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Human papillomavirus infection is caused by a DNA virus from the Papillomaviridae family. Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. In some cases, an HPV infection persists and results in either warts or precancerous lesions. These lesions, depending on the site affected, increase the risk of cancer of the cervix, vulva, vagina, penis, anus, mouth, tonsils, or throat. Nearly all cervical cancer is due to HPV and two strains – HPV16 and HPV18 – which account for 70% of cases. HPV16 is responsible for almost 90% of HPV-positive oropharyngeal cancers. Between 60% and 90% of the other cancers listed above are also linked to HPV. HPV6 and HPV11 are common causes of genital warts and laryngeal papillomatosis.
The Fred Hutchinson Cancer Center, formerly known as the Fred Hutchinson Cancer Research Center and also known as Fred Hutch or The Hutch, is a cancer research institute established in 1975 in Seattle, Washington.
Linda Brown Buck is an American biologist best known for her work on the olfactory system. She was awarded the 2004 Nobel Prize in Physiology or Medicine, along with Richard Axel, for their work on olfactory receptors. She is currently on the faculty of the Fred Hutchinson Cancer Research Center in Seattle.
Stanley "Stan" Falkow was an American microbiologist and a professor of microbiology at Georgetown University, University of Washington, and Stanford University School of Medicine. Falkow is known as the father of the field of molecular microbial pathogenesis. He formulated molecular Koch's postulates, which have guided the study of the microbial determinants of infectious diseases since the late 1980s. Falkow spent over 50 years uncovering molecular mechanisms of how bacteria cause disease and how to disarm them. Falkow also was one of the first scientists to investigate antimicrobial resistance, and presented his research extensively to scientific, government, and lay audiences explaining the spread of resistance from one organism to another, now known as horizontal gene transfer, and the implications of this phenomenon on our ability to combat infections in the future.
Bettie M. Steinberg holds multiple positions within Northwell Health: Chief Scientific Officer for The Feinstein Institute for Medical Research, Dean of the Elmezzi Graduate School of Molecular Medicine, and Chair of the Department of Molecular Medicine at the Hofstra Northwell School of Medicine in Hempstead, NY.
C. Richard Schlegel is an American scientist and professor. He was the Chair of the Department of Pathology at Georgetown University from 2000-2019 and is now the director of the Center for Cell Reprogramming at Georgetown. Conditionally Reprogrammed Cells (CRC) technology.
The Szent-Györgyi Prize for Progress in Cancer Research, established by National Foundation for Cancer Research (NFCR) and named in honor of Albert Szent-Györgyi, Nobel laureate and co-founder of NFCR, has been awarded annually since 2006 to outstanding researchers whose scientific achievements have expanded the understanding of cancer and whose vision has moved cancer research in new directions. The Szent-Györgyi Prize honors researchers whose discoveries have made possible new approaches to preventing, diagnosing and/or treating cancer. The Prize recipient is honored at a formal dinner and award ceremony and receives a $25,000 cash prize. In addition, the recipient leads the next "Szent-Györgyi Prize Committee" as honorary chairman.
Elaine Ann Ostrander is an American geneticist at the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH) in Bethesda, Maryland. She holds a number of professional academic appointments, currently serving as Distinguished and Senior Investigator and head of the NHGRI Section of Comparative Genomics; and Chief of the Cancer Genetics and Comparative Genomics Branch. She is known for her research on prostate cancer susceptibility in humans and for conducting genetic investigations with the Canis familiaris —the domestic dog— model, which she has used to study disease susceptibility and frequency and other aspects of natural variation across mammals. In 2007, her laboratory showed that much of the variation in body size of domestic dogs is due to sequence changes in a single gene encoding a growth-promoting protein.
Jackson Orem is a physician, medical oncologist and researcher in Uganda. He has served as the director of the Uganda Cancer Institute, since 2004.
Professor Carol L. Prives FRS is the Da Costa Professor of Biological Sciences at Columbia University. She is known for her work in the characterisation of p53, an important tumor suppressor protein frequently mutated in cancer.
Thea D. Tlsty is an American pathologist and professor of pathology at the University of California, San Francisco (UCSF). She is known for her research in cancer biology and her involvement in the discovery of cells that may be at the origin of metaplastic cancer, an invasive form of breast cancer.
Cecilia Moens is a Canadian developmental biologist. Moens is part of the faculty at the Fred Hutchinson Cancer Research Center in Seattle, Washington, where she researches the vertebrate brain using zebrafish as a model organism.
Maura Lianne Gillison is an American medical oncologist and molecular epidemiologist. She is credited as the first investigator to establish a connection between HPV and oral cancer.
Helen Margaret Piwnica-Worms is an American cell-cycle researcher. Since 2013, she has served as vice provost of science at the MD Anderson Cancer Center and professor in MD Anderson's Department of Cancer Biology.
Teresa Shu-Fong Wang is an American biochemist.
W. Kimryn Rathmell is an American physician-scientist whose work focuses on the research and treatment of patients with kidney cancers. She is the Hugh Jackson Morgan Professor and Chair of the Department of Medicine at Vanderbilt University Medical Center (VUMC), and Physician-in-Chief for Vanderbilt University Adult Hospital and Clinics in Nashville, Tennessee.
Amanda Grace Paulovich is an oncologist, and a pioneer in proteomics using multiple reaction monitoring mass spectrometry to study tailored cancer treatment.
Garnet Larae Anderson is an American biostatistician, known for her research on the health risks caused by side effects of postmenopausal hormone therapy, and more generally as one of the leading researchers in the Women's Health Initiative. She is a senior vice president at the Fred Hutchinson Cancer Research Center, where she directs the Public Health Sciences Division and holds the Fred Hutch 40th Anniversary Endowed Chair; she is also an affiliate professor of biostatistics at the University of Washington.
Michelle Adair Ozbun is an American molecular virologist who is the Maralyn S. Budke Endowed Professor in Viral Oncology at the University of New Mexico School of Medicine. Her research considers cancer biology and how human papillomavirus infections cause pathology including their contributions to cancers.
Aimée Rebecca Kreimer is an American cancer epidemiologist who researches the etiology and prevention of human papillomavirus infection (HPV) and cancer prevention. She is a senior investigator in the infections and immunoepidemiology branch at the National Cancer Institute.
References
- 1 2 "Denise Galloway helped pave the way for the HPV vaccine". Puget Sound Business Journal. Retrieved 9 September 2020.
- ↑ "Denise Galloway | University of Washington - Department of Global Health". globalhealth.washington.edu. Retrieved 9 September 2020.
- ↑ "Galloway, Denise". IPVS. Retrieved 9 September 2020.
- 1 2 "Spotlight on Denise Galloway". Fred Hutch. Retrieved 9 September 2020.
- ↑ "Dr. Denise A. Galloway".
- ↑ "Denise A. Galloway". American Academy of Arts & Sciences. Retrieved 9 September 2020.
- ↑ "Denise A. Galloway, PhD". American Association for Cancer Research (AACR). Retrieved 2022-08-10.
