Oxycodone, sold under various brand names such as Roxicodone and OxyContin, is a semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive and is a commonly abused drug. It is usually taken by mouth, and is available in immediate-release and controlled-release formulations. Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation. In the United Kingdom, it is available by injection. Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin.
Arthur Mitchell Sackler was an American psychiatrist and marketer of pharmaceuticals whose fortune originated in medical advertising and trade publications. He was also an art collector. He was one of the three patriarchs of the controversial Sackler family pharmaceutical dynasty.
Purdue Pharma L.P., formerly the Purdue Frederick Company (1892–2019), was an American privately held pharmaceutical company founded by John Purdue Gray. It was sold to Arthur, Mortimer, and Raymond Sackler in 1952, and then owned principally by the Sackler family and their descendants.
Raymond Sackler was an American physician and businessman. He acquired Purdue Pharma together with his brothers Arthur M. Sackler and Mortimer Sackler. Purdue Pharma is the developer of OxyContin, the drug at the center of the opioid epidemic in the United States.
Mortimer David Sackler was an American-born psychiatrist and entrepreneur who was a co-owner, with his brothers Arthur and Raymond, of Purdue Pharma. During his lifetime, Sackler's philanthropy included donations to the Metropolitan Museum of Art, the Tate Gallery, the Royal College of Art, the Louvre and Berlin's Jewish Museum.
Reputation laundering occurs when a person or an organization conceals unethical, corrupt, or criminal behavior or other forms of controversy by performing highly visible positive actions with the intent to improve their reputation and obscure their history.
Elizabeth Ann Sackler is a public historian, arts activist, and the daughter of Arthur M. Sackler; as such, she is a member of the Sackler family. She is the founder of the American Indian Ritual Object Repatriation Foundation and the Elizabeth A. Sackler Center for Feminist Art at the Brooklyn Museum.
Patrick Radden Keefe is an American writer and investigative journalist. He is the author of five books—Chatter,The Snakehead,Say Nothing,Empire of Pain, and Rogues—and has written extensively for many publications, including The New Yorker, Slate, and The New York Times Magazine. He is a staff writer at The New Yorker.
Richard Stephen Sackler is an American billionaire businessman and physician who was the chairman and president of Purdue Pharma, a former company best known as the developer of OxyContin, whose connection to the opioid epidemic in the United States was the subject of multiple lawsuits and fines, and that filed for bankruptcy in 2019. It has been claimed that Richard Sackler's Purdue is among ”the worst drug dealers in history” and the Sackler family have been described as the "most evil family in America". The company's downfall was the subject of the 2021 Hulu series Dopesick and the 2023 Netflix series Painkiller.
Madeleine Sackler is an American filmmaker, heiress, and member of the Sackler family. She received an Emmy in 2015 and was nominated for a second one in 2020. Her grandfather, Raymond, was one of the three Sackler brothers who created and owned Purdue Pharma, infamous for its role in the Opioid epidemic. She has received criticism for her family fortune, which derives mostly from the sale and manufacture of the highly addictive pharmaceutical opioid Oxycontin, the central drug in the opioid crisis.
O.G. is a 2018 American drama film directed by Madeleine Sackler and written by Stephen Belber. The film stars Jeffrey Wright, William Fichtner, Boyd Holbrook, Mare Winningham, David Patrick Kelly and Yul Vazquez. The film premiered on HBO on February 23, 2019. The film was entirely filmed in Pendleton Correctional Facility, a maximum security prison in Indiana.
Massachusetts v. Purdue is a lawsuit filed on August 14, 2018, suing the Stamford, Connecticut-based company Purdue Pharma LP, which created and manufactures OxyContin, "one of the most widely used and prescribed opioid drugs on the market", and Purdue's owners, the Sacklers accusing them of "widespread fraud and deception in the marketing of opioids, and contributing to the opioid crisis, the nationwide epidemic that has killed thousands." Purdue denied the allegations.
The Sackler family is an American family who owned the pharmaceutical company Purdue Pharma and later founded Mundipharma. Purdue Pharma, and some members of the family, have faced lawsuits regarding overprescription of addictive pharmaceutical drugs, including OxyContin. Purdue Pharma has been criticized for its role in the opioid epidemic in the United States. They have been described as the "most evil family in America", and "the worst drug dealers in history".
Napp Pharmaceuticals Limited is a private pharmaceutical company in Cambridge, United Kingdom that was founded in 1923 and bought by the Sackler family in 1966. Headquartered together with the related Napp Research Centre in the Cambridge Science Park since the 1980's, it is a sister company of Purdue Pharma and Mundipharma, all of which are owned by the descendants of Mortimer and Raymond Sackler.
The timeline of the opioid epidemic includes selected events related to the origins of Stamford, Connecticut-based Purdue Pharma, the Sackler family, the development and marketing of oxycodone, selected FDA activities related to the abuse and misuse of opioids, the recognition of the opioid epidemic, the social impact of the crisis, lawsuits against Purdue and the Sackler family.
The Crime of the Century is an American two-part documentary film, directed, produced, and written by Alex Gibney. The film follows the opioid epidemic in the United States, and the political operatives, government regulations and corporations that enable the abuse of opioids, particularly the Sackler family and Purdue Pharma.
Joss Sackler is a fashion designer. She is also known for her marriage to David Sackler, whose father Richard Sackler was the chairman and president of Purdue Pharma, and oversaw its manufacturing of the highly addictive opioid Oxycontin, a leading drug in the opioid epidemic.
Curtis Wright IV is an American former government official known for his role in the Food and Drug Administration's approval of OxyContin for Purdue Pharma in 1995, followed by his subsequent employment by the company, which led to portrayals in films and reports in nonfiction books, magazines, and news media outlets of his alleged role as one of the key figures in the current opioid epidemic in the United States. Wright was implicated in a criminal conspiracy outlined in a 2006 United States Department of Justice review document that was first made public in Purdue Pharma's 2019 bankruptcy proceedings. Although that case was settled in a 2007 plea agreement deal, members of United States Congress have requested the full 2006 documentation from the Department of Justice with the goal of opening a new case based upon the evidence then gathered. Parts of Wright's sworn depositions in 2003 and 2018 have internal contradictions and differ from documentary evidence described the 2003–2006 U.S. Federal Government investigation into Purdue Pharma.
Painkiller is an American drama limited series made for Netflix and created by Micah Fitzerman-Blue and Noah Harpster. The six-episode series, which is based on Patrick Radden Keefe's New Yorker article "The Family That Built an Empire of Pain" and Pain Killer: An Empire of Deceit and the Origin of America's Opioid Epidemic by Barry Meier, focuses on the birth of the opioid crisis, with an emphasis on Purdue Pharma, a company owned by Richard Sackler and his family that was the manufacturer of OxyContin. The Sackler family has been described as the "most evil family in America", and "the worst drug dealers in history".
The Sackler Wing (1978) is located at The Met Fifth Avenue, the Metropolitan Museum of Art's flagship location in New York City. Designed by Kevin Roche and located to the north of the museum's original building, the wing was built to house the Temple of Dendur, brought from Egypt to New York.
