Doug Bremner

Last updated

James Douglas Bremner
Born (1961-06-05) June 5, 1961 (age 61)
Topeka, Kansas, United States
Alma mater University of Puget Sound
Duke University School of Medicine
Occupation
  • Physician
  • researcher
  • writer
Known forThe Goose That Laid the Golden Egg: Accutane, the truth that had to be told

James Douglas Bremner, M.D., (born June 5, 1961) is a physician, researcher, and writer based in Atlanta, Georgia. [1] He has conducted research on posttraumatic stress disorder [2] and the relationship between depression and suicide and the acne drug Accutane (Roaccutane, or isotretinoin). [3]

Contents

Early life and education

Bremner was born in Topeka, Kansas and was raised in Olympia, Washington. [4] [5] He received a B.A. in English literature from the University of Puget Sound, and a medical degree from Duke University School of Medicine. He did residencies in psychiatry and nuclear medicine at the Yale University School of Medicine. [1]

Career

Bremner was an assistant and associate professor of psychiatry and radiology at the Yale University School of Medicine and National Center for PTSD from 1991 to 2000 [2] and Professor of Psychiatry and Radiology, Director of the Emory Clinical Neuroscience Research Unit, [6] at the Emory University School of Medicine in Atlanta, Georgia. He has also served as Director of Mental Health Research at the Atlanta Veterans Administration Medical Center in Decatur, Georgia since 2000. [1]

Bremner's brain imaging studies showed smaller volume of the hippocampus in people with post traumatic stress disorder related to childhood abuse or Vietnam combat; he was the first to publish on the topic of that relationship. [7] These studies and others resulted in him being one of the most highly cited researchers in the field of post traumatic stress disorder. [8]

Bremner's research used PET brain imaging to show a decrease in frontal lobe brain function in acne patients treated with Accutane (isotretinoin). He was an expert witness in litigation related to the relationship between Accutane and suicide and depression, including the case of Charles J. Bishop, [3] which he describes in the narrative non-fiction book The Goose That Laid the Golden Egg.

Bremner's activities as a healthcare consumer advocate and activist include authorship of Before You Take That Pill: Why the Drug Industry May Be Bad for Your Health: Risks and Side Effects You Won't Find on the Label of Commonly Prescribed Drugs, Vitamins, and Supplements. He is frequently quoted by the media in stories related to risks of prescription medications. [9] He has also appeared multiple times on CNN's HLN (TV network) and truTV, discussing medical and mental health aspects of crime stories in the news. [10] He was an active participant in protests related to the Grady Memorial Hospital dialysis crisis of 2009, which contributed to a successful outcome for the affected patients. [11]

Bremner has authored or co-authored over 200 peer reviewed scientific articles, book chapters, and books in the field of PTSD, depression, and drug safety. [12]

He is on the editorial boards of several journals and the Scientific Advisory and Executive Boards of several foundations dedicated to promoting mental health of military personnel deployed to the conflicts in Iraq and Afghanistan. He has received several awards for his work, including the Chaim and Bela Danieli Award for Research and Service in Traumatic Stress from the International Society for Traumatic Stress Studies. [13]

Bremner is also a screenwriter with awards including Quarterfinalist at the 2011 PAGE International Screenwriters Awards. [14]

Publications

Related Research Articles

Post-traumatic stress disorder (PTSD) is a mental and behavioral disorder that can develop because of exposure to a traumatic event, such as sexual assault, warfare, traffic collisions, child abuse, domestic violence, or other threats on a person's life. Symptoms may include disturbing thoughts, feelings, or dreams related to the events, mental or physical distress to trauma-related cues, attempts to avoid trauma-related cues, alterations in the way a person thinks and feels, and an increase in the fight-or-flight response. These symptoms last for more than a month after the event. Young children are less likely to show distress but instead may express their memories through play. A person with PTSD is at a higher risk of suicide and intentional self-harm.

<span class="mw-page-title-main">Isotretinoin</span> Medication primarily used to treat severe acne

Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Roaccutane among others, is a medication primarily used to treat severe acne. It is also used to prevent certain skin cancers, and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body. Its isomer, tretinoin, is also an acne drug.

Psychological trauma, mental trauma or psychotrauma is an emotional response to a distressing event or series of events, such as accidents, rape or natural disasters. Reactions such as psychological shock and psychological denial are typical. Longer-term reactions include unpredictable emotions, flashbacks, difficulties with interpersonal relationships and sometimes physical symptoms including headaches or nausea.

Eye movement desensitization and reprocessing (EMDR) is a form of psychotherapy developed by Francine Shapiro in the 1980s that was originally designed to alleviate the distress associated with traumatic memories such as post-traumatic stress disorder (PTSD). In EMDR, the person being treated recalls distressing experiences whilst doing bilateral stimulation, such as side-to-side eye movement or physical stimulation, such as tapping either side of the body.

Acute stress disorder is a psychological response to a terrifying, traumatic or surprising experience. It may bring about delayed stress reactions if not correctly addressed.

