Extracorporeal Life Support Organization

Extracorporeal Life Support Organization

Company type	non-profit organization
Industry	Health care
Founded	1989
Headquarters	Ann Arbor, MI , United States
Website	http://www.elso.org/

The Extracorporeal Life Support Organization (ELSO) is a non profit organization established in 1989 supporting health care professionals and scientists who are involved in extracorporeal membrane oxygenation (ECMO). ^[1] ELSO maintains a registry of both facilities and specialists trained to provide ECMO services. ELSO also maintains registry information that is used to support clinical research, support regulatory agencies, and support individual ELSO centers. ELSO provides educational programs for active centers as well as for facilities who may be involved in the transfer of patients to higher levels of care. ^[2]

ELSO Chapters

In addition to the North American-based ELSO organization, chapters have been developed to represent the regional needs of ELSO in the rest of the world. Current chapters ^[3] include:

• Euro-ELSO – Founded in 2011 to serve the European region. Dr. Jan Belohlavek is the current chairman. ^[4]
• Asia-Pacific ELSO – Founded in 2012 to serve the Asian and Pan-Pacific region. Dr. John Fraser is the current chairman. ^[5]
• Latin American ELSO – Founded in 2012 to serve the Central and South American region. Dr. Leonardo Salazar is the current chairman. ^[6]
• South and West Asia and Africa ELSO ^[7] – Founded in 2013 to serve the Southern and Western Asian region and Africa. Dr. Yatin Mehta is the current chairman.

ELSO Registry

Since 1989, ELSO has maintained a registry of clinical characteristics and outcomes of patients supported with ECMO. A history of the ELSO registry has been published and demonstrates how it evolved over time from paper documentation, to a modern database with web based data entry. ^[8] Data managers at each of the ELSO centers use detailed database definitions and a point-of-entry data warning system to minimize errors in data entry, as well as full record validation triggered upon submission of the record to ensure all mandatory fields are completed. The ELSO registry has been instrumental in improving ECMO care, post-cardiac arrest management, pediatric ventricular assist devices, and organ transplantation. ^[9]

The last formally published ELSO Registry report was in 2017, and contained clinical characteristics, complications, and outcomes of 78,397 patients supported with ECMO. ^[10] Demonstrating the rapid growth of ECMO, at the beginning of 2020, the ELSO Registry contained information on 129,037 patients from 435 member centers across the world. ^[11]

With the onset of the COVID-19 pandemic, the ELSO registry began collecting data on the worldwide use of ECMO for patients with COVID-19 and reporting this data on the ELSO website in real time. In September 2020, the outcomes of 1,035 COVID-19 patients supported with ECMO from 213 experienced centers in 36 different countries were published in The Lancet, and demonstrated 38% mortality, which is similar to many other respiratory diseases treated with ECMO. ^[12]

Recommended ECMO specialists

• Respiratory therapist holding a certificate as a Registered Respiratory Therapist
• Registered nurse with at least one year of intensive care unit experience.
• Clinical perfusionist graduating from a school of perfusion.

Guidelines for care

ELSO promulgates guidelines ^[13] for the care of patients on ECMO. They include overall guidelines about setting up a program, proper equipment, and patient care for certain medical conditions. Additional education on ECMO topics is provided through ELSO published textbooks and training manuals for ECMO specialists. ^[14] ELSO recognizes centers with exceptional programs, systems, processes, and outcomes with the Award for Excellence in Life Support. ^[15]

• Extracorporeal Life Support Organization (ELSO): Guidelines for Neonatal Respiratory Failure ^[16]

Position statements

ELSO provides position statements on:

• Organization of ECMO programs for acute respiratory failure in adult patients ^[17]
• Joint Statement on Mechanical Circulatory Support in Children: A Consensus Review from the Pediatric Cardiac Intensive Care Society and ELSO ^[18]
• Use of ECMO in Ebola virus disease ^[19]
• Position Paper on Global Extracorporeal Membrane Oxygenation Education and Educational Agenda for the Future: A Statement From the Extracorporeal Life Support Organization ECMOed Taskforce ^[20]
• Joint Society of Critical Care Medicine-Extracorporeal Life Support Organization Task Force Position Paper on the Role of the Intensivist in the Initiation and Management of Extracorporeal Membrane Oxygenation ^[21]
• The ELSO Maastricht Treaty for ECLS Nomenclature: abbreviations for cannulation configuration in extracorporeal life support - a position paper of the Extracorporeal Life Support Organization ^[22]
• Use of ECMO in COVID-19 ^{[23] [24]}

