Author | Patrick Radden Keefe |
---|---|
Publisher | Doubleday |
Publication date | April 13, 2021 |
Pages | 560 |
ISBN | 978-0-385-54568-6 |
Empire of Pain: The Secret History of the Sackler Dynasty is a 2021 book by Patrick Radden Keefe. The book examines the history of the Sackler family, including the founding of Purdue Pharma, its role in the marketing of pharmaceuticals, and the family's central role in the opioid epidemic. [1] [2] [3] The book followed Keefe's 2017 article on the Sackler family in The New Yorker , titled "The Family That Built an Empire of Pain". [4] [5]
Arthur, Mortimer, and Raymond Sackler were children of Jewish immigrants that were raised in Brooklyn. All three brothers became medical doctors, but the eldest, Arthur, showed a particular talent for advertising, combining both his passions by joining and later owning William Douglas McAdams Inc., an advertising firm that exclusively handled medicinal clients and pioneered the technique of advertising medication directly to doctors. Despite having many conflicts of interest, Arthur was able to keep these associations hidden by leaving his brothers, friends, and ex-wife as figureheads for various companies. As Arthur continued to amass his fortune, he and his younger brothers begin to make important philanthropic contributions, donating money to museums and for scholarships. The brothers eventually grew estranged; when Arthur died in 1987, his complicated legacy was left to multiple heirs including his brothers, his wife, his ex-wife, and his four children. When the fight to split the assets devolved into acrimony, his children agreed to sell their shares in Purdue Frederick, a small drug manufacturer, to their uncles Mortimer and Raymond.
Mortimer and Raymond Sackler invested in research into opioids with their investment in research eventually leading to Oxycodone. After Mortimer and Raymond joined the board at Purdue Frederick, the family began to roll out a sales force to sell Oxycodone using techniques pioneered by Arthur in order to influence politicians, government officials and doctors into endorsing the pill. Their new drug was an immediate success, but almost equally quickly, users began to abuse the drug. In 2010, the company discontinued their initial version of the drug and made a version that was impossible to crush; this led to a 25% drop in sales and a rise in heroin which was arguably caused by opioid abuse. As lawsuits began to build against Purdue Frederick, the Sackler family sought to insulate themselves both financially and publicly from the drug. All Sacklers declined interviews and the Sacklers on the board of the company repeatedly voted to give themselves huge financial bonuses.
By 2017, a series of articles linking the Sacklers to Oxycodone as well as a public campaign by photographer Nan Goldin to link the Sacklers to the opioid crisis, led to stigmatization of the Sackler name with many museums and universities refusing financial gifts from the Sacklers.
While the family was eventually sued, the Sacklers used their company to declare bankruptcy, link their personal finances to the fortunes of Purdue Frederick, and ultimately managed to escape any financial consequences at all. The family continued to maintain that they knew nothing about the abusive and deceptive marketing practices of the company and maintained the lie that their opioids were not addictive and that the few people who abused their drugs were already addicts to begin with.
The book received critical acclaim. [6] According to Book Marks, the book received a "rave" consensus, based on seventeen critic reviews: twelve "rave" and five "positive". [7] In Books in the Media, a site that aggregates critic reviews of books, the book received a rating of 4.20 out of 5, based on seven critic reviews. [8] [9]
New York noted that Empire of Pain differs from other coverage of the Sackler's role in the opioid crisis, calling the book "principally a family history". [10] Zachary Siegel, writing in The New Republic , called the book an "important record of private greed facilitated by a corrupted government". [11] Publishers Weekly called the book a "damning review" of the family's involvement in the opioid epidemic. [12] Joanna Walter praised Patrick Radden Keefe's telling of the decade-spanning story in Literary Review : "He expertly draws all the threads together to bring us the full, frightening saga... the sum of its parts is a stunning crime story." [13]
The book won the 2021 Baillie Gifford Prize for Non-fiction and the Goodreads Choice Award for History & Biography, [14] was shortlisted for the 2021 Financial Times and McKinsey Business Book of the Year Award, and was longlisted for the 2022 Andrew Carnegie Medal for Excellence in Nonfiction. [15] [16] [17] It was also selected for The Washington Post 's "10 Best Books of 2021" list. [18]
Arthur Mitchell Sackler was an American psychiatrist and marketer of pharmaceuticals whose fortune originated in medical advertising and trade publications. He was also an art collector. He was one of the three patriarchs of the controversial Sackler family pharmaceutical dynasty.
Purdue Pharma L.P., formerly the Purdue Frederick Company (1892–2019), was an American privately held pharmaceutical company founded by John Purdue Gray. It was sold to Arthur, Mortimer, and Raymond Sackler in 1952, and then owned principally by the Sackler family and their descendants.
Raymond Sackler was an American physician and businessman. He acquired Purdue Pharma together with his brothers Arthur M. Sackler and Mortimer Sackler. Purdue Pharma is the developer of OxyContin, the drug at the center of the opioid epidemic in the United States.
Mortimer David Sackler was an American-born psychiatrist and entrepreneur. He co-owned Purdue Pharma with his brothers Arthur and Raymond. During his lifetime, Sackler's philanthropy included donations to the Metropolitan Museum of Art, the Tate Gallery, the Royal College of Art, the Louvre, and Berlin's Jewish Museum.
Reputation laundering occurs when a person or an organization conceals unethical, corrupt, or criminal behavior or other forms of controversy by performing highly visible positive actions with the intent to improve their reputation and obscure their history.