Barbara Rothbaum is a psychologist at Emory University School of Medicine in Atlanta, Georgia. She is a professor in the Psychiatry department and a pioneer in the treatment of anxiety-related disorders. Rothbaum is head of the Trauma and Anxiety Recovery Program (TARP) at Emory as well as the Emory Healthcare Veterans Program. In the mid-1990s she founded a virtual exposure therapy company called Virtually Better, Inc. This company treats patients with anxiety disorders, addictions, pain, and the like using virtual reality instead of the actual place or scenario. It also allows the therapist to control the environment. She also played a key role in the development of the treatment of posttraumatic stress disorder (PTSD).

Complex post-traumatic stress disorder is a psychological disorder that is theorized to develop in response to exposure to a series of traumatic events in a context in which the individual perceives little or no chance of escape, and particularly where the exposure is prolonged or repetitive. It is not yet recognized by the American Psychiatric Association or the DSM-5 as a valid disorder, although was added to the eleventh revision of the International Classification of Diseases (ICD-11). In addition to the symptoms of post-traumatic stress disorder (PTSD), an individual with C-PTSD experiences emotional dysregulation, negative self-beliefs and feelings of shame, guilt or failure regarding the trauma, and interpersonal difficulties. C-PTSD relates to the trauma model of mental disorders and is associated with chronic sexual, psychological, and physical abuse or neglect, or chronic intimate partner violence, bullying, victims of kidnapping and hostage situations, indentured servants, victims of slavery and human trafficking, sweatshop workers, prisoners of war, concentration camp survivors, and prisoners kept in solitary confinement for a long period of time, or defectors from authoritarian religions. Situations involving captivity/entrapment can lead to C-PTSD-like symptoms, which can include prolonged feelings of terror, worthlessness, helplessness, and deformation of one's identity and sense of self.

<span class="mw-page-title-main">Guanfacine</span> Medication

Guanfacine, sold under the brand name Tenex among others, is an oral medication used to treat attention deficit hyperactivity disorder (ADHD) and high blood pressure. Guanfacine is FDA-approved for monotherapy treatment of ADHD as well as being used for augmentation of other treatments, such as stimulants. Guanfacine is also used off-label to treat tic disorders, anxiety disorders and PTSD.

Prolonged exposure therapy (PE) is a form of behavior therapy and cognitive behavioral therapy designed to treat post-traumatic stress disorder. It is characterized by two main treatment procedures – imaginal and in vivo exposures. Imaginal exposure is repeated 'on-purpose' retelling of the trauma memory. In vivo exposure is gradually confronting situations, places, and things that are reminders of the trauma or feel dangerous. Additional procedures include processing of the trauma memory and breathing retraining.

Memory is described by psychology as the ability of an organism to store, retain, and subsequently retrieve information. When an individual experiences a traumatic event, whether physical or psychological, their memory can be affected in many ways. For example, trauma might affect their memory for that event, memory of previous or subsequent events, or thoughts in general. Additionally, It has been observed that memory records from traumatic events are more fragmented and disorganized than recall from non traumatic events. Comparison between narrative of events directly after a traumatic event versus after treatment indicate memories can be processed and organized and that this change is associated with decrease in anxiety related symptoms.

<span class="mw-page-title-main">Dennis S. Charney</span> American medical researcher

Dennis S. Charney is an American biological psychiatrist and researcher, with expertise in the neurobiology and treatment of mood and anxiety disorders. He is the author of Neurobiology of Mental Illness, The Physician's Guide to Depression and Bipolar Disorders and Molecular Biology for the Clinician, as well as the author of over 600 original papers and chapters. In 2022, he was listed #52 on Research.com's "Top Medicine Scientists in the United States," with an h-index of 194 with 146,109 citations across 651 publications. Charney is known for demonstrating that ketamine is effective for treating depression. Ketamine's use as a rapidly-acting anti-depressant is recognized as a breakthrough treatment in mental illness.

<span class="mw-page-title-main">Yuval Neria</span>

Yuval Neria is a Professor of Medical Psychology at the Departments of Psychiatry and Epidemiology at Columbia University Medical Center (CUMC), and Director of Trauma and PTSD Program, and a Research Scientist at the New York State Psychiatric Institute (NYSPI) and Columbia University Department of Psychiatry. He is a recipient of the Medal of Valor, Israel's highest decoration, for his exploits during the 1973 Yom Kippur War.

Daniel S. Schechter is an American psychiatrist known for his clinical work and research on intergenerational transmission or "communication" of violent trauma and related psychopathology involving parents and very young children. His published work in this area following the terrorist attacks on the World Trade Center in New York of September 11, 2001 led to a co-edited book entitled "September 11: Trauma and Human Bonds" (2003) and additional original articles with clinical psychologist Susan Coates that were translated into multiple languages and remain among the first accounts of 9/11 related loss and trauma described by mental health professionals who also experienced the attacks and their aftermath Schechter observed that separation anxiety among infants and young children who had either lost or feared loss of their caregivers triggered posttraumatic stress symptoms in the surviving caregivers. These observations validated his prior work on the adverse impact of family violence on the early parent-child relationship, formative social-emotional development and related attachment disturbances involving mutual dysregulation of emotion and arousal. This body of work on trauma and attachment has been cited by prominent authors in the attachment theory, psychological trauma, developmental psychobiology and neuroscience literatures

Frank Neuner was born 1971. He is professor of Clinical Psychology at Faculty of Psychology and Sports Science, Bielefeld University.

