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Genomic imprinting is an epigenetic phenomenon that causes genes to be expressed or not, depending on whether they are inherited from the mother or the father. Genes can also be partially imprinted. Partial imprinting occurs when alleles from both parents are differently expressed rather than complete expression and complete suppression of one parent's allele. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. In 2014, there were about 150 imprinted genes known in mice and about half that in humans. As of 2019, 260 imprinted genes have been reported in mice and 228 in humans.
Mary Frances Lyon was an English geneticist best known for her discovery of X-chromosome inactivation, an important biological phenomenon.
Rudolf Jaenisch is a Professor of Biology at MIT and a founding member of the Whitehead Institute for Biomedical Research. He is a pioneer of transgenic science, in which an animal’s genetic makeup is altered. Jaenisch has focused on creating genetically modified mice to study cancer and neurological diseases.
Charles David Allis is an American molecular biologist, and is currently the Joy and Jack Fishman Professor and head of the Laboratory of Chromatin Biology and Epigenetics at The Rockefeller University.
The Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany is an interdisciplinary research institute that conducts basic research in modern immunobiology, developmental biology and epigenetics. It was founded in 1961 as the Max Planck Institute of Immunobiology and is one of 86 institutions of the Max Planck Society. Originally named the Max Planck Institute of Immunobiology, it was renamed to its current name in 2010 as it widened its research thrusts to the study of epigenetics.
Rudi Balling is a German geneticist. He is the founding director of the Luxembourg Centre for Systems Biomedicine at the University of Luxembourg (2009-2021) He has served as President of the International Mammalian Genome Society and as co-editor of the Annual Review of Nutrition since 2018. In 2016 Balling received Luxembourg's Ordre de Mérite (Commandeur) from Prime Minister Xavier Bettel.
Sir Adrian Peter Bird, is a British geneticist and Buchanan Professor of Genetics at the University of Edinburgh. Bird has spent much of his academic career in Edinburgh, from receiving his PhD in 1970 to working at the MRC Mammalian Genome Unit and later serving as director of the Wellcome Trust Centre for Cell Biology. His research focuses on understanding DNA methylation and CpG islands, and their role in diseases such as Rett syndrome.
Randy Jirtle is an American biologist noted for his research in epigenetics, the branch of biology that deals with inherited information that does not reside in the nucleotide sequence of DNA. Jirtle retired from Duke University, Durham, NC in 2012. He is Professor of Epigenetics in the Department of Biological Sciences at North Carolina State University, Raleigh, NC, and Senior Visiting Scientist at the McArdle Laboratory of Cancer Research, University of Wisconsin, Madison, WI. Jirtle is noted for his research on genomic imprinting, and for his use of the Agouti mouse model to investigate the effect of environmental agents on the mammalian epigenome and disease susceptibility.
Wolf Reik FRS is a German molecular biologist and a group leader at the Babraham Institute, honorary professor of Epigenetics at the University of Cambridge and associate faculty at the Wellcome Trust Sanger Institute. He was announced as the director of Altos Labs Cambridge Institute when the company launched on 19 January 2022.
Emmanuelle Marie Charpentier is a French professor and researcher in microbiology, genetics, and biochemistry. As of 2015, she has been a director at the Max Planck Institute for Infection Biology in Berlin. In 2018, she founded an independent research institute, the Max Planck Unit for the Science of Pathogens. In 2020, Charpentier and American biochemist Jennifer Doudna of the University of California, Berkeley, were awarded the Nobel Prize in Chemistry "for the development of a method for genome editing". This was the first science Nobel Prize ever won by two women only.
Anne Carla Ferguson-Smith is a mammalian developmental geneticist. She is the Arthur Balfour Professor of Genetics and Pro-Vice Chancellor for Research and International Partnerships at the University of Cambridge. Formerly Head of the Department of Genetics at the University of Cambridge, she is a Fellow of Darwin College, Cambridge and currently President of the Genetics Society.
Thomas Jenuwein is a German scientist working in the fields of epigenetics, chromatin biology, gene regulation and genome function.
Christoph Bock is a German bioinformatician and principal investigator at the Research Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences and a visiting professor at the Medical University of Vienna.
Azim Surani is a Kenyan-British developmental biologist who has been Marshall–Walton Professor at the Wellcome Trust/Cancer Research UK Gurdon Institute at the University of Cambridge since 1992, and Director of Germline and Epigenomics Research since 2013.
Xu Guoliang is a Chinese molecular geneticist. He is a professor at the Shanghai Institute of Biochemistry and Cell Biology and an academician of the Chinese Academy of Sciences.
The Department of Genetics is a department of the University of Cambridge that conducts research and teaching in genetics.
Asifa Akhtar is a Pakistani biologist who has made significant contributions to the field of chromosome regulation. She is Senior Group Leader and Director of the Department of Chromatin Regulation at the Max Planck Institute of Immunobiology and Epigenetics. Akhtar was awarded EMBO membership in 2013. She became the first international and female Vice President of the Max Planck Society's Biology and Medicine Section in July 2020.
Rolf Kemler, is a German molecular biologist who is currently the Emeritus Director at the Max Planck Institute of Immunobiology and Epigenetics. He has contributed significantly to the study of anchoring junctions, specifically the cadherin family of proteins and was the recipient of the 2020 Canada Gairdner International Award for his work in the field.
Marisa Bartolomei is an American cell biologist, the Perelman Professor of Cell and Developmental Biology and Co-Director of the Epigenetics Institute at the Perelman School of Medicine at the University of Pennsylvania. Her research considers epigenetic processes including genomic imprinting. She was elected to the National Academy of Sciences in 2021.
Thomas Boehm is a German immunologist. He is the Director of the Max Planck Institute for Immunobiology and Epigenetics in Freiburg im Breisgau. He has won a variety of prizes for his research work.
References
- 1 2 "Davor Solter receives Gairdner Award 2018". Max Planck Institute of Immunobiology and Epigenetics. March 28, 2018. Retrieved 25 March 2019.
- 1 2 3 "Davor Solter". The Academy of Europe. Retrieved 25 March 2019.
- ↑ "Previous Directors of the Institute". Max Planck Institute of Immunobiology and Epigenetics. Retrieved 25 March 2019.
- ↑ "Gairdner Awards 2018 Laureates | Gairdner Foundation". Gairdner Foundation. Retrieved 2018-09-21.
- ↑ "Past Winners". Brandeis University. Retrieved 25 March 2019.
- ↑ "March of Dimes and Richard B. Johnston, Jr, MD Prize in Developmental Biology awardees" (PDF). March of Dimes. Retrieved 25 March 2019.
