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Leukemia is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called blasts or leukemia cells. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy.
Jay Robert Inslee is an American politician, lawyer, and economist who has served as the 23rd governor of Washington since 2013. A member of the Democratic Party, he served as a member of the U.S. House of Representatives from 1993 to 1995 and again from 1999 to 2012, and was a candidate for the 2020 Democratic presidential nomination. He is the longest-serving current governor in the United States.
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells. HSCT may be autologous, syngeneic, or allogeneic.
The Fred Hutchinson Cancer Center, formerly known as the Fred Hutchinson Cancer Research Center and also known as Fred Hutch or The Hutch, is a cancer research institute established in 1975 in Seattle, Washington.
Edward Donnall "Don" Thomas was an American physician, professor emeritus at the University of Washington, and director emeritus of the clinical research division at the Fred Hutchinson Cancer Research Center. In 1990 he shared the Nobel Prize in Physiology or Medicine with Joseph E. Murray for the development of cell and organ transplantation. Thomas and his wife and research partner Dottie Thomas developed bone marrow transplantation as a treatment for leukemia.
Moffitt Cancer Center & Research Institute is a nonprofit cancer treatment and research center located in Tampa, Florida. Established in 1981 by the Florida Legislature, the hospital opened in October 1986 on the University of South Florida's campus. Moffitt is one of two National Cancer Institute-designated Comprehensive Cancer Centers based in Florida. In 2021, U.S. News & World Report ranked Moffitt Cancer Center as a top 30 cancer hospital in the United States.
The National Marrow Donor Program (NMDP) is a nonprofit organization founded in 1987 and based in Minneapolis, Minnesota, that operates the Be The Match Registry of volunteer hematopoietic cell donors and umbilical cord blood units in the United States.
Treosulfan, sold under the brand name Trecondi, is a medication given to people before they have a bone marrow transplant from a donor known as allogeneic hematopoietic stem cell transplantation. It is used as a 'conditioning' treatment to clear the bone marrow and make room for the transplanted bone marrow cells, which can then produce healthy blood cells. It is used together with another medicine called fludarabine in adults and children from one month of age with blood cancers as well as in adults with other severe disorders requiring a bone marrow transplant.
Children's Hospital Oakland Research Institute (CHORI) is a biomedical research institute affiliated with California’s pediatric medical center, UCSF Benioff Children's Hospital Oakland.
The Gift of Life Marrow Registry is a non-profit organization founded in 1991 and headquartered in Boca Raton, Florida that operates a public blood stem cell and bone marrow registry while facilitating transplants for children and adults battling life-threatening illnesses, including leukemia, lymphoma, other cancers and genetic diseases.
Allen Charles Edward Eaves is the co-founding Director of the Terry Fox Laboratory for Hematology/Oncology Research, which over a 25-year period (1981–2006) he grew into an internationally recognized centre for the study of leukemia and stem cell research. His own research on chronic myelogenous leukemia (CML) has led the way to a new understanding of the disease. As Head of Hematology at the British Columbia Cancer Agency and the University of British Columbia for 18 years (1985–2003) he engineered the building of one of the first and largest bone marrow transplant programs in Canada. In recognition of his research accomplishments and leadership in moving basic science discoveries in stem cell biology into the clinic, he was elected President of the International Society of Cellular Therapy (1995–1997), Treasurer of the Foundation for the Accreditation of Cellular Therapy (1995–2002) and President of the American Society of Blood and Marrow Transplantation (1999–2000). In 2003 he was awarded the prestigious R. M. Taylor Medal by the Canadian Cancer Society and the National Cancer Institute of Canada.
The 2012 Washington gubernatorial election took place on November 6, 2012. Candidates in the election were chosen in an August 7, 2012 primary election, under the state's nonpartisan blanket primary system, which allows voters to vote for any candidate running in the race, regardless of party affiliation. The two candidates who received the most votes in the primary election qualified for the general election.
The 2016 Washington gubernatorial election was held on November 8, 2016.
Seattle Cancer Care Alliance (SCCA) is a cancer treatment and research center in Seattle, Washington. Established in 1998, this nonprofit provides clinical oncology care for patients treated at its three partner organizations: Fred Hutchinson Cancer Research Center, Seattle Children's and UW Medicine. Together, these four institutions form the Fred Hutch/University of Washington Cancer Consortium.
Dorothy "Dottie" Thomas was an American hematology researcher and administrator known for her work in developing bone marrow transplants. She and her husband, Edward Donnall Thomas, partnered to research leukemia and other blood disorders, and developed the technique for transplanting bone marrow. Her husband was awarded a Nobel Prize in Physiology or Medicine in 1990 due to his discoveries about cell and organ transplantation in the treatment of human diseases that he had completed along with Dorothy. This Nobel Prize was shared with Joseph Edward Murray, an American plastic surgeon.
David G. Maloney is an oncologist and researcher at Fred Hutchinson Cancer Research Center and the University of Washington who specializes in developing targeted immunotherapies for the treatment of blood cancers.
Nancy E. Davidson is the executive director and president of Seattle Cancer Care Alliance, senior vice president, director of clinical oncology at Fred Hutchinson Cancer Research Center and head of the Division of Medical Oncology at the University of Washington School of Medicine. She focuses her research on breast cancer treatments and the genes that are mutated in various forms of breast cancer. She was president of American Association for Cancer Research from 2015 to 2016 and president of American Society of Clinical Oncology from 2007 to 2008.
The 2020 Washington lieutenant gubernatorial election was held on November 3, 2020, to elect the lieutenant governor of Washington concurrently with the 2020 Washington elections. The top-two primary was held on August 4, and Democrats Denny Heck and Marko Liias advanced to the general election, which Heck won.
The 2024 Washington gubernatorial election will be held on November 5, 2024. The top-two primary was held on August 6. Democratic state attorney general Ferguson and Republican former congressman Dave Reichert are seeking their first term in office. The winner will succeed Democratic incumbent Jay Inslee, who is not seeking re-election to a fourth term. Inslee, who previously served in the U.S. House, was first elected governor in 2012 and won re-election in 2016 and 2020 by increasing margins each time.
Karin Dorinda Norlin Rodland is an American cancer cell biologist. She is a professor emeritus at Oregon Health and Science University.
References
- ↑ "Inductees". www.giantsofcancercare.com. Retrieved 31 August 2023.
- ↑ "Fred Appelbaum's "Living Medicine" tells the story of bone marrow transplantation and Don Thomas's discoveries". Cancer History Project. Retrieved 31 August 2023.
- ↑ "Frederick R. Appelbaum, MD". American Association for Cancer Research (AACR). Retrieved 31 August 2023.
- ↑ "RCW 43.348.020: Andy Hill cancer research endowment". app.leg.wa.gov. Retrieved 2024-10-18.
- ↑ "Inslee announces appointments to CARE Fund Board to ensure investment in cancer research | Governor Jay Inslee". governor.wa.gov. Retrieved 2024-10-18.
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