Eva Braak

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Eva Braak
Eva braak.jpg
Born(1939-11-26)November 26, 1939
Died(2000-07-25)July 25, 2000
EducationGeorg August University, Vogt Institute for Brain Research - University of Dusseldorf, University of Kiel
Occupations Anatomist, professor

Eva Braak (1939-2000) was a German anatomist, mostly known for the Braak and Braak Alzheimer disease stages. She was professor at the Institute of Clinical Neuroanatomy, Johann Wolfgang Goethe-University, Frankfurt am Main.

Contents

Education

Eva Foh [1] was born on 26 November 1939 in Schönwald (Sudetenland). She received a PhD in biology in 1967 from the Georg August University of Göttingen, followed by postdoctoral training at the Institute of Brain Research in Neustadt where she studied with Cécile Vogt-Mugnier and Oskar Vogt (1967–1971). In 1971, she moved to the Christian Albrecht University of Kiel, Germany. There she met her future co-researcher and husband, Heiko Braak. [2] They were married in 1973. [3] In 1978 Eva completed her Habilitation in medicine, and became a lecturer in the Department of Anatomy. In 1979, [3] or 1980 [2] they moved to Frankfurt am Main to work with the Medical Faculty of Johann Wolfgang Goethe-Universität Frankfurt am Main. Eva was appointed to the rank of Associate Professor in the Department of Clinical Neuroanatomy. [3]

Career

Eva Braak and her husband, Heiko Braak, were in charge of a group investigating new techniques in the study of degenerative diseases of the brain [4] [5] In the 1970s, Braak and her husband implemented and perfected the then-new silver-iodate histological technique to study relatively thick sections of whole brains, up to 1000 microns. [5] [2] Using those methods, they contributed extensively to the neuropathology of Alzheimer's and Parkinson's diseases. In 1987, Braak and her husband were the first to describe the pathological changes of argyrophilic grain disease, an unknown tauopathy which was previously marked as senile dementia. [3] A few years later, in 1991, they introduced a classification of Alzheimer's disease into six distinct pathoanatomical stages, now commonly known as Braak and Braak stages, based on the topographical distribution pattern of neurofibrillary changes from circumscribed parts of the limbic system to the higher neocortical association fields. [5]

Awards

Eva Braak was the first female scientist to receive an Award for Life-time Achievements in Alzheimer's Disease Research, granted during the Sixth International Conference on Alzheimer's Disease and related Disorders, in 1998 [2] by the Alzheimer’s Association International Conference. [6]

Death

Eva Braak died of ovarian cancer on 25 August 2000 in Frankfurt am Main. [3]

Selected publications

References

  1. "FNB 3". Uni Kiel (in German). 23 December 2025. Retrieved 23 December 2025.
  2. 1 2 3 4 Ohm, Thomas (7 August 2001). "Eva Braak (1939–2000)". Journal of Alzheimer's Disease. 3 (4): 433–434. doi:10.3233/JAD-2001-3413. ISSN   1387-2877.
  3. 1 2 3 4 5 Iqbal, Khalid; Sisodia, Sangram S.; Winblad, Bengt (2001). "Eva Braak, 'Outstanding but unassuming'". Alzheimer's disease: advances in etiology, pathogenesis and therapeutics. Chichester: Wiley. pp. xxvi–xxvii. ISBN   0-471-52176-0.
  4. Bermejo-Pareja, F; Del Ser, T (31 October 2025). "Alzheimer Syndrome or Age-Related Dementia-History, Therapy and Prevention". Journal of Clinical Medicine. 14 (21): 7752. doi: 10.3390/jcm14217752 . PMC   12607965 . PMID   41227148.
  5. 1 2 3 Beach, TG (20 May 2022). "A History of Senile Plaques: From Alzheimer to Amyloid Imaging". Journal of Neuropathology and Experimental Neurology. 81 (6): 387–413. doi:10.1093/jnen/nlac030. ISSN   1554-6578. PMC   9122832 . PMID   35595841.
  6. "AAIC Lifetime Achievement Awards | Alzheimer's Association". AAIC Lifetime Achievement Awards | Alzheimer's Association. Retrieved 23 December 2025.