Elizabeth Anne Bukusi

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Elizabeth Anne Bukusi FAAS is a research professor working within the field of obstetrics and gynaecology, and global health. [1] [2] Bukusi's main areas of research focus around sexually transmitted infections, women's health, reproductive health, and HIV care, prevention and treatment. [1] [3] Bukusi is the Chief Research Officer at the Kenya Medical Research Institute (KEMRI) and led a "landmark" study on the use of PrEP in Kenya. [4] [5]

Contents

Education

Bukusi gained her general medical degree, followed by her Masters in obstetrics and gynaecology from the University of Nairobi. [1] She then went on to earn a certificate in international health, Masters in public health (MPH) and a PhD from the University of Washington's Department of Epidemiology. [1] Subsequent qualifications include a post-graduate diploma in Research ethics from the University of Cape Town, then a Masters in Bioethics from the Sind Institute of Urology and Transplantation. [1]

Research

Bukusi's Masters in Public Health, completed in 2000, studied the male factor in bacterial vaginosis in Kenya, and her PhD then continued this path of research with her thesis titled: 'Bacterial Vaginosis: A Randomized Trial to Reduce Recurrence'. In 2006 Bukusi was awarded her PhD, and published a paper in the journal Sexually Transmitted Diseases, 'Bacterial vaginosis: risk factors among Kenyan women and their male partners'. [6]

In 2010 Bukusi published 'Genital hygiene practices of fishermen targeted for a topical microbicide intervention against sexually transmitted infections in Kisumu, Kenya', within the International Journal of STD and AIDS. [7]

Bukusi's academic roles include chief research officer at KEMRI; [3] chair of the Bioethics Society of Kenya; [8] research professor at the University of Washington; [1] honorary lecturer at Aga Khan University; [9] and volunteer clinical faculty professor at the University of California San Francisco. [1] Other outstanding studies she has participated in include; Association between Mycoplasma genitalium and acute endometritis. [10] Bacterial vaginosis associated with increased risk of Female-to-Male HIV-1 transmission: A prospective cohort analysis among African couples. [11] HIV/AIDS stigma and refusal of HIV testing among pregnant women in rural Kenya: Results from the MAMAS study. This study found that anticipations of HIV/AIDS stigma can be barriers to acceptance of HIV testing by pregnant women. [12] HIV pre-exposure prophylaxis for adolescent girls and young women in Africa: from efficacy trials to delivery. This article concluded that PrEP is feasible to implement in integrated reproductive health service delivery models to reach African AGYW. [13] Retention in care and patient-reported reasons for undocumented transfer or stopping care among HIV-infected patients on Antiretroviral therapy in Eastern Africa: application of a sampling-based approach. [14] Efficacy of isoniazid prophylactic therapy in prevention of tuberculosis in children: a meta–analysis. [15] Efficacy of single-dose human Papillomavirus vaccination among young African women. [16] Texting improves testing: a randomized trial of two-way SMS to increase postpartum prevention of mother-to-child transmission retention and infant HIV testing. This study established that text messaging significantly improved maternal postpartum visit attendance, but overall return rates for these visits remained low. [17] Efficacy of pre-exposure prophylaxis for HIV-1 prevention among high risk heterosexuals: subgroup analyses from the Partners PrEP Study. The study concluded that among higher-risk subgroups in the Partners PrEP Study, including groups solely of higher-risk women, both TDF alone and combined FTC/TDF PrEP had consistently high efficacy for HIV-1 protection. [18] Family model of HIV care and treatment: a retrospective study in Kenya. [19] Rethinking HIV prevention to prepare for oral PrEP implementation for young African women. [20] Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. [21] HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: a randomised, multicentre, open-label trial. This study did not find a substantial difference in HIV risk among the methods evaluated, and all methods were safe and highly effective. [22] Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective. [23] and Integrated delivery of antiretroviral treatment and Pre-exposure Prophylaxis to HIV-1–Serodiscordant couples: A prospective implementation study in Kenya and Uganda. [24]