References

1. Cooper DS, Jacobs JP, Moore L, Stock A, Gaynor JW, Chancy T, et al. (2007). "Cardiac extracorporeal life support: state of the art in 2007". Cardiol Young. 17 (Suppl 2): 104–15. doi:10.1017/S1047951107001217. PMID   18039404. S2CID   206304339.
2. Kim K, Mazor RL, Rycus PT, Brogan TV (2011). "Use of venovenous extracorporeal life support in pediatric patients for cardiac indications: A review of the Extracorporeal Life Support Organization registry". Pediatr Crit Care Med. 13 (3): 285–9. doi:10.1097/PCC.0b013e31822f1586. PMID   21926665. S2CID   24492898.
3. "Extracorporeal Life Support Organization - ECMO and ECLS > Members > Chapters". www.elso.org. Retrieved 2015-09-17.
4. "Euro-ELSO". www.euroelso.net. Retrieved 2020-05-09.
5. "AP-ELSO". www.elso.org. Retrieved 2020-05-12.
6. "LA-ELSO". www.elso.org. Retrieved 2020-05-12.
7. "South and West Asia Africa chapter Elso | ECMO Society of India". www.swac-elso.com. Archived from the original on 2014-12-22. Retrieved 2015-09-17.
8. Lorusso, Roberto; Alexander, Peta; Rycus, Peter; Barbaro, Ryan (January 2019). "The Extracorporeal Life Support Organization Registry: update and perspectives". Annals of Cardiothoracic Surgery. 8 (1): 93–98. doi: 10.21037/acs.2018.11.03 . PMC   6379190 . PMID   30854317.
9. Nasr, Viviane G.; Raman, Lakshmi; Barbaro, Ryan P.; Guner, Yigit; Tonna, Joseph; Ramanathan, Kollengode; Pappalardo, Federico; Thiagarajan, Ravi R.; Alexander, Peta M.A. (August 2019). "Highlights from the Extracorporeal Life Support Organization Registry: 2006–2017". ASAIO Journal. 65 (6): 537–544. doi: 10.1097/MAT.0000000000000863 . ISSN   1058-2916. PMID   30074497. S2CID   51905235.
10. Thiagarajan, Ravi R.; Barbaro, Ryan P.; Rycus, Peter T.; Mcmullan, D. Michael; Conrad, Steven A.; Fortenberry, James D.; Paden, Matthew L. (2017). "Extracorporeal Life Support Organization Registry International Report 2016" . ASAIO Journal. 63 (1): 60–67. doi:10.1097/MAT.0000000000000475. ISSN   1058-2916. PMID   27984321. S2CID   205758344.
11. "Extracorporeal Life Support Organization - ECMO and ECLS > Registry > Statistics > International Summary". www.elso.org. Retrieved 2020-05-12.
12. Barbaro, Ryan P.; MacLaren, Graeme; Boonstra, Philip S.; Iwashyna, Theodore J.; Slutsky, Arthur S.; Fan, Eddy; Bartlett, Robert H.; Tonna, Joseph E.; Hyslop, Robert; Fanning, Jeffrey J.; Rycus, Peter T. (2020-09-25). "Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry". The Lancet. 396 (10257): 1071–1078. doi: 10.1016/S0140-6736(20)32008-0 . ISSN   0140-6736. PMC   7518880 . PMID   32987008.
13. "Extracorporeal Life Support Organization - ECMO and ECLS > Resources > Guidelines". www.elso.org. Retrieved 2015-09-17.
14. "Extracorporeal Life Support Organization - ECMO and ECLS > Publications". www.elso.org. Retrieved 2015-09-17.
15. "Extracorporeal Life Support Organization - ECMO and ECLS > Excellence > Vision". www.elso.org. Retrieved 2015-09-17.
16. Wild, K. Taylor; Rintoul, Natalie; Kattan, Javier; Gray, Brian; Engle, Reviewers: William; Keene, Sarah; Best, Derek; Davis, Carl; DiGeronimo, Robert; Raman, Lakshmi (May 2020). "Extracorporeal Life Support Organization (ELSO): Guidelines for Neonatal Respiratory Failure". ASAIO Journal. 66 (5): 463–470. doi: 10.1097/MAT.0000000000001153 . ISSN   1058-2916. PMID   32282347.
