he perceives as abuse of the legal system by government and private authorities. He is a notable critic of Scientology.

Head direction (HD) cells are neurons found in a number of brain regions that increase their firing rates above baseline levels only when the animal's head points in a specific direction. They have been reported in rats, monkeys, mice, chinchillas and bats, but are thought to be common to all mammals, perhaps all vertebrates and perhaps even some invertebrates, and to underlie the "sense of direction". When the animal's head is facing in the cell's "preferred firing direction" these neurons fire at a steady rate, but firing decreases back to baseline rates as the animal's head turns away from the preferred direction.

<span class="mw-page-title-main">Orbitofrontal cortex</span> Region of the prefrontal cortex of the brain

The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes of the brain which is involved in the cognitive process of decision-making. In non-human primates it consists of the association cortex areas Brodmann area 11, 12 and 13; in humans it consists of Brodmann area 10, 11 and 47.

<span class="mw-page-title-main">Michael Hasselmo</span> American neuroscientist

Michael Hasselmo is an American neuroscientist and professor in the Department of Psychological and Brain Sciences at Boston University. He is the director of the Center for Systems Neuroscience and is editor-in-chief of Hippocampus (journal). Hasselmo studies oscillatory dynamics and neuromodulatory regulation in cortical mechanisms for memory guided behavior and spatial navigation using a combination of neurophysiological and behavioral experiments in conjunction with computational modeling. In addition to his peer-reviewed publications, Hasselmo wrote the book How We Remember: Brain Mechanisms of Episodic Memory.

Pendleton Read Montague, Jr. is an American neuroscientist and popular science author. He is the director of the Human Neuroimaging Lab and Computational Psychiatry Unit at the Fralin Biomedical Research Institute at VTC in Roanoke, Virginia, where he also holds the title of the inaugural Virginia Tech Carilion Vernon Mountcastle Research Professor. Montague is also a professor in the department of physics at Virginia Tech in Blacksburg, Virginia and professor of Psychiatry and Behavioral Medicine at Virginia Tech Carilion School of Medicine.

<span class="mw-page-title-main">Mark S. Gold</span>

Mark S. Gold is an American physician, professor, author, and researcher on the effects of opioids, cocaine, tobacco, and other drugs as well as food on the brain and behavior. He is married to Janice Finn Gold.

<span class="mw-page-title-main">Carol A. Barnes</span> American neuroscientist

Carol A. Barnes is an American neuroscientist who is a Regents' Professor of psychology at the University of Arizona. Since 2006, she has been the Evelyn F. McKnight Chair for Learning and Memory in Aging and is director of the Evelyn F. McKnight Brain Institute. Barnes has been president of the Society for Neuroscience and is a Fellow of the American Association for the Advancement of Science, and foreign member of the Royal Norwegian Society of Sciences and Letters. She was elected to the National Academy of Sciences in 2018.

Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). In short, it is brain growth in relation to its organization. This occurs in all species of animals except the porifera (sponges) and placozoans. Types of NSCs include neuroepithelial cells (NECs), radial glial cells (RGCs), basal progenitors (BPs), intermediate neuronal precursors (INPs), subventricular zone astrocytes, and subgranular zone radial astrocytes, among others.

<span class="mw-page-title-main">Neil Burgess (neuroscientist)</span> British neuroscientist (born 1966)

Neil Burgess is a British neuroscientist. He has been a professor of cognitive neuroscience at University College London since 2004 and a Wellcome Trust Principal Research Fellow since 2011. He has made important contributions to understanding memory and spatial cognition by developing computational models relating behaviour to activity in biological neural networks.

Anne K. Churchland is a neuroscientist at University of California, Los Angeles. Her laboratory studies the function of the posterior parietal cortex in cognitive processes such as decision-making and multisensory integration. One of her discoveries is that individual neurons in rodent posterior parietal cortex can multitask i.e. play a role in multiple behaviors. Another discovery is that rodents are similar to humans in their ability to perform multisensory integration, i.e. to integrate stimuli from two different modalities such as vision and hearing.

<span class="mw-page-title-main">Marisa Roberto</span> American neuroscientist

Marisa Roberto is an Italian-American neuroscientist and professor in the Department of Molecular Medicine and Neuroscience at The Scripps Research Institute in La Jolla, California. Roberto is recognized for her contributions to the understanding of alcohol addiction, specifically for her research on the effects of alcohol and neuromodulators on synaptic transmission in the central amygdala, a critical addiction-related brain region.

<span class="mw-page-title-main">Bita Moghaddam</span> Iranian-American neuroscientist

Bita Moghaddam is an Iranian-American neuroscientist and author. She is currently the Ruth Matarazzo Professor of Behavioral Neuroscience at Oregon Health & Science University. Moghaddam investigates the neuronal processes underlying emotion and cognition as a first step to designing strategies to treat and prevent brain illnesses.

Ilana B. Witten is an American neuroscientist and professor of psychology and neuroscience at Princeton University. Witten studies the mesolimbic pathway, with a focus on the striatal neural circuit mechanisms driving reward learning and decision making.

