Gypsy (database)

Last updated
GyDB of mobile genetic elements:
Database.png
Content
DescriptionMobile genetic elements
Contact
Primary citation PMID   21036865
Release date2010
Access
Data format Wiki
Website http://gydb.org.
Web service URL mediawiki api
Tools
Web wiki
Miscellaneous
Versionrelease 2.0.

Gypsy (GyDB) is a wiki-style database of mobile genetic elements. [1] [2] [3]

Wiki type of website that visitors can edit

A wiki is a knowledge base website on which users collaboratively modify content and structure directly from the web browser. In a typical wiki, text is written using a simplified markup language and often edited with the help of a rich-text editor.

Mobile genetic elements DNA sequence whose position in the genome is variable

Mobile genetic elements (MGEs) are a type of genetic materials that can move around within a genome, or that can be transferred from one species or replicon to another. MGEs are found in all organisms. In humans, approximately 50% of the genome is thought to be MGEs. MGEs play a distinct role in evolution. Gene duplication events can also happen through the mechanism of MGEs. MGEs can also cause mutations in protein coding regions, which alters the protein functions. In addition, they can also rearrange genes in the host genome. One of the examples of MGEs in evolutionary context is that virulence factors and antibiotic resistance genes of MGEs can be transported to share them with neighboring bacteria. Newly acquired genes through this mechanism can increase fitness by gaining new or additional functions. On the other hand, MGEs can also decrease fitness by introducing disease-causing alleles or mutations.

Contents

See also

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References

  1. ↑ Llorens, Carlos; Futami Ricardo; Covelli Laura; Domínguez-Escribá Laura; Viu Jose M; Tamarit Daniel; Aguilar-Rodríguez Jose; Vicente-Ripolles Miguel; Fuster Gonzalo; Bernet Guillermo P; Maumus Florian; Munoz-Pomer Alfonso; Sempere Jose M; Latorre Amparo; Moya Andres (January 2011). "The Gypsy Database (GyDB) of mobile genetic elements: release 2.0". Nucleic Acids Res. England. 39 (Database issue): D70–4. doi:10.1093/nar/gkq1061. PMC   3013669 . PMID   21036865.
  2. ↑ Lloréns, C; Futami, R; Bezemer, D; Moya, A (January 2008). "The Gypsy Database (GyDB) of mobile genetic elements". Nucleic Acids Research. 36 (Database issue): D38–46. doi:10.1093/nar/gkm697. PMC   2238898 . PMID   17895280.
  3. ↑ Bernet, GP; Muñoz-Pomer, A; Domínguez-Escribá, L; Covelli, L; Bernad, L; Ramasamy, S; Futami, R; Sempere, JM; Moya, A; Llorens, C (July 2011). "GyDB mobilomics: LTR retroelements and integrase-related transposons of the pea aphid Acyrthosiphon pisum genome". Mobile genetic elements. 1 (2): 97–102. doi:10.4161/mge.1.2.17635. PMC   3190316 . PMID   22016855.


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