17. Combes, Alain; Brodie, Daniel; Bartlett, Robert; Brochard, Laurent; Brower, Roy; Conrad, Steve; De Backer, Daniel; Fan, Eddy; Ferguson, Niall (2014-07-25). "Position Paper for the Organization of Extracorporeal Membrane Oxygenation Programs for Acute Respiratory Failure in Adult Patients". American Journal of Respiratory and Critical Care Medicine. 190 (5): 488–96. doi:10.1164/rccm.201404-0630CP. hdl: 2434/238408 . ISSN   1073-449X. PMID   25062496.
18. MacLaren, Graeme; Dodge-Khatami, Ali; Dalton, Heidi J. (2013-01-01). "Joint Statement on Mechanical Circulatory Support in Children" . Pediatric Critical Care Medicine. 14 (5 Suppl 1): S1 –S2. doi:10.1097/pcc.0b013e318292dc09. PMID   23735979.
19. "Extracorporeal Life Support Organization - ECMO and ECLS > Ebola Statement". www.elso.org. Retrieved 2015-09-17.
20. Zakhary, Bishoy; Shekar, Kiran; Diaz, Rodrigo; Badulak, Jenelle; Johnston, Lindsay; Roeleveld, Peter Paul; Alinier, Guillaume; Lai, Peter Chi Keung; Ramanathan, Kollengode; Moore, Elizabeth; Hassan, Ibrahim (March 2020). "Position Paper on Global Extracorporeal Membrane Oxygenation Education and Educational Agenda for the Future: A Statement From the Extracorporeal Life Support Organization ECMOed Taskforce*". Critical Care Medicine. 48 (3): 406–414. doi:10.1097/CCM.0000000000004158. hdl: 2299/23778 . ISSN   0090-3493. PMID   31833901. S2CID   209342469.
21. DellaVolpe, Jeffrey; Barbaro, Ryan P.; Cannon, Jeremy W.; Fan, Eddy; Greene, Wendy R.; Gunnerson, Kyle J.; Napolitano, Lena M.; Ovil, Ace; Pamplin, Jeremy C.; Schmidt, Matthieu; Sorce, Lauren R. (April 2020). "Joint Society of Critical Care Medicine-Extracorporeal Life Support Organization Task Force Position Paper on the Role of the Intensivist in the Initiation and Management of Extracorporeal Membrane Oxygenation". Critical Care Medicine. 48 (6): 838–846. doi: 10.1097/CCM.0000000000004330 . ISSN   0090-3493. PMC   7422732 . PMID   32282350.
22. Broman, Lars Mikael; Taccone, Fabio Silvio; Lorusso, Roberto; Malfertheiner, Maximilian Valentin; Pappalardo, Federico; Di Nardo, Matteo; Belliato, Mirko; Bembea, Melania M.; Barbaro, Ryan P.; Diaz, Rodrigo; Grazioli, Lorenzo (December 2019). "The ELSO Maastricht Treaty for ECLS Nomenclature: abbreviations for cannulation configuration in extracorporeal life support - a position paper of the Extracorporeal Life Support Organization". Critical Care. 23 (1): 36. doi: 10.1186/s13054-019-2334-8 . ISSN   1364-8535. PMC   6367794 . PMID   30736845.
23. Bartlett, Robert H.; Ogino, Mark T.; Brodie, Daniel; McMullan, David M.; Lorusso, Roberto; MacLaren, Graeme; Stead, Christine M.; Rycus, Peter; Fraser, John F.; Belohlavek, Jan; Salazar, Leonardo (May 2020). "Initial ELSO Guidance Document: ECMO for COVID-19 Patients with Severe Cardiopulmonary Failure". ASAIO Journal. 66 (5): 472–474. doi: 10.1097/MAT.0000000000001173 . ISSN   1058-2916. PMC   7273858 . PMID   32243267.
24. Shekar, Kiran; Badulak, Jenelle; Peek, Giles; Boeken, Udo; Dalton, Heidi J; Arora, Lovkesh; Zakhary, Bishoy; Ramanathan, Kollengode; Starr, Joanne; Akkanti, Bindu; Antonini, M. Velia (April 2020). "Extracorporeal Life Support Organization COVID-19 Interim Guidelines". ASAIO Journal. 66 (7): 707–721. doi: 10.1097/MAT.0000000000001193 . ISSN   1058-2916. PMC   7228451 . PMID   32604322.