PTSD or post-traumatic stress disorder, is a psychiatric disorder characterised by intrusive thoughts and memories, dreams or flashbacks of the event; avoidance of people, places and activities that remind the individual of the event; ongoing negative beliefs about oneself or the world, mood changes and persistent feelings of anger, guilt or fear; alterations in arousal such as increased irritability, angry outbursts, being hypervigilant, or having difficulty with concentration and sleep.

Rachel Yehuda is a professor of psychiatry and neuroscience, the Vice Chair for Veterans Affairs in the Psychiatry Department, and the Director of the Traumatic Stress Studies Division at the Mount Sinai School of Medicine. She also leads the PTSD clinical research program at the Neurochemistry and Neuroendocrinology laboratory at the James J. Peters VA Medical Center. In 2020 she became director of the Center for Psychedelic Psychotherapy and Trauma Research at Mount Sinai.

<span class="mw-page-title-main">Post-traumatic stress disorder among athletes</span> Prevalence of PTSD among athletes

Posttraumatic stress disorder (PTSD) is a cognitive disorder, which may occur after a traumatic event. It is a psychiatric disorder, which may occur across athletes at all levels of sport participation.

<span class="mw-page-title-main">Richard Bryant (psychologist)</span> Australian psychologist

Richard Allan Bryant is an Australian medical scientist. He is Scientia Professor of Psychology at the University of New South Wales (UNSW) and director of the UNSW Traumatic Stress Clinic, based at UNSW and Westmead Institute for Medical Research. His main areas of research are posttraumatic stress disorder (PTSD) and prolonged grief disorder. On 13 June 2016 he was appointed a Companion of the Order of Australia (AC), for eminent service to medical research in the field of psychotraumatology, as a psychologist and author, to the study of Indigenous mental health, as an advisor to a range of government and international organisations, and to professional societies.

Andreas Maercker is a German clinical psychologist and international expert in traumatic stress-related mental disorders who works in Switzerland. He also contributed to lifespan and sociocultural aspects of trauma sequelae, e.g. the Janus-Face model of posttraumatic growth.

<span class="mw-page-title-main">MDMA-assisted psychotherapy</span> Controlled administration of psychoactive drug MDMA to facilitate psychotherapy efficacy

MDMA-assisted psychotherapy is the use of prescribed doses of MDMA as an adjunct to psychotherapy sessions. Research suggests that MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD), including Complex PTSD, might improve treatment effectiveness. In 2017, a Phase II clinical trial led to "breakthrough therapy" designation by the US Food and Drug Administration (FDA).

References

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  1. 1 2 3 "Emory University School of Medicine: Meet Our Faculty" accessed 10/11/11.
  2. 1 2 Raines, Laura: "A new approach to treating PTSD: Doctor wants to help vets live in the moment," Atlanta Journal Constitution, 2/24/08, accessed 10/11/11 Archived 2008-04-09 at the Wayback Machine
  3. 1 2 Duenwald, Mary: "Debate on Acne Drug's Safety Persists Over Two Decades." The New York Times, 1/22/2002. Accessed 10/11/11.
  4. "Death Claims Mrs. Bremner," The Daily Olympian, p. 1, Feb 14, 1966. Accessed at http://www.bremnerhistory.com/laurnellbremner/obituary.pdf on 10/11/11
  5. "M. Laurnell Bremner," The Daily Olympian, p. 2, Feb 14, 1966. Accessed at http://www.bremnerhistory.com/laurnellbremner/obituary.pdf on 10/11/11
  6. http://userwww.service.emory.edu/~jdbremn/
  7. Goleman, Daniel: "Severe Trauma May Damage the Brain as Well as the Psyche," The New York Times, 8/1/1995, accessed 10/11/11.
  8. "Post-Traumatic Stress Disorder: an Interview with J. Douglas Bremner", ISI Essential Science Indicators Special Topics (May 2004), accessed 10/11/11.
  9. Rice, Sabriya: "Are you taking too many meds?" CNNHealth, May 31, 2011. Accessed 10/11/11.
  10. "Transcript: Nancy Grace: Attorney Charged in Murder-for-Hire Plot Against Wife" accessed 10/11/11.
  11. Advocates for Responsible Care: Dialysis Crisis, accessed 10/11/11
  12. Pubmed articles by JD Bremner, accessed 10/11/11.
  13. International Society for Traumatic Stress Studies: Awards and Honors Archived 2011-09-28 at the Wayback Machine . Accessed 10/11/11.
  14. The 2011 Page International Screenwriters Awards Quarterfinalists, accessed 10/11/11.