Personal life
Rubin was born and raised in Brockton, Massachusetts. His father, Morris Rubin, was a salesman and his mother, Paula (Schechet) Rubin, was a school librarian. He is married to Akiyo Fujii and has two children, Alexander and Daniel.
Education and career
Rubin graduated from Brockton High School, Harvard College (AB, 1980) and Tufts University (MD and PhD, 1990). [4] As a graduate student he studied the mechanism of action of botulinum toxins with Dr. Michael Gill. [5] Rubin trained in Internal Medicine and Infectious Disease at the Massachusetts General Hospital [6] and went on to postdoctoral work in John Mekalanos [7] lab at Harvard Medical School. There he studied Vibrio cholerae, Haemophilus influenzae and Mycobacterium smegmatis. [5] His postdoctoral work included collaborating on the development of a widely used transposition system based on the Himar1 transposon along with the methods for mapping mutations on a genome-wide basis. [8]
Rubin joined the Department of Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health in 1999, eventually becoming the Irene Heinz Given Professor and Chair of the Department. [9] His lab studies mycobacterial physiology and virulence and has developed many of the genetic tools used to study Mycobacterium tuberculosis and related organisms. [10] With collaborators, the lab has used these tools to address a wide range of questions about tuberculosis pathogenesis, non-tuberculous mycobacteria, and drug and vaccine development. [11] He is also an infectious disease clinician who sees patients at Brigham and Women’s Hospital, where he is an Associate Physician. [1]
In 2019, Rubin was appointed Editor-in-Chief of the Journal, where he had previously served as an Associate Editor, and NEJM Group, the publishing division of the Massachusetts Medical Society. [3] During the Covid-19 outbreak, the Journal added a weekly podcast [12] and rapidly published many studies, including the first description of SARS-CoV-2, the causative virus. [13] During Rubin’s tenure, NEJM Group has also launched two more publications, NEJM Evidence [14] and NEJM AI. [15]
Rubin has worked extensively in international settings and has been involved on advisory boards for several national and global organizations. He is a member of the American Academy of Microbiology, the American Association of Physicians, and the National Academy of Medicine. [5] He also serves on the Food and Drug Administration’s Vaccines and Related Biological Products Advisory Committee (VRBPAC). [16]
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