References

  1. 1 2 3 4 5 6 7 "Elizabeth Bukusi | University of Washington - Department of Global Health". globalhealth.washington.edu. Retrieved 2019-10-02.
  2. ↑ "Professor Elizabeth Anne Bukusi — Ethox Centre". www.ethox.ox.ac.uk. Retrieved 2019-10-02.
  3. 1 2 "Elizabeth Bukusi, MBChB, MMed, MPH, PhD". Kenya Research and Training Center. Archived from the original on 2017-11-11. Retrieved 2019-10-02.
  4. ↑ "The unsung hero: Why Elizabeth Bukusi deserves accolades". The Star. Retrieved 2019-10-02.
  5. ↑ "Study proves 7,000 AIDS deaths can be prevented annually in Kenya". The Star. Retrieved 2019-10-02.
  6. ↑ Bukusi, Elizabeth A.; Cohen, Craig R.; Meier, Amalia S.; Waiyaki, Peter G.; Nguti, Rosemary; Njeri, Jane N.; Holmes, King K. (June 2006). "Bacterial Vaginosis: Risk Factors Among Kenyan Women and Their Male Partners". Sexually Transmitted Diseases. 33 (6): 361–367. doi: 10.1097/01.olq.0000200551.07573.df . ISSN   0148-5717. PMID   16547451. S2CID   74319392.
  7. ↑ Kwena, Z A; Bukusi, E A; Gorbach, P; Sharma, A; Sang, N M; Holmes, K K (June 2010). "Genital hygiene practices of fishermen targeted for a topical microbicide intervention against sexually transmitted infections in Kisumu, Kenya". International Journal of STD & AIDS. 21 (6): 435–440. doi:10.1258/ijsa.2010.010103. ISSN   0956-4624. PMC   6456332 . PMID   20606226.
  8. ↑ "Kenyan researchers rise to meet the complex challenges of Bioethics". The Star. Retrieved 2019-10-02.
  9. ↑ "Bukusi Elizabeth Anne | The AAS". aasciences.ac.ke. Retrieved 2019-10-02.[ permanent dead link ]
  10. ↑ Cohen, Craig R; Manhart, Lisa E; Bukusi, Elizabeth A; Astete, Sabina; Brunham, Robert C; Holmes, King K; Sinei, Samuel K; Bwayo, Job J; Totten, Patricia A (2002-03-02). "Association between Mycoplasma genitalium and acute endometritis" . The Lancet. 359 (9308): 765–766. doi:10.1016/S0140-6736(02)07848-0. ISSN   0140-6736. PMID   11888591. S2CID   36191700.
  11. ↑ Cohen, Craig R.; Lingappa, Jairam R.; Baeten, Jared M.; Ngayo, Musa O.; Spiegel, Carol A.; Hong, Ting; Donnell, Deborah; Celum, Connie; Kapiga, Saidi; Delany, Sinead; Bukusi, Elizabeth A. (2012-06-26). "Bacterial Vaginosis Associated with Increased Risk of Female-to-Male HIV-1 Transmission: A Prospective Cohort Analysis among African Couples". PLOS Medicine. 9 (6): e1001251. doi: 10.1371/journal.pmed.1001251 . ISSN   1549-1676. PMC   3383741 . PMID   22745608.
  12. ↑ Turan, Janet M.; Bukusi, Elizabeth A.; Onono, Maricianah; Holzemer, William L.; Miller, Suellen; Cohen, Craig R. (2011-08-01). "HIV/AIDS Stigma and Refusal of HIV Testing Among Pregnant Women in Rural Kenya: Results from the MAMAS Study". AIDS and Behavior. 15 (6): 1111–1120. doi:10.1007/s10461-010-9798-5. ISSN   1573-3254. PMC   3127002 . PMID   20827573.
  13. ↑ Celum, Connie L; Delany-Moretlwe, Sinead; Baeten, Jared M; Straten, Ariane; Hosek, Sybil; Bukusi, Elizabeth A; McConnell, Margaret; Barnabas, Ruanne V; Bekker, Linda-Gail (2019). "HIV pre-exposure prophylaxis for adolescent girls and young women in Africa: from efficacy trials to delivery". Journal of the International AIDS Society. 22 (S4): e25298. doi:10.1002/jia2.25298. ISSN   1758-2652. PMC   6643076 . PMID   31328444. S2CID   198133013.
  14. ↑ Geng, Elvin H. (2015). "Retention in Care and Patient-Reported Reasons for Undocumented Transfer or Stopping Care Among HIV-Infected Patients on Antiretroviral Therapy in Eastern Africa: Application of a Sampling-Based Approach". Clinical Infectious Diseases. 62 (7): 935–944. doi:10.1093/cid/civ1004. PMC   4787603 . PMID   26679625.
  15. ↑ Ayieko, James; Abuogi, Lisa; Simchowitz, Brett; Bukusi, Elizabeth A.; Smith, Allan H.; Reingold, Arthur (2014-02-20). "Efficacy of isoniazid prophylactic therapy in prevention of tuberculosis in children: a meta–analysis". BMC Infectious Diseases. 14 (1): 91. doi: 10.1186/1471-2334-14-91 . ISSN   1471-2334. PMC   3936889 . PMID   24555539.