Elizabeth Ann Sackler is a public historian, arts activist, and the daughter of Arthur M. Sackler and descendant of the Sackler family. She is the founder of the American Indian Ritual Object Repatriation Foundation and the Elizabeth A. Sackler Center for Feminist Art at the Brooklyn Museum.
Patrick Radden Keefe is an American writer and investigative journalist. He is the author of five books—Chatter,The Snakehead,Say Nothing,Empire of Pain, and Rogues—and has written extensively for many publications, including The New Yorker, Slate, and The New York Times Magazine. He is a staff writer at The New Yorker.
Richard Stephen Sackler is an American businessman and physician who was the chairman and president of Purdue Pharma, a former company best known as the developer of OxyContin, whose role in the opioid epidemic in the United States became the subject of many lawsuits and fines, filing for bankruptcy in 2019. The company's downfall was the subject of the 2021 Hulu miniseries Dopesick and the 2023 Netflix miniseries Painkiller, in which Sackler is portrayed by Michael Stuhlbarg and Matthew Broderick, respectively.
Madeleine Sackler is an American filmmaker and Sackler family heiress. She received an Emmy Award in 2015 and was nominated for a second in 2020. Her grandfather, Raymond, was one of the three Sackler brothers who created and owned Purdue Pharma, infamous for its role in the Opioid epidemic. She has received criticism for her family fortune, which derives mostly from the sale and manufacture of the highly addictive pharmaceutical opioid Oxycontin, the central drug in the opioid crisis.
O.G. is a 2018 American drama film directed by Madeleine Sackler and written by Stephen Belber. The film stars Jeffrey Wright, William Fichtner, Boyd Holbrook, Mare Winningham, David Patrick Kelly and Yul Vazquez. The film premiered on HBO on February 23, 2019. The film was entirely filmed in Pendleton Correctional Facility, a maximum security prison in Indiana.
Massachusetts v. Purdue is a lawsuit filed on August 14, 2018, suing the Stamford, Connecticut-based company Purdue Pharma LP, which created and manufactures OxyContin, "one of the most widely used and prescribed opioid drugs on the market", and Purdue's owners, the Sacklers accusing them of "widespread fraud and deception in the marketing of opioids, and contributing to the opioid crisis, the nationwide epidemic that has killed thousands." Purdue denied the allegations.
Barry Meier is a writer and former New York Times journalist who wrote the 2003 non-fiction book Pain Killer: A Wonder Drug's Trail of Addiction and Death. His articles "have led to Congressional hearings and changes in federal laws".
The Sackler family is an American family who owned the pharmaceutical company Purdue Pharma and later founded Mundipharma. Purdue Pharma, and some members of the family, have faced lawsuits regarding overprescription of addictive pharmaceutical drugs, including OxyContin. Purdue Pharma has been criticized for its role in the opioid epidemic in the United States. They have been described as the "most evil family in America", and "the worst drug dealers in history".
Napp Pharmaceuticals Limited is a private pharmaceutical company in Cambridge, United Kingdom that was founded in 1923 and bought by the Sackler family in 1966. Headquartered together with the related Napp Research Centre in the Cambridge Science Park since the 1980s, it is a sister company of Purdue Pharma and Mundipharma, all of which are owned by the descendants of Mortimer and Raymond Sackler.
The timeline of the opioid epidemic includes selected events related to the origins of Stamford, Connecticut-based Purdue Pharma, the Sackler family, the development and marketing of oxycodone, selected FDA activities related to the abuse and misuse of opioids, the recognition of the opioid epidemic, the social impact of the crisis, lawsuits against Purdue and the Sackler family.
The Crime of the Century is an American two-part documentary film directed, produced, and written by Alex Gibney. The film follows the opioid epidemic in the United States, and the political operatives, government regulations and corporations that enable the abuse of opioids, particularly the Sackler family and Purdue Pharma.
Joss Sackler is a fashion designer. She is also known for her marriage to David Sackler, whose father Richard Sackler was the chairman and president of Purdue Pharma, and oversaw its manufacturing of the highly addictive opioid Oxycontin, a leading drug in the opioid epidemic.
Curtis Wright IV is an American former government official known for his role in the Food and Drug Administration's approval of OxyContin for Purdue Pharma in 1995, followed by his subsequent employment by the company, which led to portrayals in films and reports in nonfiction books, magazines, and news media outlets of his alleged role as one of the key figures in the current opioid epidemic in the United States. Wright was implicated in a criminal conspiracy outlined in a 2006 United States Department of Justice review document that was first made public in Purdue Pharma's 2019 bankruptcy proceedings. Although that case was settled in a 2007 plea agreement deal, members of United States Congress have requested the full 2006 documentation from the Department of Justice with the goal of opening a new case based upon the evidence then gathered. Parts of Wright's sworn depositions in 2003 and 2018 have internal contradictions and differ from documentary evidence described the 2003–2006 U.S. Federal Government investigation into Purdue Pharma.
Painkiller is an American drama television miniseries created by Micah Fitzerman-Blue and Noah Harpster. Based on Patrick Radden Keefe's New Yorker article "The Family That Built an Empire of Pain" and Pain Killer: An Empire of Deceit and the Origin of America's Opioid Epidemic by Barry Meier, the series focuses on the birth of the opioid crisis, with an emphasis on Purdue Pharma, the company owned by Richard Sackler and his family that was the manufacturer of OxyContin. The Sackler family has been described as the "most evil family in America", and "the worst drug dealers in history".
The Sackler Wing (1978) is located at The Met Fifth Avenue, the Metropolitan Museum of Art's flagship location in New York City. Designed by Kevin Roche and located to the north of the museum's original building, the wing was built to house the Temple of Dendur, brought from Egypt to New York.