<span class="mw-page-title-main">Farah Lubin</span> American neuroscientist

Farah D. Lubin is an American neuroscientist and Professor of Neurobiology and Cell, Developmental, and Integrative Biology at the University of Alabama at Birmingham within the Heersink School of Medicine. Lubin is the Principal Investigator of the Lubin Lab which explores the epigenetic mechanisms underlying cognition and how these mechanisms are altered in disease states such as epilepsy and neurodegeneration. Lubin discovered the role of NF-κB in fear memory reconsolidation and also uncovered a novel role for epigenetic regulation of BDNF during long-term memory formation and in epilepsy leading to memory loss. Lubin is a champion for diversity at UAB as the Director of the Roadmap Scholar Program and as a faculty mentor for several institutional and national programs to increase retention of underrepresented minorities in STEM.

References

  1. ↑ "Distinguished McKnight University Professors | Scholars Walk".
  2. ↑ "A. David Redish". Medical School. Retrieved 2023-02-24.
  3. ↑ "Scopus preview - Redish, Aaron David - Author details - Scopus".
  4. ↑ "APA PsycNet". psycnet.apa.org. Retrieved 2023-02-26.
  5. ↑ Redish, A. David; Elga, Adam N.; Touretzky, David S. (November 1996). "A coupled attractor model of the rodent Head Direction system". Network: Computation in Neural Systems. 7 (4): 671–685. doi:10.1088/0954-898X_7_4_004. ISSN   0954-898X.
  6. ↑ Peyrache, Adrien; Lacroix, Marie M.; Petersen, Peter C.; Buzsáki, György (April 2015). "Internally organized mechanisms of the head direction sense". Nature Neuroscience. 18 (4): 569–575. doi:10.1038/nn.3968. ISSN   1546-1726. PMC   4376557 . PMID   25730672.
  7. ↑ Green, Jonathan; Adachi, Atsuko; Shah, Kunal K.; Hirokawa, Jonathan D.; Magani, Pablo S.; Maimon, Gaby (2017-06-01). "A neural circuit architecture for angular integration in Drosophila". Nature. 546 (7656): 101–106. Bibcode:2017Natur.546..101G. doi:10.1038/nature22343. ISSN   1476-4687. PMC   6320684 . PMID   28538731.
  8. ↑ Redish, A. D.; Touretzky, D. S. (1997). "Cognitive maps beyond the hippocampus". Hippocampus. 7 (1): 15–35. doi:10.1002/(SICI)1098-1063(1997)7:1<15::AID-HIPO3>3.0.CO;2-6. ISSN   1050-9631. PMID   9138665. S2CID   18421257.
  9. ↑ van der Meer, Matthijs; Kurth-Nelson, Zeb; Redish, A. David (2012-04-09). "Information Processing in Decision-Making Systems". The Neuroscientist. 18 (4): 342–359. doi:10.1177/1073858411435128. ISSN   1073-8584. PMC   4428660 . PMID   22492194.
  10. ↑ Runge, Carlisle Ford; Johnson, Justin Andrew; Nelson, Erik; Redish, A. David (2022-12-15). "A neuroscience-based analysis of impacts of disaster memory on economic valuation". Journal of Neuroscience, Psychology, and Economics. 16: 24–49. doi:10.1037/npe0000168. ISSN   2151-318X. S2CID   254759324.
  11. ↑ Redish, A. David (2004-12-10). "Addiction as a computational process gone awry". Science. 306 (5703): 1944–1947. Bibcode:2004Sci...306.1944R. doi:10.1126/science.1102384. ISSN   1095-9203. PMID   15591205. S2CID   16503204.
  12. ↑ Redish, A. David; Jensen, Steve; Johnson, Adam; Kurth-Nelson, Zeb (July 2007). "Reconciling reinforcement learning models with behavioral extinction and renewal: implications for addiction, relapse, and problem gambling". Psychological Review. 114 (3): 784–805. doi:10.1037/0033-295X.114.3.784. ISSN   0033-295X. PMID   17638506.
  13. ↑ Redish, A. David; Jensen, Steve; Johnson, Adam (August 2008). "A unified framework for addiction: Vulnerabilities in the decision process". The Behavioral and Brain Sciences. 31 (4): 415–487. doi:10.1017/S0140525X0800472X. ISSN   0140-525X. PMC   3774323 . PMID   18662461.
  14. ↑ "Computational Psychiatry".
  15. ↑ https://neuroprsmh.umn.edu/
  16. ↑ "Meeting of the minds". 15 January 2021.
  17. ↑ "Collaborating to a Successful Grant". 22 June 2021.
  18. ↑ "U Researchers Receive $15M NIMH Grant to Study Psychosis". 19 May 2020.
  19. ↑ "Academy for Excellence in Health Research | Academies for Excellence". academies-excellence.umn.edu. Retrieved 2023-02-24.
  20. ↑ "Hebb Lectures Archive". Department of Psychology. Retrieved 2023-02-24.
  21. ↑ "Deliberative decision-making in rats | Human Frontier Science Program". www.hfsp.org. Retrieved 2023-02-24.
  22. ↑ "Fellows Database". sloan.org. Retrieved 2023-02-24.
  23. ↑ "Awardees". McKnight Foundation. Retrieved 2023-02-24.
  24. ↑ "SCS STUDENT AWARDS". www.scs.cmu.edu. Retrieved 2023-02-24.
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