  16. ↑ Barnabas, Ruanne V.; Brown, Elizabeth R.; Onono, Maricianah A.; Bukusi, Elizabeth A.; Njoroge, Betty; Winer, Rachel L.; Galloway, Denise A.; Pinder, Leeya F.; Donnell, Deborah; Wakhungu, Imelda; Congo, Ouma; Biwott, Charlene; Kimanthi, Syovata; Oluoch, Lynda; Heller, Kate B. (2022-04-26). "Efficacy of Single-Dose Human Papillomavirus Vaccination among Young African Women". NEJM Evidence. 1 (5): EVIDoa2100056. doi:10.1056/EVIDoa2100056. ISSN   2766-5526. PMC   9172784 . PMID   35693874.
  17. ↑ Odeny, Thomas A.; Bukusi, Elizabeth A.; Cohen, Craig R.; Yuhas, Krista; Camlin, Carol S.; McClelland, R. Scott (2014-09-24). "Texting improves testing: a randomized trial of two-way SMS to increase postpartum prevention of mother-to-child transmission retention and infant HIV testing". AIDS. 28 (15): 2307–2312. doi:10.1097/QAD.0000000000000409. ISSN   0269-9370. PMC   4834137 . PMID   25313586.
  18. ↑ Murnane, Pamela M.; Celum, Connie; Mugo, Nelly; Campbell, James D.; Donnell, Deborah; Bukusi, Elizabeth; Mujugira, Andrew; Tappero, Jordan; Kahle, Erin M.; Thomas, Katherine K.; Baeten, Jared M. (2013-08-24). "Efficacy of preexposure prophylaxis for HIV-1 prevention among high-risk heterosexuals: subgroup analyses from a randomized trial". AIDS. 27 (13): 2155–2160. doi:10.1097/QAD.0b013e3283629037. ISSN   0269-9370. PMC   3882910 . PMID   24384592.
  19. ↑ Lewis Kulzer, Jayne; Penner, Jeremy A; Marima, Reson; Oyaro, Patrick; Oyanga, Arbogast O; Shade, Starley B; Blat, Cinthia C; Nyabiage, Lennah; Mwachari, Christina W; Muttai, Hellen C; Bukusi, Elizabeth A; Cohen, Craig R (2012). "Family model of HIV care and treatment: a retrospective study in Kenya". Journal of the International AIDS Society. 15 (1): 8. doi: 10.1186/1758-2652-15-8 . ISSN   1758-2652. PMC   3298805 . PMID   22353553.
  20. ↑ Celum, Connie L; Delany-Moretlwe, Sinead; McConnell, Margaret; van Rooyen, Heidi; Bekker, Linda-Gail; Kurth, Ann; Bukusi, Elizabeth; Desmond, Chris; Morton, Jennifer; Baeten, Jared M (2015). "Rethinking HIV prevention to prepare for oral PrEP implementation for young African women". Journal of the International AIDS Society. 18 (4 Suppl 3): 20227. doi:10.7448/IAS.18.4.20227. PMC   4509892 . PMID   26198350.
  21. ↑ Baeten, Jared M.; Donnell, Deborah; Ndase, Patrick; Mugo, Nelly R.; Campbell, James D.; Wangisi, Jonathan; Tappero, Jordan W.; Bukusi, Elizabeth A.; Cohen, Craig R.; Katabira, Elly; Ronald, Allan; Tumwesigye, Elioda; Were, Edwin; Fife, Kenneth H.; Kiarie, James (2012-08-02). "Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women". New England Journal of Medicine. 367 (5): 399–410. doi:10.1056/NEJMoa1108524. ISSN   0028-4793. PMC   3770474 . PMID   22784037.
  22. ↑ Ahmed, Khatija; Baeten, Jared M; Beksinska, Mags; Bekker, Linda-Gail; Bukusi, Elizabeth A; Donnell, Deborah; Gichangi, Peter B; Heller, Kate B; Hofmeyr, G Justus; Justman, Jessica; Kasaro, Margaret Phiri; Kiarie, James; Louw, Cheryl; Mastro, Timothy D; Morrison, Charles S (2019-07-27). "HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: a randomised, multicentre, open-label trial". The Lancet. 394 (10195): 303–313. doi:10.1016/S0140-6736(19)31288-7. ISSN   0140-6736. PMC   6675739 . PMID   31204114. S2CID   186245753.
  23. ↑ Finocchario-Kessler, Sarah; Wexler, Catherine; Maloba, May; Mabachi, Natabhona; Ndikum-Moffor, Florence; Bukusi, Elizabeth (2016-06-04). "Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective". BMC Women's Health. 16 (1): 29. doi: 10.1186/s12905-016-0306-6 . ISSN   1472-6874. PMC   4893293 . PMID   27259656.
  24. ↑ Baeten, Jared M.; Heffron, Renee; Kidoguchi, Lara; Mugo, Nelly R.; Katabira, Elly; Bukusi, Elizabeth A.; Asiimwe, Stephen; Haberer, Jessica E.; Morton, Jennifer; Ngure, Kenneth; Bulya, Nulu; Odoyo, Josephine; Tindimwebwa, Edna; Hendrix, Craig; Marzinke, Mark A. (2016-08-23). "Integrated Delivery of Antiretroviral Treatment and Pre-exposure Prophylaxis to HIV-1–Serodiscordant Couples: A Prospective Implementation Study in Kenya and Uganda". PLOS Medicine. 13 (8): e1002099. doi: 10.1371/journal.pmed.1002099 . ISSN   1549-1676. PMC   4995047 . PMID   27552090.
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