The Labrador Retriever or simply Labrador is a British breed of retriever gun dog. It was developed in the United Kingdom from St. John's water dogs imported from the colony of Newfoundland, and was named after the Labrador region of that colony. It is among the most commonly kept dogs in several countries, particularly in the European world.
Life extension is the concept of extending the human lifespan, either modestly through improvements in medicine or dramatically by increasing the maximum lifespan beyond its generally-settled biological limit of around 125 years. Several researchers in the area, along with "life extensionists", "immortalists", or "longevists", postulate that future breakthroughs in tissue rejuvenation, stem cells, regenerative medicine, molecular repair, gene therapy, pharmaceuticals, and organ replacement will eventually enable humans to have indefinite lifespans through complete rejuvenation to a healthy youthful condition (agerasia). The ethical ramifications, if life extension becomes a possibility, are debated by bioethicists.
Longevity may refer to especially long-lived members of a population, whereas life expectancy is defined statistically as the average number of years remaining at a given age. For example, a population's life expectancy at birth is the same as the average age at death for all people born in the same year.
Maximum life span is a measure of the maximum amount of time one or more members of a population have been observed to survive between birth and death. The term can also denote an estimate of the maximum amount of time that a member of a given species could survive between birth and death, provided circumstances that are optimal to that member's longevity.
The Goldendoodle, also known as a Groodle, is a designer dog created by crossbreeding a Golden Retriever and a Poodle. First widely bred in the 1990s, they are bred in three different sizes—each corresponding to the size of Poodle used as a parent.
A mongrel, mutt, or mixed-breed dog is a dog that does not belong to one officially recognized breed, including those that result from intentional breeding. Although the term mixed-breed dog is sometimes preferred, many mongrels have no known purebred ancestors.
Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumor (PEComa). It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It is a mechanistic target of rapamycin (mTOR) kinase inhibitor that reduces the sensitivity of T cells and B cells to interleukin-2 (IL-2), inhibiting their activity.
The Nova Scotia Duck Tolling Retriever is a medium-sized gundog bred primarily for hunting. It is often referred to as a "toller". It is the smallest of the retrievers, and is often mistaken for a small Golden Retriever. Tollers are intelligent, eager to please, alert, and energetic. The name "toller" is derived from their ability to lure waterfowl within gunshot range. The breed originated in Yarmouth County, Nova Scotia, Canada. The American Kennel Club ranks the toller as the 87th most popular dog breed.
Dog aggression expressed by dogs is considered to be normal behaviour and various types of aggression are influenced by a dog's environment and genetic predisposition. Dogs commonly display possessive aggression when defending resources or themselves.
Progressive retinal atrophy (PRA) is a group of genetic diseases seen in certain breeds of dogs and, more rarely, cats. Similar to retinitis pigmentosa in humans, it is characterized by the bilateral degeneration of the retina, causing progressive vision loss culminating in blindness. The condition in nearly all breeds is inherited as an autosomal recessive trait, with the exception of the Siberian Husky (inherited as an X chromosome linked trait) and the Bullmastiff (inherited as an autosomal dominant trait). There is no treatment.
The dog is a domesticated descendant of the wolf. Also called the domestic dog, it is derived from extinct gray wolves, and the gray wolf is the dog's closest living relative. The dog was the first species to be domesticated by humans. Experts estimate that hunter-gatherers domesticated dogs more than 15,000 years ago, which was before the development of agriculture. Due to their long association with humans, dogs have expanded to a large number of domestic individuals and gained the ability to thrive on a starch-rich diet that would be inadequate for other canids.
Aging in cats is the process by which cats change over the course of their natural lifespans. The average lifespan of a domestic cat may range from 10 to 15 years. As cats senesce, they undergo predictable changes in health and behavior. Dental disease and loss of olfaction are common as cats age, affecting eating habits. Arthritis and sarcopenia are also common in older cats. How a cat's health is affected by aging may be managed through modifications in a cat's diet, accessibility adjustments, and cognitive stimulation.
Aging in dogs varies from breed to breed, and affects the dog's health and physical ability. As with humans, advanced years often bring changes in a dog's ability to hear, see, and move about easily. Skin condition, appetite, and energy levels often degrade with geriatric age. Medical conditions such as cancer, kidney failure, arthritis, dementia, and joint conditions, and other signs of old age may appear.
Cancer is the leading cause of death in dogs. It is estimated that 1 in 3 domestic dogs will develop cancer, which is the same incidence of cancer among humans. Dogs can develop a variety of cancers and most are very similar to those found in humans. Dogs can develop carcinomas of epithelial cells and organs, sarcomas of connective tissues and bones, and lymphomas or leukemias of the circulatory system. Selective breeding of dogs has led certain pure-bred breeds to be at high-risk for specific kinds of cancer.
The Golden Retriever is a Scottish breed of retriever dog of medium size. It is characterised by a gentle and affectionate nature and a striking golden coat. It is commonly kept as a pet and is among the most frequently registered breeds in several Western countries. It is a frequent competitor in dog shows and obedience trials; it is also used as a gun dog and may be trained for use as a guide dog.
The Chihuahua is a Mexican breed of toy dog. It is named for the Mexican state of Chihuahua and is among the smallest of all dog breeds. It is usually kept as a companion animal or for showing.
Project Baseline is a broad effort to map human health led by Verily Life Sciences, Alphabet, Inc.'s health sciences division, and was announced in the Wall Street Journal on July 24, 2014. It begins with the ProjectBaseline Study, which will collect phenotypic health data from approximately 10,000 participants over the course of at least four years. The project employs experts from widely varying fields including science, medicine, user experience and design, engineering and patient advocacy. The project is not the first one to aim to collect data on many individuals for medical purposes, but it aims to collect a much larger amount of data covering a broader array of topics than its predecessors. De-identified Project Baseline study data will be available to qualified researchers for exploratory analysis in the future. Qualified external researchers may apply through applications reviewed by the Proposal Review and Publications Committee and Scientific Executive Committee.
Embark is a canine genomics and biotechnology company based in Boston, Massachusetts. The company offers dog DNA testing services to consumers, breeders, and veterinarians.
Fatal dog attacks are human deaths caused by dogs. The study of fatal dog attacks can lead to prevention techniques which can help to reduce all dog bite injuries, not only fatalities. Dog bites and attacks can result in pain, bruising, wounds, bleeding, soft tissue injury, broken bones, loss of limbs, scalping, disfigurement, life-threatening injuries, and death.
This timeline lists notable events in the history of research into senescence or biological aging, including the research and development of life extension methods, brain aging delay methods and rejuvenation.
