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Binoculars or field glasses are two refracting telescopes mounted side-by-side and aligned to point in the same direction, allowing the viewer to use both eyes when viewing distant objects. Most binoculars are sized to be held using both hands, although sizes vary widely from opera glasses to large pedestal-mounted military models.
The optical microscope, also referred to as a light microscope, is a type of microscope that commonly uses visible light and a system of lenses to generate magnified images of small objects. Optical microscopes are the oldest design of microscope and were possibly invented in their present compound form in the 17th century. Basic optical microscopes can be very simple, although many complex designs aim to improve resolution and sample contrast.
A spotting scope is a compact lightweight portable telescope optimized for detailed observation of distant objects. They are used as tripod mounted optical enhancement devices for various outdoor activities such as birdwatching, skygazing and other naturalist activities, for hunting and target shooting to verify a marksman's shot placements, for tactical ranging and surveillance, and for any other application that requires higher magnification than ordinary binoculars.
A monocular is a compact refracting telescope used to magnify images of distant objects, typically using an optical prism to ensure an erect image, instead of using relay lenses like most telescopic sights. The volume and weight of a monocular are typically less than half of a pair of binoculars with similar optical properties, making it more portable and also less expensive. This is because binoculars are essentially a pair of monoculars packed together — one for each eye. As a result, monoculars only produce two-dimensional images, while binoculars can use two parallaxed images to produce binocular vision, which allows stereopsis and depth perception.
An optical telescope is a telescope that gathers and focuses light mainly from the visible part of the electromagnetic spectrum, to create a magnified image for direct visual inspection, to make a photograph, or to collect data through electronic image sensors.
In optical engineering, an objective is an optical element that gathers light from an object being observed and focuses the light rays from it to produce a real image of the object. Objectives can be a single lens or mirror, or combinations of several optical elements. They are used in microscopes, binoculars, telescopes, cameras, slide projectors, CD players and many other optical instruments. Objectives are also called object lenses, object glasses, or objective glasses.
An eyepiece, or ocular lens, is a type of lens that is attached to a variety of optical devices such as telescopes and microscopes. It is named because it is usually the lens that is closest to the eye when someone looks through an optical device to observe an object or sample. The objective lens or mirror collects light from an object or sample and brings it to focus creating an image of the object. The eyepiece is placed near the focal point of the objective to magnify this image to the eyes. The amount of magnification depends on the focal length of the eyepiece.
A telescopic sight, commonly called a scope informally, is an optical sighting device based on a refracting telescope. It is equipped with some form of a referencing pattern – known as a reticle – mounted in a focally appropriate position in its optical system to provide an accurate point of aim. Telescopic sights are used with all types of systems that require magnification in addition to reliable visual aiming, as opposed to non-magnifying iron sights, reflector (reflex) sights, holographic sights or laser sights, and are most commonly found on long-barrel firearms, particularly rifles, usually via a scope mount. Similar devices are also found on other platforms such as artillery, tanks and even aircraft. The optical components may be combined with optoelectronics to add night vision or smart device features.
Invasive carcinoma of no special type, invasive breast carcinoma of no special type (IBC-NST), invasive ductal carcinoma (IDC), infiltrating ductal carcinoma (IDC) or invasive ductal carcinoma, not otherwise specified (NOS) is a disease. For international audiences this article will use "invasive carcinoma NST" because it is the preferred term of the World Health Organization (WHO).
Ductal carcinoma in situ (DCIS), also known as intraductal carcinoma, is a pre-cancerous or non-invasive cancerous lesion of the breast. DCIS is classified as Stage 0. It rarely produces symptoms or a breast lump that can be felt, typically being detected through screening mammography. It has been diagnosed in a significant percentage of men.
In digital photography, the image sensor format is the shape and size of the image sensor.
Medullary breast carcinoma is a rare type of breast cancer that is characterized as a relatively circumscribed tumor with pushing, rather than infiltrating, margins. It is histologically characterized as poorly differentiated cells with abundant cytoplasm and pleomorphic high grade vesicular nuclei. It involves lymphocytic infiltration in and around the tumor and can appear to be brown in appearance with necrosis and hemorrhage. Prognosis is measured through staging but can often be treated successfully and has a better prognosis than other infiltrating breast carcinomas.
Metaplastic carcinoma, otherwise known as metaplastic breast cancer (MBC), is a heterogeneous group of cancers that exhibit varied patterns of metaplasia and differentiation along multiple cell lines. This rare and aggressive form of breast cancer is characterized as being composed of a mixed group of neoplasms containing both glandular and non-glandular patterns with epithelial and/or mesenchymal components. It accounts for fewer than 1% of all breast cancer diagnoses. It is most closely associated with invasive ductal carcinoma of no special type (IDC), and shares similar treatment approaches. Relative to IDC, MBC generally has higher histological grade and larger tumor size at time of diagnosis, with a lower incidence of axillary lymph node involvement. MBC tumors are typically estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor-2 (HER-2) negative, meaning hormone therapy is generally not an effective treatment option, which correlates to a relatively poor prognosis. MBC was first recognized as a distinct pathological entity in 2000 by the World Health Organization.
Comedocarcinoma is a kind of breast cancer that demonstrates comedonecrosis, which is the central necrosis of cancer cells within involved ducts. Comedocarcinomas are usually non-infiltrating and intraductal tumors, characterized as a comedo-type, high-grade ductal carcinoma in situ (DCIS). However, there have been accounts of comedocarcinoma which has then diversified into other cell types and developed into infiltrating (invasive) ductal carcinoma. Recurrence and survival rates differ for invasive breast cancer which has originated as comedocarcinoma compared with other types of cancer cells.
The stereo, stereoscopic or dissecting microscope is an optical microscope variant designed for low magnification observation of a sample, typically using light reflected from the surface of an object rather than transmitted through it. The instrument uses two separate optical paths with two objectives and eyepieces to provide slightly different viewing angles to the left and right eyes. This arrangement produces a three-dimensional visualization of the sample being examined. Stereomicroscopy overlaps macrophotography for recording and examining solid samples with complex surface topography, where a three-dimensional view is needed for analyzing the detail.
Breast cancer classification divides breast cancer into categories according to different schemes criteria and serving a different purpose. The major categories are the histopathological type, the grade of the tumor, the stage of the tumor, and the expression of proteins and genes. As knowledge of cancer cell biology develops these classifications are updated.
A macroscope or photomacroscope in its camera-equipped version is a type of optical microscope developed and named by Swiss microscope manufacturers Wild Heerbrugg and later, after that company's merger with Leica in 1987, by Leica Microsystems of Germany, optimised for high quality macro photography and/or viewing using a single objective lens and light path, rather than stereoscopic viewing of specimens, at magnifications up to around x40. The Wild, subsequently Leica "macroscope" line was in production from approximately 1976–2003; it was succeeded by the Leica Z6 and Z16 offerings, which continued an equivalent functionality, but without the "macroscope" designation. The macroscope remains a useful, if somewhat specialised, instrument for examination of relevant specimens in various laboratories today.
Papillary carcinomas of the breast (PCB), also termed malignant papillary carcinomas of the breast, are rare forms of the breast cancers. The World Health Organization (2019) classified papillary neoplasms of the breast into 5 types: intraductal papilloma, papillary ductal carcinoma in situ (PDCIS), encapsulated papillary carcinoma (EPC), solid-papillary carcinoma (SPC), and invasive papillary carcinoma (IPC). The latter four carcinomas are considered here; intraductal papilloma is a benign neoplasm. The World Health Organization regarded solid papillary carcinoma as having two subtypes: in situ and invasive SPC.
A prism sight or prismatic sight, sometimes also called prism scope or prismatic scope, is a type of telescopic sight which uses a reflective prism for its image-erecting system, instead of the series of relay lenses found in traditional telescopic sights. The use of prisms makes it possible to construct a shorter and lighter sight, or with an offset between the eyepiece and objective axes, although restricting the achievable range of magnification.
Pure apocrine carcinoma of the breast (PACB) is a rare carcinoma derived from the epithelial cells in the lactiferous ducts of the mammary gland. The mammary gland is an apocrine gland. Its lactiferous ducts have two layers of epithelial cells, a luminal layer which faces the duct's lumen and a basal layer which lies beneath the luminal layer. There are at least four subtypes of epithelial cells in these ducts: luminal progenitor cells and luminal mature cells which reside in the luminal layer and mammary stem cells and basal cells which reside in the basal layer. Examination of the genes expressed in PACB cancer cells indicate that most of these tumors consist of cells derived from luminal cells but a minority of these tumors consist of cells derived from basal cells.
References
- 1 2 3 4 5 6 Unless otherwise specified in list/table, then reference is: "Infiltrating Ductal Carcinoma of the Breast (Carcinoma of No Special Type)". Stanford University School of Medicine . Archived from the original on 2019-09-11. Retrieved 2019-10-02.
- ↑ Mikael Häggström (2020-01-29). "Neuroendocrine tumors of the midgut". Patholines.org.
- ↑ Normal Reference Range Table Archived 2011-12-25 at the Wayback Machine from the University of Texas Southwestern Medical Center. Used in interactive case study companion to pathologic basis of disease.
- ↑ Robbins Basic Pathology, 9e pg 792
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